Genetic and environmental influences on gambling: a meta-analysis of twin studies
Open accessAbstract
Disentangling the genetic and environmental influences of gambling is important for explaining the roots of individual differences in gambling behavior and providing guidance for precaution and intervention, but we are unaware of any comprehensive and systematic quantitative meta-analysis. We systematically identified 18 twin studies on gambling in the meta-analysis. The correlation coefficients within monozygotic (MZ) and dizygotic (DZ) twins, along with the corresponding sample size, were used to calculate the proportion of the total variance accounted for by additive genes (A), dominant genes (D), the shared environment (C), and the non-shared environment plus measurement error (E). We further assessed the moderating effects of gambling assessment (symptom oriented assessment vs. behavior oriented assessment), age, and sex. The whole sample analyses showed moderate additive genetic (a² = 0.50) and non-shared environmental influences (e² = 0.50) on gambling. The magnitude of the genetic influence (a²) was higher for disordered gambling assessed with symptom oriented assessment (53%) than for general gambling assessed with behavior oriented assessment (41%). Additionally, the magnitude of the genetic influence (a²) was higher for adults (53%) than adolescents (42%). Genetic influence (a2) was greater for male (47%) gambling than female (28%) gambling. Shared environment had noticeable effects on female gambling (c²=14%) but zero effect on male gambling. In conclusion, gambling behavior was moderately heritable and moderately influenced by non-shared environmental factors. Gambling assessment, age, and sex significantly moderated the magnitude of genetic and environmental influences on gambling. Note that the number of studies might serve as a limitation.
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There is a significant genetic contribution to gambling disorder.
“Data suggest a signi fi cant genetic contribution to gambling disorder (Lobo, 2016; Potenza, 2017, 2018; Xuan et al., 2017)”
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“to gambling disorder (Lobo, 2016; Potenza, 2017, 2018; Xuan et al., 2017) and unspecified internet-use disorder (Hahn, Reuter, Spinath, & Montag, 2017).”
- Authors
- Xuan, Y.-H., Li, S., Tao, R., Chen, J., Rao, L.-L., Wang, X. T., & Zheng, R.
- Affiliations
- Chinese Academy of Sciences (CN)
- University of South Dakota (US)
- Corresponding author
- Zheng, Rui
- Venue
- Frontiers in Psychology
- Publisher
- Frontiers Media SA
- Published
- 2017-12-05
- Volume
- 8
- Pages
- 2121-2121
- ISSN
- 1664-1078 (ISSN-L)
- PMC
- PMC5723410
- OpenAlex
- W2773750813
- Cited by
- 26
- References
- 55
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 5 · 2019: 6
- FWCI
- 0.46
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Psychology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Institutional Repository of Institute of Psychology, Chinese Academy of Sciences (Institute of Psychology, Chinese Academy of Sciences) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Funders
- National Natural Science Foundation of China (7171101069, 71771209, KJZDEW-L04, 31170976)
- Chinese Academy of Sciences (KJZD‐EW‐L04)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- gambling behavior, heritability, genetic factors, nonshared environment, shared environment, monozygotic twins, dizygotic twins, gambling addiction, sex differences, age differences, twin studies
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