Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders

Cites (330)

Items 201–330 of 330

1. WldS requires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration
   Michelle A. Avery, Amy E. Sheehan, Kimberly S. Kerr, Jing Wang, Marc R. Freeman · 2009 · The Journal of Cell Biology
2. Activation of the unfolded protein response enhances motor recovery after spinal cord injury
   C. Hetz, V. Valenzuela, Eileen Collyer, Donna Armentano, G. Parsons, Felipe A. Court · 2012 · Cell Death and Disease
3. Activation of the Innate Signaling Molecule MAVS by Bunyavirus Infection Upregulates the Adaptor Protein SARM1, Leading to Neuronal Death
   Piyali Mukherjee, Tyson A. Woods, Roger A. Moore, Karin E. Peterson · 2013 · Immunity
4. A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity
   Yanshan Fang, Lorena Soares, Xiuyin Teng, Melissa Geary, Nancy M. Bonini · 2012 · Current Biology
5. Caloric Restriction in Older Adults—Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function
   Kristin Prehn, Reiner Jumpertz von Schwartzenberg, Knut Mai, Ulrike Zeitz, A. Veronica Witte, Dierk J. Hampel, Anna-Maria Szela, Sonja Fabian, Ulrike Grittner, Joachim Spranger et al. · 2016 · Cerebral Cortex
6. Aberrant epigenome in iPSC‐derived dopaminergic neurons from Parkinson's disease patients
   Rubén Fernández‐Santiago, Iria Carballo‐Carbajal, Giancarlo Castellano, Roger Torrent, Yvonne Richaud, Adriana Sánchez‐Danés, Roser Vilarrasa‐Blasi, Álex Sánchez‐Pla, José Luis Mosquera, Jordi Soriano et al. · 2015 · EMBO Molecular Medicine
7. Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy
   Hsiao-Chun Cheng, Sang Ryong Kim, Tinmarla Frances Oo, Tatyana Kareva, Olga Yarygina, Margarita Rzhetskaya, Chuansong Wang, Matthew J. During, Zsolt Tallóczy, Keiji Tanaka et al. · 2011 · Journal of Neuroscience
8. Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration into the segmental motor circuitry
   Leyan Xu, David K. Ryugo, Tan Pongstaporn, Karl K. Johe, Vassilis E. Koliatsos · 2009 · The Journal of Comparative Neurology
9. The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death
   Naohiro Egawa, Keisuke Yamamoto, Haruhisa Inoue, Rie Hikawa, Katsunori Nishi, Kazutoshi Mori, Ryōsuke Takahashi · 2010 · Journal of Biological Chemistry
10. Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage
    Sarah J. Hill, Daniel A. Mordes, Lisa Cameron, Donna S Neuberg, Serena Landini, Kevin C. Eggan, David M. Livingston · 2016 · Proceedings of the National Academy of Sciences
11. Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease
    Wei Zhao, Merina Varghese, Prashant Vempati, Anastasiya Dzhun, Alice Cheng, Jun Wang, Dale J. Lange, Amanda E. Bilski, Irene Faravelli, Giulio Maria Pasinetti · 2012 · PLoS ONE
12. A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis
    Isabella Fogh, Antonia Ratti, Cinzia Gellera, K. Lin, Cinzia Tiloca, Valentina Moskvina, Lucia Corrado, Gianni Sorarú, Cristina Cereda, Stefania Paola Corti et al. · 2013 · Human Molecular Genetics
13. SARM1-specific motifs in the TIR domain enable NAD + loss and regulate injury-induced SARM1 activation
    Daniel W. Summers, Daniel A. Gibson, Aaron DiAntonio, Jeffrey Milbrandt · 2016 · Proceedings of the National Academy of Sciences
14. Aging and caloric restriction impact adipose tissue, adiponectin, and circulating lipids
    Karl N. Miller, Maggie S. Burhans, Josef P. Clark, Porsha R. Howell, Michael A. Polewski, Tyler M. DeMuth, Kevin W. Eliceiri, Mary J. Lindstrom, James Mukasa Ntambi, Rozalyn M. Anderson · 2017 · Aging Cell
15. Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice
    Han, Byung Hee, Zhou, Meng-liang, Johnson, Andrew W., Singh, Itender, Liao, Fan, Vellimana, Ananth K., Nelson, James W., Milner, Eric, Cirrito, John R., Basak, Jacob et al. · 2015 · Proceedings of the National Academy of Sciences
16. Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
    Chiung-Ya Chen, Chia-Wen Lin, Chiung-Ying Chang, Si‐Tse Jiang, Yi‐Ping Hsueh · 2011 · The Journal of Cell Biology
17. Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy
    David W. Hampton, Daniel J. Webber, Bilada Bilican, Michel Goedert, Maria Grazia Spillantini, Siddharthan Chandran · 2010 · Journal of Neuroscience
18. The mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice
    Lee J. Martin, Samantha Semenkow, Allison Rose Hanaford, Margaret Wong · 2013 · Neurobiology of Aging
19. Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease
    Sara Sepe, Chiara Milanese, Sylvia Gabriels, Kasper Derks, César Payán‐Gómez, Wilfred F. J. van IJcken, Yvonne Rijksen, Alex L. Nigg, Sandra Moreno, Silvia Cerri et al. · 2016 · Cell Reports
20. A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons
    Debolina Ghosh, Kelsey R. LeVault, Aaron Barnett, Gregory J. Brewer · 2012 · Journal of Neuroscience
21. Mammalian Sir2-related protein (SIRT) 2–mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: A crucial role of tubulin deacetylation
    Kazuhiko Suzuki, Takayoshi Koike · 2007 · Neuroscience
22. The Pathophysiology of Concussion
    Meeryo C. Choe · 2016 · Current Pain and Headache Reports
23. Circadian Dbp Transcription Relies on Highly Dynamic BMAL1-CLOCK Interaction with E Boxes and Requires the Proteasome
    Markus Stratmann, David M. Suter, Nacho Molina, Félix Naef, Ueli Schibler · 2012 · Molecular Cell
24. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models
    Mathew M. Blurton-Jones, Brian J. Spencer, Sara Michael, Nicholas A. Castello, Andranik A. Agazaryan, Joy L. Davis, Franz-Josef Müller, Jeanne F. Loring, Eliezer Masliah, Frank M. LaFerla · 2014 · Stem Cell Research & Therapy
25. Altered systemic iron metabolism in Parkinson's disease
    Giancarlo Logroscino, Karen S. Marder, Joseph H. Graziano, G A Freyer, Vesna N. Slavkovich, Nancy J. LoIacono, L. J. Cote, Richard P Mayeux · 1997 · Neurology
26. Calorie restriction ameliorates neurodegenerative phenotypes in forebrain-specific presenilin-1 and presenilin-2 double knockout mice
    Pu Wu, Qian Shen, Suzhen Dong, Zhiliang Xu, Joe Z. Tsien, Yinghe Hu · 2007 · Neurobiology of Aging
27. The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse
    Lindsey R. Fischer, Deborah G. Culver, Albert A. Davis, Philip Tennant, Min-Sheng Wang, Michael P. Coleman, Seneshaw Asress, Róbert Adalbert, Guillermo M. Alexander, Jonathan D. Glass · 2005 · Neurobiology of Disease
28. Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease
    Baohua Cheng, Xinxin Yang, Liangxiang An, Bo Gao, Xia Liu, Shuwei Liu · 2009 · Brain Research
29. Guidelines for the preclinical in vivo evaluation of pharmacological active drugs for ALS/MND: Report on the 142nd ENMC international workshop
    Albert Christian Ludolph, Caterina Bendotti, Eran Blaugrund, Bastian Hengerer, Jean‐Philippe Loeffler, Joanne E. Martin, Vincent Meininger, Thomas Meyer, Saliha M. Moussaoui, Wim Robberecht et al. · 2007 · Amyotrophic Lateral Sclerosis
30. The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model
    Moustapha Cissé, Eric Duplan, Thomas Lorivel, Julie Dunys, Charlotte Bauer, Xavier Meckler, Yannis Gerakis, Inger Lauritzen, Frédéric Checler · 2016 · Molecular Psychiatry
31. A genome‐wide profiling of brain DNA hydroxymethylation in Alzheimer's disease
    Jinying Zhao, Yun Zhu, Jingyun Yang, Li Lin, Hao Wu, Philip L. De Jager, Peng Jin, David Alan Bennett · 2017 · Alzheimer s & Dementia
32. Longitudinal changes of tau PET imaging in relation to hypometabolism in prodromal and Alzheimer’s disease dementia
