Sensors and Decoding for Intracortical Brain Computer Interfaces
Open accessAbstract
Intracortical brain computer interfaces (iBCIs) are being developed to enable people to drive an output device, such as a computer cursor, directly from their neural activity. One goal of the technology is to help people with severe paralysis or limb loss. Key elements of an iBCI are the implanted sensor that records the neural signals and the software that decodes the user's intended movement from those signals. Here, we focus on recent advances in these two areas, placing special attention on contributions that are or may soon be adopted by the iBCI research community. We discuss how these innovations increase the technology's capability, accuracy, and longevity, all important steps that are expanding the range of possible future clinical applications.
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- Authors
- Homer, M. L., Nurmikko, A. V., Donoghue, J. P., & Hochberg, L. R.
- Affiliations
- Biomedical Engineering,
- School of Engineering,
- Brown University (US)
- Harvard University (US)
- Venue
- Annual Review of Biomedical Engineering
- Publisher
- Annual Reviews
- Published
- 2013-07-11
- Volume
- 15
- Issue
- 1
- Pages
- 383-405
- ISSN
- 1523-9829 (ISSN-L)
- 1545-4274
- PMC
- PMC3985135
- OpenAlex
- W2165100436
- Cited by
- 121
- References
- 121
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 7 · 2023: 9 · 2022: 10 · 2021: 9 · 2020: 12 · 2019: 7 · 2018: 10 · 2017: 9 · 2016: 16 · 2015: 14 · 2014: 11 · 2012: 1
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annual Review of Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Deafness and Other Communication Disorders (R01DC009899)
- National Institute of Neurological Disorders and Stroke (R01NS025074)
- National Institute of Biomedical Imaging and Bioengineering (R01EB007401)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- intracortical brain-computer interfaces, neural decoding, motor intention decoding, paralysis, neuroprosthetics, clinical translation
- MeSH terms
- Algorithms, Amputation, Surgical, Brain, Calibration, Electrodes, Implanted, Equipment Design, Humans, Paralysis, Signal Processing, Computer-Assisted, Brain-Computer Interfaces
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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