The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Mitochondria, endothelial cell function, and vascular diseases
Open accessAbstract
Mitochondria are perhaps the most sophisticated and dynamic responsive sensing systems in eukaryotic cells. The role of mitochondria goes beyond their capacity to create molecular fuel and includes the generation of reactive oxygen species, the regulation of calcium, and the activation of cell death. In endothelial cells, mitochondria have a profound impact on cellular function under both healthy and diseased conditions. In this review, we summarize the basic functions of mitochondria in endothelial cells and discuss the roles of mitochondria in endothelial dysfunction and vascular diseases, including atherosclerosis, diabetic vascular dysfunction, pulmonary artery hypertension, and hypertension. Finally, the potential therapeutic strategies to improve mitochondrial function in endothelial cells and vascular diseases are also discussed, with a focus on mitochondrial-targeted antioxidants and calorie restriction.
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Citations
Cites
Biochemistry and molecular cell biology of diabetic complications
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A role for mitochondria in nlrp3 inflammasome activation
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Libby, P., Ridker, P. M., & Hansson, G. K. (2011) · Nature · doi:10.1038/nature10146 · Cited by 4,010
Mitochondrial membrane permeabilization in cell death
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Extending Healthy Life Span—From Yeast to Humans
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Mitochondria and cell death: outer membrane permeabilization and beyond
Tait, S. W. G., & Green, D. R. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2952 · Cited by 2,593
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Cited by
Incalza, M. A., D'Oria, R., Natalicchio, A., Perrini, S., Laviola, L., & Giorgino, F. (2018) · Vascular Pharmacology · doi:10.1016/j.vph.2017.05.005 · Cited by 1,356
Oxidative Stress in Preeclampsia and Placental Diseases
Aouache, R., Biquard, L., Vaiman, D., & Miralles, F. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051496 · Cited by 631
Eelen, G., de Zeeuw, P., Treps, L., Harjes, U., Wong, B. W., & Carmeliet, P. (2018) · Physiological Reviews · doi:10.1152/physrev.00001.2017 · Cited by 572
Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes
Seferović, P. M., & Paulus, W. J. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv134 · Cited by 552
Blood-Brain Barrier Disruption by Lipopolysaccharide and Sepsis-Associated Encephalopathy
Peng, X., Luo, Z., He, S., Zhang, L., & Li, Y. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.768108 · Cited by 267
Metadata
- Authors
- Tang, X., Luo, Y.-X., Chen, H.-Z., & Liu, D.-P.
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2014-05-06
- Volume
- 5
- Pages
- 175-175
- ISSN
- 1664-042X (ISSN-L)
- OpenAlex
- W2131204966
- Cited by
- 345
- References
- 30
- FWCI
- 10.10
- Type
- journal article
- Language
- en
- Open access
- gold
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- Tang, X., Luo, Y.-X., Chen, H.-Z., & Liu, D.-P. (2014). Mitochondria, endothelial cell function, and vascular diseases. Frontiers in Physiology. https://doi.org/10.3389/fphys.2014.00175
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
