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Cited by 98Gut microbiota and healthAlzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

The Gastrointestinal Tract Microbiome and Potential Link to Alzheimer’s Disease

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Hill, James M., Bhattacharjee, Surjyadipta, Pogue, Aileen I., Lukiw, Walter J.·2014·Frontiers in Neurology
DOI 10.3389/fneur.2014.00043PMC PMC3983497
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  • Gut microbiome composition and metabolome are altered in many brain disorders.

    “Interestingly, several studies have found that the gut microbiome composition and, consequently, metabolome are altered in many brain disorders (138–142).”

    From The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication (2020) · cites this paper as [138]

    The paper’s main text (page unavailable) discusses altered gut microbiota in relation to neurological disease and describes microbiome-generated molecules that can reach the CNS. It does not establish that both gut microbiome composition and the metabolome are altered across many brain disorders; it presents several of these links as emerging or hypothetical. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

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References 55 · Cited by 98

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Authors
Hill, J. M., Bhattacharjee, S., Pogue, A. I., & Lukiw, W. J.
Affiliations
Louisiana State University Health Sciences Center New Orleans (US)
Corresponding author
Lukiw, Walter J.
ORCID
Venue
Frontiers in Neurology
Publisher
Frontiers Media SA
Published
2014-04-04
Volume
5
Pages
43-43
ISSN
1664-2295 (ISSN-L)
DOI
10.3389/fneur.2014.00043
PMC
PMC3983497
OpenAlex
W2043981492
Cited by
98
References
55
Citations by year
2026: 2 · 2025: 7 · 2024: 5 · 2023: 4 · 2022: 14 · 2021: 9 · 2020: 11 · 2019: 9 · 2018: 13 · 2017: 5 · 2016: 11 · 2015: 6 · 2014: 2
FWCI
0.75
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Neurology (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • Research to Prevent Blindness (NIA AG038834)
  • Louisiana Biomedical Research Network
  • National Institute on Aging (AG038834, NIA AG038834, R01AG038834)
  • National Eye Institute (R01EY006311, EY-006311)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
gut microbiota, gastrointestinal tract, Alzheimer's disease, gut-brain axis, neurodegeneration

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