Date Palm Tree (Phoenix dactylifera L.): Natural Products and Therapeutic Options
Open accessAbstract
Many plants, including some of the commonly consumed herbs and spices in our daily food, can be safely and effectively used to prevent and/or treat some health concerns. For example, caffeine the active ingredient found in coffee beans (Coffea), shows biological activity in the treatment of the central nervous system (CNS) disorders, indole-3-carbinol and 3,3'-diindolylmethane are both broccoli (Brassica oleracea) derived phytochemicals with potential anti-cancer activity, and resveratrol, isolated from grape (Vitis vinifera), is reported to extend lifespan and provide cardio-neuro-protective, anti-diabetic, and anti-cancer effects. Date palm fruits possess high nutritional and therapeutic value with significant antioxidant, antibacterial, antifungal and anti-proliferative properties. This review focuses on the date fruits extracts and their benefits in individual health promoting conditions and highlights their application as useful to the nutraceutical and pharmaceutical industries in the development of natural compound-based products.
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Flavonoids possess antioxidant properties that can help prevent cardiovascular diseases and chronic illnesses.
“Flavonoids, a significant class of polyphenolic secondary metabolites derived from plants, possess antioxidant properties that can help prevent cardiovascular diseases and chronic illnesses [88, 91].”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [88]
The Flavonoids section (page unavailable) describes flavonoids as plant-derived polyphenolic metabolites with antioxidant benefits. Therapeutic options (page unavailable) links antioxidants to heart disease and other chronic diseases and reports that a date-fruit flavonol fraction enhanced cholesterol removal from macrophages. It does not establish that flavonoids themselves prevent cardiovascular or chronic diseases, even though the claim is hedged as a possibility. (LLM, conf=0.82)
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Ajibola, O. O. (2025) · Discover Food · doi:10.1007/s44187-025-00746-3 · Cited by 3 · see citing works
“Phenolic acids are important aromatic secondary plant metabolites characterized by hydroxyl functional groups attached to aromatic benzene rings and one or more carboxylic acid groups [88].”
- Authors
- Al-Alawi, R. A., Al-Mashiqri, J. H., Al-Nadabi, J. S. M., Al-Shihi, B. I., & Baqi, Y.
- Affiliations
- Sultan Qaboos University (OM)
- Corresponding author
- Baqi, Younis
- ORCID
- Baqi, Younis
- Venue
- Frontiers in Plant Science
- Publisher
- Frontiers Media SA
- Published
- 2017-05-23
- Volume
- 8
- Pages
- 845-845
- ISSN
- 1664-462X (ISSN-L)
- PMC
- PMC5440559
- OpenAlex
- W2619734047
- Cited by
- 336
- References
- 2
- Citations by year
- 2026: 17 · 2025: 41 · 2024: 56 · 2023: 50 · 2022: 56 · 2021: 44 · 2020: 29 · 2019: 28 · 2018: 13 · 2017: 2
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Plant Science (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Arab-German Young Academy of Sciences and Humanities (AGYA_TP_16_27)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Date Palm Research Studies
- Health Sciences › Nursing › Nutrition and Dietetics › Pomegranate: compositions and health benefits
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- date palm, date fruit extract, phytochemicals, antioxidant activity, antibacterial activity, antifungal activity, antiproliferative activity, nutraceuticals, pharmaceutical applications, health-promoting properties
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