The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Bacteriocins as Potential Anticancer Agents
Open accessAbstract
Cancer remains one of the leading causes of deaths worldwide, despite advances in its treatment and detection. The conventional chemotherapeutic agents used for the treatment of cancer have non-specific toxicity toward normal body cells that cause various side effects. Secondly, cancer cells are known to develop chemotherapy resistance in due course of treatment. Thus, the demand for novel anti-cancer agents is increasing day by day. Some of the experimental studies have reported the therapeutic potential of bacteriocins against various types of cancer cell lines. Bacteriocins are ribosomally-synthesized cationic peptides secreted by almost all groups of bacteria. Some bacteriocins have shown selective cytotoxicity toward cancer cells as compared to normal cells. This makes them promising candidates for further investigation and clinical trials. In this review article, we present the overview of the various cancer cell-specific cytotoxic bacteriocins, their mode of action and efficacies.
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Cites
Bacteriocins: Developing innate immunity for food
Cotter, P. D., Hill, C., & Ross, R. P. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1273 · Cited by 2,380
Kamarajan, P., Hayami, T., Matte, B., Liu, Y., Danciu, T., Ramamoorthy, A., Worden, F., Kapila, S., & Kapila, Y. (2015) · PLOS ONE · doi:10.1371/journal.pone.0131008 · Cited by 214
Cited by
Functions and emerging applications of bacteriocins
Chikindas, M. L., Weeks, R., Drider, D., Chistyakov, V. A., & Dicks, L. M. (2018) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2017.07.011 · Cited by 574
Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations
Soltani, S., Hammami, R., Cotter, P. D., Rebuffat, S., Said, L. B., Gaudreau, H., Bédard, F., Biron, E., Drider, D., & Fliss, I. (2021) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaa039 · Cited by 544
Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions
Coelho, M. C., Malcata, F. X., & Silva, C. C. G. (2022) · Foods · doi:10.3390/foods11152276 · Cited by 276
“Other studies have also suggested the use of bacteriocins as potential anticancer agents [244,248].”
Bacteriocin production: A relatively unharnessed probiotic trait?
Hegarty, J. W., Guinane, C. M., Ross, R. P., Hill, C., & Cotter, P. D. (2016) · F1000Research · doi:10.12688/f1000research.9615.1 · Cited by 141
Bacteriocins: Perspective for the development of novel anticancer drugs
Baindara, P., Korpole, S., & Grover, V. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9420-8 · Cited by 139
Metadata
- Authors
- Kaur, S., & Kaur, S.
- Venue
- Frontiers in Pharmacology
- Publisher
- Frontiers Media SA
- Published
- 2015-11-10
- Volume
- 6
- Pages
- 272-272
- ISSN
- 1663-9812 (ISSN-L)
- OpenAlex
- W2176673138
- Cited by
- 269
- References
- 2
- FWCI
- 5.14
- Type
- journal article
- Language
- en
- Open access
- gold
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