    Konstantinos Chiotis, Laure Saint‐Aubert, Elena Rodriguez‐Vieitez, Antoine Leuzy, Ove Almkvist, Irina Savitcheva, My Jonasson, Mark Lubberink, A. Wall, Gunnar Antoni et al. · 2017 · Molecular Psychiatry
33. Axonal transport defects are a common phenotype in Drosophila models of ALS
    Katie R. Baldwin, Vinay K. Godena, Victoria L. Hewitt, Alexander J. Whitworth · 2016 · Human Molecular Genetics
34. AAV transduction of dopamine neurons with constitutively active rheb protects from neurodegeneration and mediates axon regrowth
    Kim, Sang Ryong, Kareva, Tatyana, Yarygina, Olga, Kholodilov, Nikolai, Burke, Robert E · 2012 · Molecular Therapy
35. Oxidative damage to proteins and lipids of CNS myelin produced by in vitro generated reactive oxygen species
    Ernesto Roque Bongarzone, Juana Maria Pasquini, Eduardo F. Soto · 1995 · Journal of Neuroscience Research
36. Alteration of soluble adhesion molecules during aging and their modulation by calorie restriction
    Zou, Yani, Jung, Kyung Jin, Kim, Jung Won, Yu, Byung Pal, Chung, Hae Young · 2004 · The FASEB Journal
37. Epigenetic oxidative redox shift (EORS) theory of aging unifies the free radical and insulin signaling theories
    Gregory J. Brewer · 2009 · Experimental Gerontology
38. Analytical tools and current challenges in the modern era of neuroepigenomics
    Maze, Ian, Shen, Li, Zhang, Bin, Garcia, Benjamin A, Shao, Ningyi, Mitchell, Amanda, Sun, HaoSheng, Akbarian, Schahram, Allis, C David, Nestler, Eric J · 2014 · Nature Neuroscience
39. Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
    Maritza Oñate, Alejandra Catenaccio, Gabriela Martínez, Donna Armentano, Geoffrey Parsons, Bredford Kerr, Claudio A. Hetz, Felipe A. Court · 2016 · Scientific Reports
40. ALS Along the Axons – Expression of Coding and Noncoding RNA Differs in Axons of ALS models
    Nimrod Rotem, Iddo Magen, Ariel Ionescu, Noga Gershoni‐Emek, Topaz Altman, Christopher J. Costa, Tal Gradus, Metsada Pasmanik‐Chor, Dianna E. Willis, Iddo Z. Ben‐Dov et al. · 2017 · Scientific Reports
41. Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning
    Seanna M. Martin, Georgeann S. O’Brien, Carlos Portera‐Cailliau, Alvaro Sagasti · 2010 · Development
42. Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer’s Disease
    Michael Stefan Unger, Julia Marschallinger, Julia Kaindl, Corinna Höfling, Steffen Roßner, Michael Thomas Heneka, Annemie Van der Linden, Ludwig Aigner · 2016 · Molecular Neurobiology
43. Old and new challenges in Parkinson's disease therapeutics
    Ana O. Pires, Fábio Gabriel Teixeira, Bárbara Mendes-Pinheiro, Sofia Cravino Serra, Nuno Sousa, António José Salgado · 2017 · Progress in Neurobiology
44. NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo
    M. Di Stefano, Andrea Loreto, Giuseppe Orsomando, Valerio Mori, Federica Zamporlini, Richard P. Hulse, Jamie Webster, Lucy Frances Donaldson, Martin Gering, Nadia Raffaelli et al. · 2017 · Current Biology
45. Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis
    Hitoshi Kikuchi, Akiko Furuta, Kenichi Nishioka, Satoshi O. Suzuki, Yusaku Nakabeppu, Toru Iwaki · 2002 · Acta Neuropathologica
46. Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain
    Adam R. Smith, Rebecca G. Smith, Daniel Condliffe, Eilis J. Hannon, Leonard C. Schalkwyk, Jonathan S. Mill, Katie Lunnon · 2016 · Neurobiology of Aging
47. Hyperglycemia Induces Oxidative Stress and Impairs Axonal Transport Rates in Mice
    Ruchi G. Sharma, Eric Dale Buras, Tomoya Terashima, Faridis Serrano, Cynthia A. Massaad, Lingyun Hu, Brittany R. Bitner, Taeko Inoue, Lawrence Chan, Robia G. Pautler · 2010 · PLoS ONE
48. The role of TNF-α during Wallerian degeneration
    Matthias Liefner, H. Siebert, T.I. Sachse, Uwe Michel, George A. Kollias, Wolfgang Brück · 2000 · Journal of Neuroimmunology
49. Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis
