Pharmacological Inhibitors of the NLRP3 Inflammasome

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Items 301–400 of 604

1. Allergen-induced NLRP3/caspase1/IL-18 signaling initiate eosinophilic esophagitis and respective inhibitors protect disease pathogenesis
   Chandra Sekhar Yadavalli, Sathisha Upparahalli Venkateshaiah, Sandeep Kumar, Hemanth Kumar Kandikattu, Lokanatha Oruganti, Chandrasekhar Kathera, Anil Mishra · 2023 · Communications Biology
2. Clonal Hematopoiesis Mutations Are Present in Atherosclerotic Lesions in Peripheral Artery Disease
   Petra G Buttner, Julia Böttner, Knut Krohn, Ronny Baber, Uwe Platzbecker, Michael A. Cross, Steffen Desch, Hölger Thiele, Sabine Steiner, Dierk Scheinert et al. · 2023 · International Journal of Molecular Sciences
3. The effect of isovitexin on lipopolysaccharide-induced renal injury and inflammation by induction of protective autophagy.
   Chiao-Yun Tseng, Pei-Rong Yu, Cheng-Chin Hsu, Hui-Hsuan Lin, Jing-Hsien Chen · 2022 · Food and Chemical Toxicology
4. Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors
   David Harrison, Mark G. Bock, John R. Doedens, Christopher A. Gabel, M. Katharine Holloway, Arwel Lewis, Jane Scanlon, Andrew Sharpe, Iain D. Simpson, Pamela J. Smolak et al. · 2022 · ACS Medicinal Chemistry Letters
5. Catching a killer: Mechanisms of programmed cell death and immune activation in Amyotrophic Lateral Sclerosis
   Neel, Dylan V., Basu, Himanish, Gunner, Georgia, Chiu, Isaac M. · 2022 · Immunological Reviews
6. Melatonin Alleviates Neonatal Necrotizing Enterocolitis by Repressing the Activation of the NLRP3 Inflammasome
   Xiaoyu Xiong, Zhongkun Bao, Yanhong Mi, Xinhong Wang, Jiajun Zhu · 2022 · Gastroenterology Research and Practice
7. Therapeutic Interventions Targeting Innate Immune Receptors: A Balancing Act
   Xujun Cao, Anthony F. Cordova, Lingyin Li · 2021 · Chemical Reviews
8. Picroside II alleviates DSS-induced ulcerative colitis by suppressing the production of NLRP3 inflammasomes through NF-κB signaling pathway
   Yao, Huixiang, Yan, Jun, Yin, Li, Chen, Wei · 2022 · Immunopharmacology and Immunotoxicology
9. Cardiovascular Tropism and Sequelae of SARS-CoV-2 Infection
   Oleksandr Dmytrenko, Kory J. Lavine · 2022 · Viruses
10. Effect of parthenolide, an NLRP3 inflammasome inhibitor, on insulin resistance in high-fat diet-obese mice
    Pavan Kumar Chinta, Suhas M. Tambe, Dhananjay N. Umrani, Ajay Kumar Pal, Mukesh Nandave · 2022 · Canadian Journal of Physiology and Pharmacology
11. Ameliorative Effects of Cardamonin on Monosodium Urate-Induced Gouty Arthritis through Inhibiting NLRP3 Inflammasome Mediation
    Chih-Chien Wang, Jeng-Wei Lu, Yi-Jen Peng, Chian H. Lee, Herng-Sheng Lee, You-Hsiang Chu, Chun-Jung Huang, Yi-Jung Ho, Feng-Cheng Liu, Chia-Chun Wu · 2021 · Medicina
12. Small molecule therapeutics for neuroinflammation-mediated neurodegenerative disorders
    Silke Miller, María-Jesús Blanco · 2021 · RSC Medicinal Chemistry
13. Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum
    Kívia Queiroz de Andrade, Cássio Luiz Coutinho Almeida-da-Silva, David M. Ojcius, Robson Coutinho‐Silva · 2021 · Current Research in Microbial Sciences
14. Targeting the NLRP3 inflammasome for calcium oxalate stones: pathophysiology and emerging pharmacological interventions
    Andrew M. Boldt, Francesca Di Sole · 2025 · Frontiers in Physiology
