The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Phenolic Compounds and Antimicrobial Activity of Olive (Olea europaea L. Cv. Cobrançosa) Leaves
Open accessAbstract
We report the determination of phenolic compounds in olive leaves by reversed-phase HPLC/DAD, and the evaluation of their in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely gram positive (Bacillus cereus, B. subtilis and Staphylococcus aureus), gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Seven phenolic compounds were identified and quantified: caffeic acid, verbascoside, oleuropein, luteolin 7-O-glucoside, rutin, apigenin 7-O-glucoside and luteolin 4'-O-glucoside. At low concentrations olive leaves extracts showed an unusual combined antibacterial and antifungal action, which suggest their great potential as nutraceuticals, particularly as a source of phenolic compounds.
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“Additionally, in general, in the mixed form, individual components can modify their properties and interact synergistically, producing improved effects [18,25,39].”
From Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea (2020) · cites this paper as [25]
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Cited by
Sorted by citations
Valuable Nutrients and Functional Bioactives in Different Parts of Olive (Olea europaea L.)—A Review
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Metadata
- Authors
- Pereira, A. P., Ferreira, I. C., Marcelino, F., Valentão, P., Andrade, P. B., Seabra, R., Estevinho, L., Bento, A., & Pereira, J. A.
- Affiliations
- Universidade Politécnica de Bragança (PT)
- REQUIMTE / Serviço de Farmacognosia, Faculdade de Farmácia da Universidade do Porto, Rua Aníbal Cunha, 164, 4050-047 Porto, Portugal
- Universidade do Porto (PT)
- CIMO / Escola Superior Agrária, Instituto Politécnico de Bragança, Campus Sta Apolónia, Apt. 1172, 5301-855 Bragança, Portugal
- Corresponding author
- Pereira, José Alberto
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2007-05-26
- Volume
- 12
- Issue
- 5
- Pages
- 1153-1162
- ISSN
- 1420-3049 (ISSN-L)
- PMC
- PMC6149345
- OpenAlex
- W2146146382
- Cited by
- 519
- References
- 26
- Citations by year
- 2026: 16 · 2025: 28 · 2024: 38 · 2023: 19 · 2022: 44 · 2021: 34 · 2020: 46 · 2019: 38 · 2018: 34 · 2017: 33 · 2016: 33 · 2015: 36 · 2014: 29 · 2013: 20 · 2012: 19
- FWCI
- 6.30
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Molecules (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Interreg
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Keywords
- olive leaves, Olea europaea, phenolic compounds, antimicrobial activity, antibacterial activity, antifungal activity, caffeic acid, verbascoside, oleuropein, luteolin glycosides, rutin, apigenin glycosides, nutraceuticals, Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Candida albicans, Cryptococcus neoformans
- MeSH terms
- Anti-Infective Agents, Chromatography, High Pressure Liquid, Microbial Sensitivity Tests, Phenols, Molecular Structure, Plant Leaves, Olea
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