    Mohamad J. Alshikho, Nicole R. Zürcher, Marco L. Loggia, Paul Cernasov, Daniel B. Chonde, David Izquierdo‐Garcia, Julia E. Yasek, Oluwaseun Akeju, Ciprian Catana, Bruce Robert Rosen et al. · 2016 · Neurology
50. Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response
    Vyacheslav M. Labunskyy, Maxim V. Gerashchenko, Joe Ryan Delaney, Alaattin Kaya, Brian Keith Kennedy, Matt R. Kaeberlein, Vadim N. Gladyshev · 2014 · PLoS Genetics
51. Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules
    Liu Yang, Shaohua Li, Linqing Miao, Haoliang Huang, Feisi Liang, Xiuyin Teng, Lin Xu, Wang Qizhao, Weidong Xiao, William H. Ridder et al. · 2016 · Journal of Neuroscience
52. Age-related loss of CpG methylation in the tumour necrosis factor promoter
    Isobel Gowers, Kevin Walters, Endre Kiss‐Toth, Robert Charles Read, Gordon W. Duff, Anthony Gerard Wilson · 2011 · Cytokine
53. Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients
    Yoshiro Saito, Takao Hamakubo, Yasukazu Yoshida, Yoko Ogawa, Yasuo Hara, Harutoshi Fujimura, Yasuharu Imai, Hiroko Iwanari, Yasuhiro Mochizuki, Mototada Shichiri et al. · 2009 · Neuroscience Letters
54. Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis
    Afsaneh Shirani, Darin T. Okuda, Olaf Stüve · 2016 · Neurotherapeutics
55. Dendrobium nobile Lindl alkaloid, a novel autophagy inducer, protects against axonal degeneration induced by Aβ25‐35 in hippocampus neurons in vitro
    Lisheng Li, Yanliu Lu, Jing Nie, Yun‐Yan Xu, Wei Zhang, Wen‐Jin Yang, Qihai Gong, Yuan‐Fu Lu, Lu Yang, Jingshan Shi · 2017 · CNS Neuroscience & Therapeutics
56. Initial-Rate Kinetics of Human NMN-Adenylyltransferases: Substrate and Metal Ion Specificity, Inhibition by Products and Multisubstrate Analogues, and Isozyme Contributions to NAD+ Biosynthesis
    Leonardo Sorci, Flavio Cimadamore, Stefania Scotti, Riccardo Petrelli, Loredana Cappellacci, Palmarisa Franchetti, Giuseppe Orsomando, Giulio Magni · 2007 · Biochemistry
57. Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis
    Simone Patergnani, Valentina Fossati, Massimo Bonora, Carlotta Giorgi, Saverio Marchi, Sonia Missiroli, Tom Rusielewicz, Mariusz Roman Wieckowski, Paolo Pinton · 2016 · International review of cytology
58. Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice
    So-Young Han, Jong-Ryoul Choi, Ki Soon Shin, Shin Jung Kang · 2012 · Brain Research
59. Intermittent Fasting Improves Functional Recovery after Rat Thoracic Contusion Spinal Cord Injury
    Miae Jeong, Ward T. Plunet, Femke Streijger, Jae H.T. Lee, Jason R. Plemel, Sophia Park, Clarrie K. Lam, Jie Liu, Wolfram Tetzlaff · 2011 · Journal of Neurotrauma
60. AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington’s disease
    Amparo Zuleta, René L. Vidal, Donna Armentano, Geoffrey Parsons, Claudio A. Hetz · 2012 · Biochemical and Biophysical Research Communications
61. Wildtype motoneurons, ALS‐Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling
    Blandine Madji Hounoum, Sylvie Mavel, Emmanuelle Coque, Franck Patin, Patrick Vourc’h, Sylviane Marouillat, Lydie Nadal‐Desbarats, Patrick Emond, Philippe Corcia, Christian Robert Andres et al. · 2017 · Glia
62. Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients
    Véronique Belzil, Peter O. Bauer, Tania F. Gendron, Melissa Erin Murray, Dennis W. Dickson, Leonard Petrucelli · 2014 · Brain Research
63. α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responses
    Naoto Sugeno, Sandra Jäckel, Aaron Voigt, Zinah Wassouf, Julia Maria Schulze-Hentrich, Philipp J. Kahle · 2016 · Scientific Reports
64. Biological theories of aging
    Martin Stephen Lipsky, Mitch King · 2015 · Disease-a-Month
65. Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster
    Arshad Ayyaz, Heinrich Jasper · 2013 · Frontiers in Cellular and Infection Microbiology