15. MR2938 relieves DSS-induced colitis in mice through inhibiting NF-κB signaling and improving epithelial barrier
    Ling Lv, Mireguli Maimaitiming, Shuli Xia, Ji-Chen Yang, Tian-Tian Zhang, Yuming Wang, Xin Li, Iryna Pinchuk, Ping-Yuan Wang, Chang-Yun Wang et al. · 2025 · Marine Life Science & Technology
16. Mechanism of effect and therapeutic potential of NLRP3 inflammasome in spinal cord injury
    Hou-Yun Gu, Ning Liu · 2024 · Experimental Neurology
17. Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review
    Ziqi Zhang, Yuan Zhang, Meiying Zhang, Chenfeng Yu, Pingping Yang, Minxuan Xu, Jitao Ling, Yuting Wu, Zicheng Zhu, Yixuan Chen et al. · 2023 · Critical Reviews in Food Science and Nutrition
18. Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3
    Liangli Song, Linnan Wang, Xiangchen Li, Longfei Xiao · 2023 · Animals
19. Discovery of NLRP3 inhibitors using machine learning: Identification of a hit compound to treat NLRP3 activation-driven diseases
    Cheng Shi, Xiangyu Zhang, Xiaowei Chi, Yi Ran Zhou, Weiping Lyu, Tongfei Gao, Jiaxu Zhou, Yanming Chen, Chuxiao Yi, Xiaojiao Sun et al. · 2023 · European Journal of Medicinal Chemistry
20. Formaldehyde aggravates allergic contact dermatitis by facilitating NLRP3 inflammasome activation in macrophages
    Huijuan Ma, Qi Shu, Zhiming Li, Xiaodong Song, Huan Xu · 2023 · International Immunopharmacology
21. Relationship of NLRP3 inflammasome with periodontal, endodontic and related systemic diseases
    Revan Birke Koca-Ünsal, A. Sehirli, S. Sayıner, U. Aksoy · 2022 · Molecular Biology Reports
22. XueFu ZhuYu Decoction Alleviates Cardiopulmonary Bypass-Induced NLRP3 Inflammasome-Dependent Pyroptosis by Inhibiting IkB-α/NF-κB Pathway in Acute Lung Injury Rats
    Hui Li, Wenlei Zhang, Qiaoqin Lou, Yuejin Chang, Zhenhao Lin, Lingli Lou · 2022 · Evidence-based Complementary and Alternative Medicine
23. House dust mite‐induced Akt‐ERK1/2‐C/EBP beta pathway triggers CCL20‐mediated inflammation and epithelial–mesenchymal transition for airway remodeling
    Shin-Young Park, Min‐Jeong Kang, Nuri Jin, So-Young Lee, Yun-Young Lee, S. Jo, J. Eom, Heejae Han, Sook In Chung, Kiseok Jang et al. · 2022 · The FASEB Journal
24. The NLRP3 Inflammasome in Stress Response: Another Target for the Promiscuous Cannabidiol
    Alice Hartmann dos Santos, Carla Vila-Verde, Francisco Silveira Guimarães, Sâmia R.L. Joca, Sabrina Francesca de Souza Lisboa · 2022 · Current Neuropharmacology
25. Identification of NLRP3PYD Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity
    Soroush Moasses Ghafary, Paula M. Soriano‐Teruel, Shima Lotfollahzadeh, Mónica Sancho, Eva Serrano‐Candelas, Fatemeh Karami, Stephen Jones Barigye, Iván Fernández-Pérez, Rafael Gozalbes, Maryam Nikkhah et al. · 2022 · International Journal of Molecular Sciences
26. An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7
    Emily A. Caseley, Samuel J Lara Reyna, James A. Poulter, Joanne Topping, Clive R.D. Carter, Fatima Nadat, Gavin P Spickett, Sinisa Savic, Michael McDermott · 2021 · Journal of Clinical Immunology
27. Neonicotinoids and human health: Environmental fate, toxicity mechanisms, and future directions
    Kangming Ji, Yu Rong, Zihang Zhang, Yunjie Chen, Ruixin Hu, Yuchen Chu, Yuyi Tang, Lijun Qian, Chuang Yang · 2025 · Pesticide Biochemistry and Physiology
28. Sprayable inflammasome-inhibiting lipid nanorods in a polymeric scaffold for psoriasis therapy
