Echocardiographic Evaluation of Ventricular Function—For the Neonatologist and Pediatric Intensivist
Open accessAbstract
In the neonatal and pediatric intensive care setting, bedside cardiac ultrasound is often used to assess ventricular dimensions and function. Depending upon the underlying disease process, it is necessary to be able to evaluate the systolic and diastolic function of left and or right ventricles. The systolic function of left ventricle is mostly assessed qualitatively on visual inspection "eye-balling" and quantitatively by measuring circumferential fraction shortening or calculating the ejection fraction by Simpson's planimetry. The assessment of left ventricular diastolic function relies essentially on the mitral valve and pulmonary venous Doppler tracings or tissue Doppler evaluation. The right ventricular particular shape and anatomical position does not permit to use the same parameters for measuring systolic function as is used for the LV. Tricuspid annular plane systolic excursion (TAPSE) and S' velocity on tissue Doppler imaging are more often used for quantitative assessment of right ventricle systolic function. Several parameters proposed to assess right ventricle systolic function such as fractional area change, 3D echocardiography, speckle tracking, and strain rate are being researched and normal values for children are being established. Diastolic function of right ventricle is evaluated by tricuspid valve and hepatic venous Doppler tracings or on tissue Doppler evaluation. The normal values for children are pretty similar to adults while normal values for the neonates, especially preterm infants, may differ significantly from adult population. The normal values for most of the parameters used to assess cardiac function in term neonates and children have now been established.
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In neonates without shunting, echocardiographic measurement of cardiac output is generally reliable, with values ranging between 150 and 300 mL/kg/min.
“In neonates without shunting, echocardiographic measurement of cardiac output is generally reliable, with values ranging between 150 and 300 mL/kg/min [53,54].”
From Trends and Challenges in Noninvasive Hemodynamic Monitoring of Neonates Following Cardiac Surgery: A Narrative Review (2025) · cites this paper as [53]
The “Evaluation of CO and Cardiac Index” section says echocardiographic cardiac-output measurement is fairly reliable even in neonates and is reliable in children without shunts. It gives normal values of 150–400 mL/kg/day for infants and children, not the claimed 150–300 mL/kg/min; no page number is available in our copy. (LLM, conf=0.90)
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- Authors
- Tissot, C., Singh, Y., & Sekarski, N.
- Affiliations
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Centre Hospitalier Universitaire Vaudois (CH)
- Corresponding author
- Sekarski, Nicole
- Venue
- Frontiers in Pediatrics
- Publisher
- Frontiers Media SA
- Published
- 2018-04-04
- Volume
- 6
- Pages
- 79-79
- ISSN
- 2296-2360 (ISSN-L)
- PMC
- PMC5893826
- OpenAlex
- W2795722279
- Cited by
- 181
- References
- 52
- Citations by year
- 2026: 19 · 2025: 22 · 2024: 23 · 2023: 35 · 2022: 36 · 2021: 19 · 2020: 21 · 2019: 6
- FWCI
- 2.14
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Pediatrics (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- SERVAL (Université de Lausanne) (publishedVersion, cc-by)
- IRIS (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Centre Hospitalier Universitaire Vaudois
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Ultrasound in Clinical Applications
- Keywords
- ventricular function, neonatal echocardiography, pediatric intensive care, left ventricular systolic function, left ventricular diastolic function, right ventricular systolic function, right ventricular diastolic function, ejection fraction, tissue Doppler imaging, tricuspid annular plane systolic excursion, fractional area change, reference values, preterm infants, neonates
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