66. Developing dopaminergic cell therapy for Parkinson's disease—give up or move forward?
    Olle Lindvall · 2013 · Movement Disorders
67. Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot–Marie–Tooth disease
    Irina Madorsky, Katherine Opalach, Amanda J. Waber, Jonathan D. Verrier, Chelsea Solmo, Thomas C. Foster, William A. Dunn, Lucia M. Notterpek · 2009 · Neurobiology of Disease
68. The Neuroprotective Factor Wlds Does Not Attenuate Mutant SOD1-Mediated Motor Neuron Disease
    Christine Vande Velde, Michael L. Garcia, Xinghua Yin, Bruce D. Trapp, Don W. Cleveland · 2004 · NeuroMolecular Medicine
69. α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1
    Paula Desplats, Brian J. Spencer, Leslie A. Crews, Pruthul Pathel, Dinorah Morvinski-Friedmann, Kori Ann Kosberg, Scott Roberts, Christina Patrick, Beate Winner, Jürgen Winkler et al. · 2012 · Journal of Biological Chemistry
70. Sciatic Nerve Regeneration by Microporous Nerve Conduits Seeded With Glial Cell Line‐Derived Neurotrophic Factor or Brain‐Derived Neurotrophic Factor Gene Transfected Neural Stem Cells
    Keng‐Yen Fu, Lien‐Guo Dai, Ing‐Ming Chiu, Jeng‐Rung Chen, Shan‐hui Hsu · 2011 · Artificial Organs
71. Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease
    Ting Wang, Jesse Hay · 2015 · Frontiers in Neuroscience
72. The Role of Macromolecular Damage in Aging and Age-related Disease
    Arlan G Richardson, Eric E. Schadt · 2014 · The Journals of Gerontology Series A
73. Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence
    Porkodi Panneerselvam, Laishram Pradeepkumar Singh, Bow Ho, Jianzhu Chen, Jeak Ling Ding · 2011 · Biochemical Journal
74. Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster
    Åsa Fredriksson, Elin Johansson Krogh, Malin Hernebring, Ellinor Pettersson, Ala Javadi, Alvar Almstedt, Thomas Nyström · 2012 · Aging Cell
75. Motor axon excitability during Wallerian degeneration
    Mihai Moldovan, Susana Alvarez, Christian Krarup · 2008 · Brain
76. Oxidative stress induces axonal beading in cultured human brain tissue
    Ben Roediger, Patricia J. Armati · 2003 · Neurobiology of Disease
77. Diapause Formation and Downregulation of Insulin-Like Signaling via DAF-16/FOXO Delays Axonal Degeneration and Neuronal Loss
    Andrea Calixto, Juan Sebastián Jara, Felipe A. Court · 2012 · PLoS Genetics
78. Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS
    Amanjot Kaur Riar, Suzanne R. Burstein, Gloria M. Palomo, Andrea J. Arreguin, Giovanni Manfredi, Doris Germain · 2017 · Human Molecular Genetics
79. Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver
    Kalavathi Dasuri, Le Zhang, Philip J. Ebenezer, Ying Liu, Sun Ok Fernandez‐Kim, Jeffrey N. Keller · 2009 · Mechanisms of Ageing and Development
80. Progressive supranuclear palsy (PSP): Richardson syndrome and other PSP variants
    Grisel J. Lopez, Kemal Bayülkem, Mark Hallett · 2016 · Acta Neurologica Scandinavica
81. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration
    Shuji Wakatsuki, Shinji Tokunaga, Megumi Shibata, Toshiyuki Araki · 2017 · The Journal of Cell Biology
82. Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?