    Dhanashree H. Surve, Adam Fish, Maharshi Debnath, Aniruddha Pinjari, Adrian A. Lorenzana, Sumi Piya, Shelly R. Peyton, Ashish A. Kulkarni · 2024 · Nature Communications
29. A novel selective NLRP3 inhibitor shows disease-modifying potential in animal models of Parkinson’s disease
    Abhijit Chatterjee, Jogeswar Mohapatra, Manoranjan Sharma, Abhishek Jha, Randeep Patro, Debajeet Das, Hiren Patel, Harilal Patel, Jaimin Chaudhari, Nilesh Borda et al. · 2024 · Brain Research
30. Hydrogen sulfide attenuates uranium‐induced kidney cells pyroptosis via upregulation of PI3K/AKT/mTOR signaling
    Qiaoni Hu, Rui Zhang, Jifang Zheng, Menghui Song, Chaohao Gu, Wanting Li · 2022 · Journal of Biochemical and Molecular Toxicology
31. Purinergic Signaling in the Regulation of Gout Flare and Resolution
    Xiaoling Li, Jie Gao, Jin‐Hui Tao · 2021 · Frontiers in Immunology
32. HMGB1/Foxp1 regulates hypoxia‐induced inflammatory response in macrophages
    Jing Hu, Xiaojun Liu, Yu Tang · 2021 · Cell Biology International
33. Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes
    Alessandra Petrelli, Mark A. Atkinson, Massimo Pietropaolo, Nick Giannoukakis · 2021 · Diabetes
34. A narrative review of positive regulation of NLRP3 inflammasome in rheumatoid arthritis.
    Yue-Peng Zhuang, Huan Wang, Jiang Su, Jing Zhang, Qian Wang, Ya-Nan Chen, Huaping Che · 2021 · Annals of Palliative Medicine
35. Interleukin-1β and cancer immune response
    Cédric Rébé, François Ghiringhelli · 2025 · Seminars in Immunology
36. NLRP3 inflammasome: From drug target to drug discovery
    Ling Yin, Hongliang Zhang, Yuhua Shang, Songquan Wu, Tengchuan Jin · 2025 · Drug Discovery Today
37. Neuroprotective potential of tranilast in streptozotocin-induced sporadic Alzheimer's disease model targeting TXNIP-NLRP3 inflammasome pathway
    Dibya Sundar Padhy, Kushal Vesmaker, Sugato Banerjee · 2025 · International Immunopharmacology
38. NLRP3 Inflammasome: A New Target for the Treatment of CVD and Depression Comorbidity
    Chen Chen, Siqi Zhang, Ming Sheng, Wei Shao · 2025 · Mediators of Inflammation
39. Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
    Jue Wang, Man Wu, V. Magupalli, P. Dahlberg, Hao Wu, Grant J. Jensen · 2024 · bioRxiv
40. Methamphetamine Enhancement of HIV-1 gp120-Mediated NLRP3 Inflammasome Activation and Resultant Proinflammatory Responses in Rat Microglial Cultures
    Debashis Dutta, Jianuo Liu, Enquan Xu, Huangui Xiong · 2024 · International Journal of Molecular Sciences
41. Implications of NLRP3 Suppression Using Glibenclamide and miR-223 against Colorectal Cancer
    Shaimaa Hamza, Ekaterina Evgenevna Garanina, Layaly Shkair, Ali Al-Saadi, Svetlana Francevna Khaiboullina, Gülçin Tezcan · 2024 · Pharmaceuticals
42. Possible role of the NLRP3 inflammasome and the gut–brain axis in multiple sclerosis‐related depression
    Karina Maciak, Angela Dziedzic, Joanna Saluk · 2022 · The FASEB Journal
43. P2X7R-NEK7-NLRP3 Inflammasome Activation: A Novel Therapeutic Pathway of Qishen Granule in the Treatment of Acute Myocardial Ischemia
    Yanqin Li, Xiaoqian Sun, Xiangning Liu, Junjun Li, Xuan Li, Gang Wang, Yizhou Liu, Xiangyu Lu, Lingwen Cui, Mingyan Shao et al. · 2022 · Journal of Inflammation Research
44. Clostridium difficile Induced Inflammasome Activation and Coagulation Derangements
    Marta Mattana, Riccardo Tomasello, C. Cammarata, P. Di Carlo, T. Fasciana, Giulio Giordano, A. Lucchesi, S. Siragusa, M. Napolitano · 2022 · Microorganisms
