The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Extracting kinematic parameters for monkey bipedal walking from cortical neuronal ensemble activity
Open accessAbstract
The ability to walk may be critically impacted as the result of neurological injury or disease. While recent advances in brain-machine interfaces (BMIs) have demonstrated the feasibility of upper-limb neuroprostheses, BMIs have not been evaluated as a means to restore walking. Here, we demonstrate that chronic recordings from ensembles of cortical neurons can be used to predict the kinematics of bipedal walking in rhesus macaques - both offline and in real time. Linear decoders extracted 3D coordinates of leg joints and leg muscle electromyograms from the activity of hundreds of cortical neurons. As more complex patterns of walking were produced by varying the gait speed and direction, larger neuronal populations were needed to accurately extract walking patterns. Extraction was further improved using a switching decoder which designated a submodel for each walking paradigm. We propose that BMIs may one day allow severely paralyzed patients to walk again.
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Neuronal ensemble control of prosthetic devices by a human with tetraplegia
Hochberg, L. R., Serruya, M. D., Friehs, G. M., Mukand, J. A., Saleh, M., Caplan, A. H., Branner, A., Chen, D., Penn, R. D., & Donoghue, J. P. (2006) · Nature · doi:10.1038/nature04970 · Cited by 3,295
Brain–machine interfaces: past, present and future
Lebedev, M. A., & Nicolelis, M. A. L. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.07.004 · Cited by 1,875
Self-citationLearning to control a brain–machine interface for reaching and grasping by primates
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Cortical control of a prosthetic arm for self-feeding
Velliste, M., Perel, S., Spalding, M. C., Whitford, A. S., & Schwartz, A. B. (2008) · Nature · doi:10.1038/nature06996 · Cited by 1,591
Brain-Controlled Interfaces: Movement Restoration with Neural Prosthetics
Schwartz, A. B., Cui, X. T., Weber, D. J., & Moran, D. W. (2006) · Neuron · doi:10.1016/j.neuron.2006.09.019 · Cited by 792
Chronic, multisite, multielectrode recordings in macaque monkeys
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Self-citationBiomechanical and physiological aspects of legged locomotion in humans
Saibene, F., & Minetti, A. E. (2003) · European Journal of Applied Physiology · doi:10.1007/s00421-002-0654-9 · Cited by 437
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Cortical mechanisms involved in visuomotor coordination during precision walking
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Wagner, J., Solis-Escalante, T., Grieshofer, P., Neuper, C., Müller-Putz, G., & Scherer, R. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.08.019 · Cited by 301
Sensors and Decoding for Intracortical Brain Computer Interfaces
Homer, M. L., Nurmikko, A. V., Donoghue, J. P., & Hochberg, L. R. (2013) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071910-124640 · Cited by 121
Brain-machine interfaces: an overview.
Lebedev, M. (2014) · Translational Neuroscience · doi:10.2478/s13380-014-0212-z · Cited by 112
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Metadata
- Authors
- Fitzsimmons, N. A.
- Venue
- Frontiers in Integrative Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2009
- Volume
- 3
- Pages
- 3-3
- ISSN
- 1662-5145 (ISSN-L)
- OpenAlex
- W2041098005
- Cited by
- 186
- References
- 9
- FWCI
- 5.33
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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