    Körner, Sonja, Böselt, Sebastian, Thau, Nadine, Rath, Klaus Jan, Dengler, Reinhard, Petri, Susanne · 2013 · Neurodegenerative Diseases
83. The Unfolded Protein Response and Cholesterol Biosynthesis Link Luman/CREB3 to Regenerative Axon Growth in Sensory Neurons
    Zhengxin Ying, Ruiling Zhai, Nikki A. McLean, Jayne M. Johnston, Vikram Misra, Valerie M. K. Verge · 2015 · Journal of Neuroscience
84. Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains
    Chia-Wen Lin, Hsin‐Yu Liu, Chiung-Ya Chen, Yi‐Ping Hsueh · 2013 · Innate Immunity
85. Is Axonal Degeneration a Key Early Event in Parkinson’s Disease?
    Zuzanna Kurowska, Jeffrey H. Kordower, A. Jon Stoessl, Robert E. Burke, Patrik Brundin, Zhenyu Yue, Scott T. Brady, Jeffrey Milbrandt, Bruce D. Trapp, Todd Sherer et al. · 2016 · Journal of Parkinson s Disease
86. Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration In Vivo
    Thomas M. Wishart, Timothy M. Rooney, Douglas J. Lamont, Ann K. Wright, A. Jennifer Morton, M. T. Jackson, Marc R. Freeman, Thomas Henry Gillingwater · 2012 · PLoS Genetics
87. Autophagy, and BiP level decrease are early key events in retrograde degeneration of motoneurons
    Penas, C, Font-Nieves, M, Forés, J, Petegnief, V, Planas, A, Navarro, X, Casas, C · 2011 · Cell Death & Differentiation
88. Epigenomics and the Regulation of Aging
    Jerome Douglas Boyd-Kirkup, Christopher D. Green, Gang Wu, Dan Wang, Jing‐Dong J. Han · 2013 · Epigenomics
89. Neuronal endoplasmic reticulum stress in axon injury and neurodegeneration
    Shaohua Li, Yang Liu, Michael E. Selzer, Yang Hu · 2013 · Annals of Neurology
90. Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge
    Jose Antonio Gomez-Sanchez, Clara Gomis-Coloma, Cruz Morenilla‐Palao, Gloria Peiró, Eduard Serra, Manuel Serrano, Hugo Cabedo · 2013 · Brain
91. The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury
    Elisabetta Mantuano, Kenneth W. Henry, Tomonori Yamauchi, Nobuhiko Hiramatsu, Kazuyo Yamauchi, Sumihisa Orita, Kazuhisa Takahashi, Jonathan H. Lin, Steven L. Gonias, W. Marie Campana · 2011 · Journal of Neuroscience
92. Axonopathy in Huntington's disease
    Li, Jia-Yi, Conforti, Laura · 2013 · Experimental Neurology
93. Autophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy
    Nathalie Launay, Carmen Aguado, Stéphane Fourcade, Montserrat Ruíz, Laia Grau, Jordi Riera, Cristina Guilera, Marisa Girós, Isidró Ferrer, Erwin Knecht et al. · 2014 · Acta Neuropathologica
94. Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF)
    Yoni Genzer, Maayan Dadon‐Freiberg, Chen Burg, Nava Chapnik, Oren Froy · 2016 · Molecular and Cellular Endocrinology
95. Network Analyses Reveal Novel Aspects of ALS Pathogenesis
    Mario Sanhueza, Andrea Chai, Colin Smith, Brett A. McCray, T. Ian Simpson, J. Paul Taylor, Giuseppa Pennetta · 2015 · PLoS Genetics
96. Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease
    Rodolfo G. Gatto, Yaping Chu, Allen Q. Ye, Steven D. Price, Ehsan Tavassoli, Andrea Buenaventura, Scott T. Brady, Richard L. Magin, Jeffrey H. Kordower, Gerardo A. Morfini · 2015 · Human Molecular Genetics
97. Neural Stem Cells Enhance Nerve Regeneration after Sciatic Nerve Injury in Rats
    Lin Xu, Shuai Zhou, Guo-Ying Feng, Luping Zhang, Dongmei Zhao, Yi Sun, Qian Liu, Fei Huang · 2012 · Molecular Neurobiology
98. Postnatal development- and age-related changes in DNA-methylation patterns in the human genome
    Paraskevi Salpea, Valya R. RUSSANOVA, Tazuko H. Hirai, Thomae G. Sourlingas, Kalliope E. Sekeri‐Pataryas, Roberto J. Romero, Jonathan Epstein, Bruce H. Howard · 2012 · Nucleic Acids Research
99. CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer’s disease
    Maite Mendióroz, Naiara Celarain, Miren Altuna, Javier Sánchez‐Ruiz de Gordoa, María Victoria Zelaya, Miren Roldán, Idoya Rubio, R Larumbe, María Elena Erro, Iván Méndez-López et al. · 2016 · Alzheimer s Research & Therapy