45. Shared Inflammatory Pathology of Stroke and COVID-19
    Kathryn E. Sánchez, Gary A. Rosenberg · 2022 · International Journal of Molecular Sciences
46. The NLRP3 inflammasome in age-related eye disease: Evidence-based connexin hemichannel therapeutics
    Odunayo Omolola Mugisho, Colin Richard Green · 2021 · Experimental Eye Research
47. GPR40 agonist inhibits NLRP3 inflammasome activation via modulation of nuclear factor-κB and sarco/endoplasmic reticulum Ca2+-ATPase
    Jeongwoo Park, Moo‐Yeol Lee, Yoon‐Seok Seo, Byeongseok Kang, Sung‐Chul Lim, Keon Wook Kang · 2021 · Life Sciences
48. Volcanic Ash as a Precursor for SARS-CoV-2 Infection Among Susceptible Populations in Ecuador: A Satellite Imaging and Excess Mortality-Based Analysis
    Theofilos Toulkeridis, Rachid Seqqat, Marbel Torres Arias, Rodolfo Salazar Martínez, Esteban Ortiz‐Prado, Scarlet Chunga, Karla Sofía Vizuete, Marco Heredia-R, Alexis Debut · 2021 · Disaster Medicine and Public Health Preparedness
49. Protective effects of oridonin against cerebral ischemia/reperfusion injury by inhibiting the NLRP3 inflammasome activation.
    Yu-Jie Jia, Yu Tong, Lianqiu Min, Yanrong Li, Yan Cheng · 2021 · Tissue & Cell
50. Looking into the future of sarcoidosis: what is next for treatment?
    Jelle Miedema, Francesco Bonella, Johan Grünewald, Paolo Spagnolo · 2020 · Current Opinion in Pulmonary Medicine
51. Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates
    Zi-Kun Tu, Haiyan Guo, Yajing Gao, Wenfeng Xiao, Xue-Ru Xie, Hongmiao Yu, Qiu-Yan Liang, Yu-Feng Zhou · 2025 · Frontiers in Immunology
52. NLRP3 Inflammasome in Vascular Dementia: Regulatory Mechanisms, Functions, and Therapeutic Implications: A Comprehensive Review
    Yujia Lu, Lin Cheng, Yinyi Xiong, Chunyan Huang, Ziying Liu, Chunxiao Shen, Huaying Wang, Yuemin Qiu, Seung‐Bum Yang, Maoxiong Wu et al. · 2025 · CNS Neuroscience & Therapeutics
53. Euterpe oleracea Mart. Bioactive Molecules: Promising Agents to Modulate the NLRP3 Inflammasome
    Carolina Bordin Davidson, Dana El Soufi El Sabbagh, Amanda Kolinski Machado, Lauren Pappis, Michele Rorato Sagrillo, Sabrina Somacal, Tatiana Emanuelli, Júlia Vaz Schultz, João Augusto Pereira da Rocha, André Flores dos Santos et al. · 2024 · Biology
54. Microglial modulation as a therapeutic strategy in Alzheimer's disease: Focus on microglial preconditioning approaches
    Younes Yassaghi, Yasaman Nazerian, Mobina Ghasemi, Amirhossein Nazerian, Fatemeh Sayehmiri, George L. Perry, Hamid Gholami Pourbadie · 2024 · Journal of Cellular and Molecular Medicine
55. Role of inflammasomes in endothelial dysfunction
    Jimin Wu, Melody Shyy, John Y.‐J. Shyy, Han Xiao · 2024 · British Journal of Pharmacology
56. Tranilast alleviates visceral hypersensitivity and colonic hyperpermeability by suppressing NLRP3 inflammasome activation in irritable bowel syndrome rat models
    Tsukasa Nozu, Hideyuki Arie, Saori Miyagishi, Masatomo Ishioh, Kaoru Takakusaki, Toshikatsu Okumura · 2024 · International Immunopharmacology
57. Molecular regulation of NLRP3 inflammasome activation during parasitic infection
    Rasha Alonaizan · 2024 · Bioscience Reports
58. Integrated Proteomics Characterization of NLRP3 Inflammasome Inhibitor MCC950 in Monocytic Cell Line Confirms Direct MCC950 Engagement with Endogenous NLRP3
