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Cited by 28Protein Hydrolysis and Bioactive PeptidesProteins in Food SystemsChemical Synthesis and Analysis

Food Peptides for the Nutricosmetic Industry

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Dini, Irene, Mancusi, Andrea·2023·Antioxidants
DOI 10.3390/antiox12040788PMC PMC10135249
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Abstract

In recent years, numerous reports have described bioactive peptides (biopeptides)/hydrolysates produced from various food sources. Biopeptides are considered interesting for industrial application since they show numerous functional properties (e.g., anti-aging, antioxidant, anti-inflammatory, and antimicrobial properties) and technological properties (e.g., solubility, emulsifying, and foaming). Moreover, they have fewer side effects than synthetic drugs. Nevertheless, some challenges must be overcome before their administration via the oral route. The gastric, pancreatic, and small intestinal enzymes and acidic stomach conditions can affect their bioavailability and the levels that can reach the site of action. Some delivery systems have been studied to avoid these problems (e.g., microemulsions, liposomes, solid lipid particles). This paper summarizes the results of studies conducted on biopeptides isolated from plants, marine organisms, animals, and biowaste by-products, discusses their potential application in the nutricosmetic industry, and considers potential delivery systems that could maintain their bioactivity. Our results show that food peptides are environmentally sustainable products that can be used as antioxidant, antimicrobial, anti-aging, and anti-inflammatory agents in nutricosmetic formulations. Biopeptide production from biowaste requires expertise in analytical procedures and good manufacturing practice. It is hoped that new analytical procedures can be developed to simplify large-scale production and that the authorities adopt and regulate use of appropriate testing standards to guarantee the population’s safety.

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Authors
Dini, I., & Mancusi, A.
Affiliations
  • University of Naples Federico II (IT)
  • Istituto Zooprofilattico Sperimentale del Mezzogiorno (IT)
Corresponding author
Dini, Irene
ORCID
Venue
Antioxidants
Publisher
MDPI AG
Published
2023-03-23
Volume
12
Issue
4
Pages
788
ISSN
2076-3921 (ISSN-L)
DOI
10.3390/antiox12040788
PMC
PMC10135249
OpenAlex
W4360854807
Cited by
28
References
5
Citations by year
2026: 4 · 2025: 12 · 2024: 10 · 2023: 2
FWCI
0.74
Type
journal article
Language
en
Open access
Licence
Locations
  • Antioxidants (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Chemical Synthesis and Analysis
Keywords
food peptides, bioactive peptides, nutricosmetics, hydrolysate, bioavailability, oral delivery systems, microemulsions, liposomes, solid lipid particles, antioxidant activity, anti-aging, anti-inflammatory agents, antimicrobial activity, biomass waste valorization, marine organisms, plant peptides, functional food ingredients

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