100. Epigenetic changes in T‐cell and monocyte signatures and production of neurotoxic cytokines in ALS patients
     Larry Lam, Lydia Chin, Ramesh Chandra Halder, Bien Sagong, Sam Famenini, James William Sayre, Dennis J. Montoya, Liudmilla Rubbi, Matteo A. Pellegrini, Milan Fiala · 2016 · The FASEB Journal
101. Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy
     John C. Means, Anandakrishnan Venkatesan, Bryan C. Gerdes, Jin-Yuan Fan, Edward S. Bjes, Jeffrey L. Price · 2015 · PLoS Genetics
102. Improved proteostasis in the secretory pathway rescues Alzheimer’s disease in the mouse
     Yajing Peng, Mi Jin Kim, Rikki Hullinger, Kenneth J. O’Riordan, Corinna Bürger, Mariana Pehar, Luigi Puglielli · 2016 · Brain
103. Regulation of global gene expression and cell proliferation by APP
     Yili Wu, Si Zhang, Qin Xu, Haiyan Zou, Weihui Zhou, Fang Cai, Tingyu Li, Weihong Song · 2016 · Scientific Reports
104. Age-related axonal swellings precede other neuropathological hallmarks in a knock-in mouse model of Huntington's disease
     Martina Marangoni, Róbert Adalbert, Lucie Janečková, Jane Patrick, Jaskaren S. Kohli, Michael P. Coleman, Laura Conforti · 2014 · Neurobiology of Aging
105. The origin and development of plaques and phosphorylated tau are associated with axonopathy in Alzheimer’s disease
     Ai-Wu Xiao, Jing He, Qian Wang, Yi Luo, Yan Sun, Yanping Zhou, Guan Yang, Paul John Lucassen, Jiapei Dai · 2011 · Neuroscience Bulletin
106. Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease
     Anuska V. Andjelkovic, Joel S. Pachter · 1998 · Journal of Neuroscience Research
107. Gene therapy to target ER stress in brain diseases
     Vicente Valenzuela, Gabriela Martínez, Claudia A. Duran-Aniotz, Claudio A. Hetz · 2016 · Brain Research
108. Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis
     Melania Filareti, Silvia Luotti, Laura Pasetto, Mauro Pignataro, Katia Paolella, Paolo Messina, Elisabetta Pupillo, Massimiliano Filosto, Christian Lunetta, Jessica Mandrioli et al. · 2017 · Frontiers in Molecular Neuroscience
109. The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation
     Catherine Ash, Benjamin J. Merry · 2010 · Mechanisms of Ageing and Development
110. Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration
     Li Chen, Derek M. R. Nye, Michelle C. Stone, Alexis T. Weiner, Kyle W. Gheres, Xin Xiong, Catherine A. Collins, Melissa M. Rolls · 2016 · PLoS Genetics
111. Genome-wide screening identifies new genes required for stress-induced phase 2 detoxification gene expression in animals
     Helen M Crook-McMahon, Monika Oláhová, Emma L Button, Johnathan J Winter, Elizabeth A. Veal · 2014 · BMC Biology
112. Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis
     Kimmy Su, Costanza Savino, Gail Marracci, Priya Chaudhary, Xiaolin Yu, Brooke Morris, Danielle Galipeau, Marco Giorgio, Michael A. Forte, DENNIS N. BOURDETTE · 2012 · European Journal of Neuroscience
113. Resveratrol delays Wallerian degeneration in a NAD+ and DBC1 dependent manner
     Aldo J. Calliari, Natalia Bobba, Carlos Escande, Eduardo N. Chini · 2013 · Experimental Neurology
114. C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells
     Rustam Esanov, Kinsley C. Belle, Marka van Blitterswijk, Véronique Belzil, Rosa Rademakers, Dennis W. Dickson, Leonard Petrucelli, Khrista Boylan, Derek Michael Dykxhoorn, Joanne Wuu et al. · 2015 · Experimental Neurology
115. A novel SOD1 gene mutation in familial ALS with low penetrance in females
     T. Murakami, Hitoshi Warita, Takeshi Hayashi, Kota Sato, Yasuhiro Manabe, S. Mizuno, K Yamane, Koji Abe · 2001 · Journal of the Neurological Sciences
116. Body fat distribution in Parkinson's disease: An MRI-based body fat quantification study
     Denise Bernhardt, Hans‐Peter Müller, Albert Christian Ludolph, Luc Dupuis, Jan Kassubek · 2016 · Parkinsonism & Related Disorders