    Heng Zhao, Praveen Kumar, Tiago J. P. Sobreira, Mackenzie L. Smith, Steven J. Novick, Anders Johansson, Anna Łuchniak, Andrew X. Zhang, Kevin J. Woollard, Niklas Larsson et al. · 2024 · ACS Chemical Biology
59. Targeted-Neuroinflammation Mitigation Using Inflammasome-Inhibiting Nanoligomers is Therapeutic in Experimental Autoimmune Encephalomyelitis (EAE) Mouse Model
    Sadhana Sharma, Sydney J. Risen, Vincenzo S. Gilberto, Sean W. Boland, Anushree Chatterjee, Julie A. Moreno, Prashant Nagpal · 2024 · bioRxiv
60. Regulation of cellular senescence by innate immunity
    Jinxiu Hou, Yi Zheng, Chengjiang Gao · 2023 · Biophysics Reports
61. Betanin combined with virgin coconut oil inhibits neuroinflammation in aluminum chloride-induced toxicity in rats by regulating NLRP3 inflammasome
    Baban S. Thawkar, Ginpreet Kaur · 2023 · Journal of Traditional and Complementary Medicine
62. Convergence of Fructose-Induced NLRP3 Activation with Oxidative Stress and ER Stress Leading to Hepatic Steatosis
    Sushmita Singh, Aditya Sharma, Shadab Ahmad, Bhavimani Guru, Farah Gulzar, Pawan Kumar, Ishbal Ahmad, A. Tamrakar · 2022 · Inflammation
63. Immunomodulatory Effects of Aronia Juice Polyphenols—Results of a Randomized Placebo-Controlled Human Intervention Study and Cell Culture Experiments
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64. Macrophage-targeted shikonin-loaded nanogels for modulation of inflammasome activation
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65. Melatonin: A potential therapeutic agent against COVID-19
    Sangiliyandi Gurunathan, M. Kang, Youngsok Choi, R. Reiter, Jin-Hoi Kim · 2021 · Melatonin Research
66. Mechanism of Astragalus Polysaccharide in Alleviating Bovine Mammary Fibrosis Through ROS/NLRP3 Inhibition and EMT Regulation
    Jiang Zhang, Kejiang Liu, Tingji Yang, Hongwei Duan, Longfei Xiao, Quanwei Zhang, Yong Zhang, Weitao Dong, Xingxu Zhao · 2025 · Antioxidants
67. NLRP3 inflammasomes pathway: a key target for Metformin
    Yasamin Hosseini, Amirhossein Niknejad, Ayeh Sabbagh Kashani, Mahsa Gholami, Mahtab Roustaei, Mohammad Kazem Mohammadi, Saeideh Momtaz, Stephen Lawrence Atkin, Tannaz Jamialahmadi, Amir Hossein Abdolghaffari et al. · 2025 · Inflammopharmacology
68. Effects of the S1P/S1PR1 Signaling Pathway on High Glucose-Induced NRK-52E Epithelial-Mesenchymal Transition Via Regulation of ROS/NLRP3
    Jihua Tian, Jingshu Chen, Qiuyue Sun, Taiping Huang, Huanyu Xu, Jing Wang, Zhijie Ma · 2024 · Inflammation
69. Repurposing FDA-approved drugs as NLRP3 inhibitors against inflammatory diseases: machine learning and molecular simulation approaches
    Vipul Agarwal, Rajesh Haldhar, Abdurahman Hajinur Hirad, Bilal Ahmed, Sang Beom Han, Anugya Gupta, Vinit Raj, Sang Kil Lee · 2024 · Journal of Biomolecular Structure and Dynamics
70. Panaxydol extracted from Panax ginseng inhibits NLRP3 inflammasome activation to ameliorate NASH-induced liver injury
    Mi‐Yeon Kim, Birang Jeong, Geun‐Shik Lee, Hongjun Jeon, Yoon Mee Yang, Yang HJ, Yong‐Hyun Han · 2024 · International Immunopharmacology
71. Target Cell Activation of a Structurally Novel NOD-Like Receptor Pyrin Domain-Containing Protein 3 Inhibitor NT-0796 Enhances Potency
    P. Smolak, Mytrang Nguyen, Christine Diamond, Heather Wescott, J. Doedens, Kenneth Schooley, J. Snouwaert, Mark G. Bock, David Harrison, Alan P. Watt et al. · 2024 · Journal of Pharmacology and Experimental Therapeutics
