Metacognitive therapy for adjustment disorder in a patient with newly diagnosed pulmonary arterial hypertension: a case report.
Open accessAbstract
Adjustment disorders (ADs) belong to the worldwide most diagnosed mental disorders and are particularly frequent in patients with an underlying physical illness. Pulmonary arterial hypertension (PAH) is a severe and disabling disease, which significantly impacts on quality of life and has high mortality rates. The authors here present the case of a young female who developed a severe adjustment disorder with both anxious and depressive symptoms after a diagnosis of PAH requiring intensive care treatment due to right heart failure. Psychosocial functioning was severely impaired, and physical health reduced. Following hemodynamic stabilization and the establishment of PAH treatment, the patient was admitted to the Department of Psychiatry, Social Psychiatry and Psychotherapy and received metacognitive therapy (MCT). AD with mixed anxiety and depressed mood was diagnosed according to DSM-V criteria. At the start of treatment, she reported significant mental distress, indicated by a total sum score of the Hospital Anxiety and Depression Scale (HADS) of 20 points. The 6-min walking distance was only 358 m before the patient was exhausted. She then was treated with MCT without further psychopharmacological drugs. After only four MCT sessions, she fully remitted from AD which was accompanied by an 11-point reduction in the HADS (to 9 points). MCT specific scores also improved (MCQ-30 sum score decreased from 77 to 35). Notably, physical capacity improved as well, documented by an improved walking distance (439 m; +22%). This is the first case of a patient with AD in the context of PAH treated with MCT. The case report suggests that MCT is a possible psychotherapeutic treatment option for AD in the context of a potentially life-threatening disease. The study design does not permit an attribution of outcome to MCT but it suggests MCT is a potentially viable and acceptable treatment option.
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This is consistent with studies showing the effectiveness of MCT for patients with somatic diseases that caused or worsened psychiatric disorders.
“This is consistent with studies showing the effectiveness of MCT for patients with somatic diseases that caused or worsened psychiatric disorders (26–28).”
From Metacognitive Short-Term Intervention in Patients With Mental Disorders Following Cardiovascular Events (2022) · cites this paper as [28]
The Case Presentation > Treatment reports reduced anxiety and depression symptoms after MCT in a patient with pulmonary arterial hypertension and adjustment disorder. But the Abstract explicitly says the case-report design does not permit attributing the outcome to MCT; it supports MCT as a possible treatment option, not established effectiveness. (LLM, conf=0.88)
Experimental — accuracy not yet measuredBrief psychological interventions can help patients with CVDs get back into everyday activity.
“some studies have provided promising data, showing, that brief psychological interventions can help patients with CVDs get back into everyday activity (25).”
From Improving mental well-being in psychocardiology—a feasibility trial for a non-blended web application as a brief metacognitive-based intervention in cardiovascular disease patients (2023) · cites this paper as [25]
The Case Presentation > Treatment reports four weekly MCT sessions and a 23% increase in walking distance afterward in one patient with pulmonary arterial hypertension. It does not report a return to everyday activity across patients with cardiovascular diseases; the Abstract also cautions that the study design cannot attribute the improvement to MCT. (LLM, conf=0.86)
Experimental — accuracy not yet measuredPreliminary studies of metacognitive therapy for treating anxiety and depression within physical illnesses show promising evidence.
“Preliminary studies of metacognitive therapy for treating anxiety and depression within physical illnesses show promising evidence [67–69].”
From Metacognitive beliefs and their relationship with anxiety and depression in physical illnesses: A systematic review (2020) · cites this paper as [69]
Initial studies suggest that metacognitive therapy is an acceptable and feasible intervention that was associated with positive outcomes.
“These initial studies suggest that MCT is an acceptable and feasible intervention that was associated with positive outcomes.”
From Metacognitive beliefs and their relationship with anxiety and depression in physical illnesses: A systematic review (2020) · cites this paper as [69]
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Capobianco, L., Faija, C., Husain, Z., & Wells, A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0238457 · Cited by 109 · see citing works
“Winter et al [69] conducted a case study of MCT for adjustment disorder in a patient with pulmonary arterial hypertension.”
BackgroundOlsson, K. M., Meltendorf, T., Fuge, J., Kamp, J. C., Park, D.-H., Richter, M. J., Gall, H., Ghofrani, H. A., Ferrari, P., Schmiedel, R., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.667602 · Cited by 55 · see citing works
Self-citationGebhardt, P., Caldarone, F., Westhoff-Bleck, M., Olsson, K. M., Hoeper, M. M., Park, D.-H., Stapel, B., Breitner, M. H., Werth, O., Heitland, I., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.812807 · Cited by 3 · see citing works
“It has been shown to have the above mentioned attentional effects in anxiety, depression (44) as well as adjustment disorder in a CVD patient (28).”
BackgroundSelf-citationLarionov, K., Petrova, E., Demirbuga, N., Werth, O., Breitner, M. H., Gebhardt, P., Caldarone, F., Duncker, D., Westhoff-Bleck, M., Sensenhauser, A., et al. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1138475 · Cited by 1 · see citing works
“In this context, some studies have provided promising data, showing, that brief psychological interventions can help patients with CVDs get back into everyday activity (25).”
BackgroundSelf-citation
- Authors
- Winter, L., Naumann, F., Olsson, K., Fuge, J., Hoeper, M. M., & Kahl, K. G.
- Affiliations
- Medizinische Hochschule Hannover (DE)
- Corresponding author
- Winter, Lotta
- Venue
- Frontiers in Psychology
- Publisher
- Frontiers Media SA
- Published
- 2020-02-12
- Volume
- 11
- Pages
- 143-143
- ISSN
- 1664-1078 (ISSN-L)
- PMC
- PMC7028769
- OpenAlex
- W3002940278
- Cited by
- 12
- References
- 50
- Citations by year
- 2026: 1 · 2023: 2 · 2022: 7 · 2021: 1 · 2020: 1
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Psychology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Pulmonary Hypertension Research and Treatments
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- metacognitive therapy, adjustment disorder, pulmonary arterial hypertension, anxiety, depression, psychosocial functioning, right heart failure, physical capacity, psychosomatic disorders
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