The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review
Open accessAbstract
The consumption of carotenoids has beneficial effects on health, reducing the risk of certain forms of cancer, cardiovascular diseases, and macular degeneration, among others. The mechanism of action of carotenoids has not been clearly identified; however, it has been associated with the antioxidant capacity of carotenoids, which acts against reactive oxygen species and inactivating free radicals, although it has also been shown that carotenoids modulate gene expression. Dietary carotenoids are absorbed and accumulated in the liver and other organs, where they exert their beneficial effects. In recent years, it has been described that the intake of carotenoids can significantly reduce the risk of suffering from liver diseases, such as non-alcoholic fatty liver disease (NAFLD). This disease is characterized by an imbalance in lipid metabolism producing the accumulation of fat in the hepatocyte, leading to lipoperoxidation, followed by oxidative stress and inflammation. In the first phases, the main treatment of NAFLD is to change the lifestyle, including dietary habits. In this sense, carotenoids have been shown to have a hepatoprotective effect due to their ability to reduce oxidative stress and regulate the lipid metabolism of hepatocytes by modulating certain genes. The objective of this review was to provide a description of the effects of dietary carotenoids from fruits and vegetables on liver health.
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Cites
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Cited by
Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process
Michalak, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020585 · Cited by 460
Effect of altitude and harvest year on nutraceutical characteristics of Rubus ellipticus fruits
Dhatwalia, J., Kumari, A., Guleria, I., Kumar Shukla, R., Saleh, N., El-Nashar, H. A. S., & El-Shazly, M. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1419862 · Cited by 16
Metadata
- Authors
- Elvira-Torales, L. I., García-Alonso, J., & Periago-Castón, M. J.
- Venue
- Antioxidants
- Publisher
- MDPI AG
- Published
- 2019-07-19
- Volume
- 8
- Issue
- 7
- Pages
- 229
- ISSN
- 2076-3921 (ISSN-L)
- OpenAlex
- W2962953360
- Cited by
- 219
- References
- 11
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- gold
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