72. Non-coding RNAs modulate pyroptosis in myocardial ischemia-reperfusion injury: A comprehensive review.
    Yi Sun, Shu-Juan Chu, Rong Wang, Rui Xia, Meng Sun, Zhi-Xiong Gao, Zhengyuan Xia, Yan Zhang, Si-Wei Dong, Ting-Ting Wang · 2023 · International Journal of Biological Macromolecules
73. NLRP3 Inflammasome: An Emerging Therapeutic Target for Alzheimer’s Disease
    Shuqi Tao, Wenyuan Fan, Jinmeng Liu, Tong Wang, Haoning Zheng, Gaoxiu Qi, Yanchun Chen, Haoyun Zhang, Zhangyu Guo, Fenghua Zhou · 2023 · Journal of Alzheimer s Disease
74. Mefloquine targets NLRP3 to reduce lipopolysaccharide‐induced systemic inflammation and neural injury
    Siyuan Jiang, Tian Tian, Wenjie Li, Ting Liu, Cong Wang, Gang Hu, Ren‐Hong Du, Yang Liu, Ming Lu · 2023 · EMBO Reports
75. A novel sorbicillinoid compound as a potent anti‐inflammation agent through inducing NLRP3 protein degradation
    Fangfang Wang, Meng Zhang, Meng Yuan, Zixuan Xia, Fengge Yang, Sihao Zhang, Tengyu Lin, Lianxiang Luo, Jinshan Tang, Youwei Zhang · 2023 · British Journal of Pharmacology
76. Diabetes mellitus: Lessons from COVID-19 for monkeypox infection
    Juan Alberto Ruiz‐Pacheco, L. Díaz, Ramón Arreola-Torres, Salvador Fonseca-Coronado, B Gómez-Navarro · 2023 · Primary care diabetes
77. Annexin A1 inhibition facilitates NLRP3 inflammasome activation in arsenic-induced insulin resistance in rat liver
    Chenbing Wu, Tianming Qiu, Weizhuo Yuan, Yan Shi, Xiaofeng Yao, Liping Jiang, Jingyuan Zhang, Guang Yang, Xiaofang Liu, Jie Bai et al. · 2022 · Environmental Toxicology and Pharmacology
78. Strategies of Targeting Inflammasome in the Treatment of Systemic Lupus Erythematosus
    Ya-Ling Liu, Xi Tao, Jin-Hui Tao · 2022 · Frontiers in Immunology
79. Nanophysical Mapping of Inflammasome Activation by Nanoparticles via Specific Cell Surface Recognition Events
    Cristina Lo Giudice, Jinsung Yang, Mégane A. Poncin, Laurent Adumeau, Martin Delguste, Melanie Koehler, Koen Evers, Andra C. Dumitru, Kenneth A. Dawson, David Alsteens · 2021 · ACS Nano
80. Effects of Osthole on Inflammatory Gene Expression and Cytokine Secretion in Histamine-Induced Inflammation in the Caco-2 Cell Line
    Natalia Karolina Kordulewska, Justyna Topa, Dominika Rozmus, Beata Jarmołowska · 2021 · International Journal of Molecular Sciences
81. Emerging role of the itaconate-mediated rescue of cellular metabolic stress
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82. Exploring the Role of NLRP3 in Neurodegeneration: Cutting‐Edge Therapeutic Strategies and Inhibitors
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83. Targeting inflammasomes as a therapeutic potential for HIV/AIDS
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84. Anthocyanin-Rich Fraction from Kum Akha Black Rice Attenuates NLRP3 Inflammasome-Driven Lung Inflammation In Vitro and In Vivo
    Sonthaya Umsumarng, Warathit Semmarath, Punnida Arjsri, Kamonwan Srisawad, Intranee Intanil, S. Jamjod, C. Prom-u-thai, Pornngarm Dejkriengkraikul · 2025 · Nutrients
85. Anti-inflammatory Therapies for Ischemic Heart Disease
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86. Breaking the barriers: Overcoming cancer resistance by targeting the NLRP3 inflammasome