117. Could sirtuin activities modify ALS onset and progression?
     Tang, Bor Luen · 2017 · Cellular and Molecular Neurobiology
118. Sirtuins as therapeutic targets of ALS
     Giulio Maria Pasinetti, Amanda E. Bilski, Wei Zhao · 2013 · Cell Research
119. The pathology of primary progressive multiple sclerosis
     C. Lucchinetti, W. Brück · 2004 · Multiple Sclerosis
120. Potassium channel abnormalities are consistent with early axon degeneration of motor axons in the G127X SOD1 mouse model of amyotrophic lateral sclerosis
     Rikke Maglemose, Anne Hedegaard, Janna Lehnhoff, K. P. Dimintiyanova, Mihai Moldovan, L. Grøndahl, Claire Francesca Meehan · 2017 · Experimental Neurology
121. RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency
     Amy C. Ladd, David G. Brohawn, Ravindar R. Thomas, Paula M. Keeney, Stuart S. Berr, Shaharyar M. Khan, Francisco R. Portell, Meiram Shakenov, Patrick F Antkowiak, Bijoy Kundu et al. · 2017 · Brain Research
122. Oxidative damage to myelin proteins accompanies peripheral nerve motor dysfunction in aging C57BL/6 male mice
     Ryan Hamilton, Michael Walsh, Rashmi Prabha Singh, Karl A. Rodriguez, Xiaoli Gao, Md Mizanur Rahman, Asish Ray Chaudhuri, Arunabh Bhattacharya · 2016 · Journal of the Neurological Sciences
123. Nutrigenomics
     Michelle Grayson · 2010 · Nature
124. Altered DNA methylation and RNA splicing could be key mechanisms in Huntington disease
     Heather B. Wood · 2013 · Nature Reviews Neurology
125. Longevity focuses on NAD+
     Heinrich Jasper · 2013 · Nature Chemical Biology
126. Reduced levels of alpha-1-antitrypsin in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a novel approach for a potential treatment
     Uri Wormser, Jessica Mandrioli, Marco Vinceti, Nicola Fini, Amnon C. Sintov, Berta Brodsky, Elena Proskura, Yoram Finkelstein · 2016 · Journal of Neuroinflammation
127. The axon degeneration gene SARM1 is evolutionarily distinct from other TIR domain-containing proteins
     Harsha Malapati, Spencer M. Millen, William Buchser · 2017 · Molecular Genetics and Genomics
128. The Interaction of Alpha-synuclein with Membranes and its Implication in Parkinson's Disease: A Literature Review
     Azucena González-Horta · 2015 · Natural Product Communications
129. SARM1: A candidate gene in the onset of hereditary infectious/inflammatory diseases✯
     M MINK, Katalin Csiszar · 2005 · Clinical Immunology
130. Drosophila Neuronal Injury Follows a Temporal Sequence of Cellular Events Leading to Degeneration at the Neuromuscular Junction
     Barron L. Lincoln, Sahar H. Alabsi, Nicholas Frendo, Robert Freund, Lani C. Keller · 2015 · Journal of Experimental Neuroscience