    Nazanin Pazhouhesh Far, Mahsa Hajiheidari Varnousafaderani, Ferdos Faghihkhorasani, Sareh Etemad, Al‐Hasnawi Rasool Riyadh Abdulwahid, Negar Bakhtiarinia, Afsaneh Mousaei, Elahe Dortaj, Soroush Karimi, Nasim Ebrahimi et al. · 2024 · British Journal of Pharmacology
87. The role and mechanism of pyroptosis and potential therapeutic targets in non-alcoholic fatty liver disease (NAFLD)
    Shujing Li, An-Bu Liu, Yuanyuan Yu, Jin-Hai Ma · 2024 · Frontiers in Cell and Developmental Biology
88. In Vivo Effects of Bay 11-7082 on Fibroid Growth and Gene Expression: A Preclinical Study
    Tsai‐Der Chuang, Nhu Ton, Shawn Rysling, Omid Khorram · 2024 · Cells
89. Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects
    Huiting Hu, Yuqian Cai, Yuanfang Shi, Shengyu Zhang, Xiaoxuan Yu, Tonghui Ma, Shanting Liao · 2024 · iScience
90. Structural modification based on the diclofenac scaffold: Achieving reduced colitis side effects through COX-2/NLRP3 selective inhibition
    Zhiran Ju, Junde Xu, Keshuang Tang, Fen‐Er Chen · 2024 · European Journal of Medicinal Chemistry
91. miR-155-5p/FOXO3a promotes pulmonary fibrosis in rats by mediating NLRP3 inflammasome activation
    Ling Wu, Pu Li, Zhifang Zhuang · 2022 · Immunopharmacology and Immunotoxicology
92. NLRP3 Inflammasome as a Therapeutic Target for Atherosclerosis: A Focus on Potassium Outflow
    Yi-Jing Jin, Zhuo‐Yu An, Zhixuan Sun, Xin-Chen Liu · 2022 · Reviews in Cardiovascular Medicine
93. Chalcone Derivatives From Abelmoschus manihot Seeds Restrain NLRP3 Inflammasome Assembly by Inhibiting ASC Oligomerization
    Jinsong Su, Fujing Yang, Xuemei Kang, Jia Liu, Yiwen Tao, Qing-Chun Diao, Xian-Li Meng, De-Ming Liu, Y. Zhang · 2022 · Frontiers in Pharmacology
94. The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches
    Siva Prasad Panda, Yogita Dhurandhar, Mehak Agrawal · 2022 · Mitochondrion
95. Emergency Hematopoiesis in the Pathobiology of COVID-19: The Dark Side of an Early Innate Protective Mechanism
    Juan Carlos Balandrán, Gabriela Zamora-Herrera, Rubí Romo‐Rodríguez, Rosana Pelayo · 2022 · Journal of Interferon & Cytokine Research
96. Fructose-mediated NLRP3 activation induces inflammation and lipogenesis in adipose tissue
    Sushmita Singh, Aditya Sharma, Bhavimani Guru, Shadab Ahmad, Farah Gulzar, Pawan Kumar, Ishbal Ahmad, Akhilesh Kumar Tamrakar · 2022 · The Journal of Nutritional Biochemistry
97. Exploring the Mechanism of Ling-Gui-Zhu-Gan Decoction in Ventricular Remodeling after Acute Myocardial Infarction Based on UPLC and In Vivo Experiments
    Peng Zhou, Meng Zhang, Xiao-ni Zhao, Tong-Juan Tang, Xiang-Peng Wang, Lu-Lu Huang, Qingzan Kong, Liang Wang, Jin-Ling Huang · 2022 · Evidence-Based Complementary and Alternative Medicine
98. Interleukin-1 signaling in solid organ malignancies
    Austin R. Dosch, Samara P. Singh, Nagaraj S. Nagathihalli, Jashodeep Datta, Nipun B. Merchant · 2021 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
99. NLRP3 inflammasome: A joint, potential therapeutic target in management of COVID-19 and fertility problems
    M. Bazrafkan, Elham Hosseini, M. Nazari, C. Amorim, M. Sadeghi · 2021 · Journal of Reproductive Immunology
100. The NLRP3 Inflammasome in the Pathogenesis and Treatment of Alzheimer’s Disease
     Mahdieh Golzari-Sorkheh, Carla E. Brown, Donald Fredric Weaver, Mark A. Reed · 2021 · Journal of Alzheimer s Disease