Lactate as a Signaling Molecule That Regulates Exercise-Induced Adaptations

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FGF-21 as a novel metabolic regulator

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Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

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Improved Docking of Polypeptides with Glide

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Hydroxylation of HIF-1: Oxygen Sensing at the Molecular Level

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The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism

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Lactate‐induced metabolic remodeling and myofiber type transitions via activation of the Ca2+‐NFATC1 signaling pathway

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Exerkines: Benign adaptation for exercise and benefits for non-alcoholic fatty liver disease

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Concurrent sprint and aerobic training in swimming: Influence of exercise sequence on physiological responses and perceived exertion

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Serum Metabolites Associated with Muscle Hypertrophy after 8 Weeks of High- and Low-Load Resistance Training

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Physical activity in sarcopenia: rehabilitation approaches in prevention and treatment of age-related muscle disorders

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Optimization of Athlete Recovery Strategies: Analysis of Massage Methods To Determine The Best Approach After High-Intensity Interval Training

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Acute Effects of High-Intensity Resistance Exercise on Recognition of Relational Memory, Lactate, and Serum and Plasma Brain-Derived Neurotrophic Factor

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Pre-ischemic Lactate Levels Affect Post-ischemic Recovery in an Isolated Rat Heart Model of Donation After Circulatory Death (DCD)

Arnold, M., Segiser, A., Graf, S., Méndez‐Carmona, N., Sanz, M. N., Wyss, R. K., Kalbermatter, N., Keller, N., Carrel, T. P., & Longnus, S. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.669205 · Cited by 5

Gallstones: Bad Company for the Steatotic Liver

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The Role of Biomarkers in Elite Sports

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Integrative multi-omics analysis reveals ortho-topolin riboside exhibits anticancer activity by regulating metabolic pathways in radio-resistant triple negative breast cancer cells

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Protective effects of Lactobacillus plantarum strain against protein malnutrition-induced muscle atrophy and bone loss in juvenile mice

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Brief Weekly Magnetic Field Exposure Enhances Avian Oxidative Muscle Character During Embryonic Development

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Effects of inter-set stretching on acute hormonal and metabolic response: a pilot study

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The Comparisons of Blood Lactate Concentration and Removal Rate after Aerobic and Anaerobic Maximal Exercise

Kim, C., Kim, J., Kim, H., Kim, J., Min, S., & Park, D. (2017) · Exercise Science · doi:10.15857/ksep.2017.26.4.239 · Cited by 4

Valores de referencia para las pruebas de Cooper y de 20m de ida y vuelta en población residente en altitud elevada. [Reference values for Cooper and Shuttle Run Tests in population living at high altitude].

Grupo de Investigación Ciencias Aplicadas al Ejercicio, D. Y. S. G., Rojas, I. A. S., Colombia, Romero, D. M., Argüello-Gutiérrez, Y. P., Jiménez, L. E. C., Triana-Reina, H. R., Perez-Cebreros, E. A., Petro, J. L., & Bonilla, D. A. (2021) · RICYDE Revista Internacional de Ciencias del Deporte · doi:10.5232/ricyde2021.06502 · Cited by 4

Remodeling of Cellular Respiration and Insulin Signaling Are Part of a Shared Stress Response in Divergent Bee Species

Rondeau, N. C., Raup-Collado, J., Kogan, H. V., Cho, R. M., Lovinger, N. L., Wague, F., Lopatkin, A. J., Texeira, N. G., Flores, M. E., Rovnyak, D., et al. (2025) · Insects · doi:10.3390/insects16030300 · Cited by 6

Brawn and Brainpower: Acute Resistance Exercise Improves Behavioral and Neuroelectric Measures of Executive Function

Baumgartner, N. W., Belbis, M. D., Noh, K., Hirai, D. M., Amireault, S., & Kao, S. (2025) · Psychophysiology · doi:10.1111/psyp.70171 · Cited by 3

Investigating oral biofluid markers as a tool for the chemometric discrimination of different physical exercise intensities utilizing ATR-FTIR spectroscopy

Chrimatopoulos, C., Chrimatopoulos, G., & Sakkas, V. A. (2023) · Chemometrics and Intelligent Laboratory Systems · doi:10.1016/j.chemolab.2023.104990 · Cited by 3

The growth of mahogany seedlings (Swietenia macrophylla King.) in various planting media and shade intensity

Tanjung, H., Tata, H. L., & Triadiati, T. (2023) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/1271/1/012023 · Cited by 3

Lactate administration induces skeletal muscle synthesis by influencing Akt/ mTOR and MuRF1 in non‐trained mice but not in trained mice

Kyun, S., Kim, J., Hwang, D., Jang, I., Park, H., & Lim, K. (2024) · Physiological Reports · doi:10.14814/phy2.15952 · Cited by 3

Macrophage‐derived extracellular vesicles alter cardiac recovery and metabolism in a rat heart model of donation after circulatory death

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The Impact of Exercise Serum on Selected Parameters of CD4+ T Cell Metabolism

Palmowski, J., Gebhardt, K., Reichel, T., Frech, T., Ringseis, R., Eder, K., Renner-Sattler, K., & Krüger, K. (2021) · Immuno · doi:10.3390/immuno1030008 · Cited by 3

Influence of the Glycemic Index of Pre-exercise Meals in Sports Performance: A Systematic Review

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Effect of Metabolic Stress to High-Load Exercise on Muscle Damage, Inflammatory and Hormonal Responses

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Metabolic and immune links between sarcopenia and liver disease

Kotlyarov, S. N. (2025) · World Journal of Hepatology · doi:10.4254/wjh.v17.i8.109444 · Cited by 2

Glioma neuron symbiosis: a hypothesis

Schurr, A. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1646148 · Cited by 3

Swimming training sets across intensity domains: physiological responses beyond lactate concentration and internal load

Nikitakis, I. S., & Toubekis, A. G. (2025) · European Journal of Applied Physiology · doi:10.1007/s00421-025-06090-9 · Cited by 4

The lactate shuttle in ageing: a metabolic bridge between muscle fatigue and brain resilience

Zhang, Y., Yang, W., & Tian, C. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1823430 · Cited by 2

Chronic Administration of Exogenous Lactate Increases Energy Expenditure during Exercise through Activation of Skeletal Muscle Energy Utilization Capacity in Mice

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Lactato: De vilão a mocinho

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EMG-Based Detection of Minimum Effective Load With Robotic-Resistance Leg Extensor Training

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A Prospective Study of Lactate Levels in Uncomplicated Spontaneous and Induced Labor

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High intensity interval training and its impact on brain-derived neurotrophic factor: a potential mechanism to reduce early onset dementia

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Quantitative Detection of Electrical Impedance Muscle Lactate Based on Residual Graph Attention Network

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Twice-a-day exercise increases acute MCT1 gene expression in skeletal muscle but does not change the lactate curve after 3 weeks of training in adult men

de Mello, A. P. D. F. A. C., Andrade‐Souza, V. A., LEARSI, S. K., Tomazini, F., Ataide‐Silva, T., Kuang, J., Bertuzzi, R., Leandro, C. G., Bishop, D. J., Lima‐Silva, A. E., et al. (2025) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x2025e14500 · Cited by 1

Time-dependent comparison of serum BDNF responses following high-intensity interval exercise and moderate- and low-intensity continuous exercise in healthy young men

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Effects of High-Intensity Interval Training Using the 3/7 Resistance Training Method on Metabolic Stress in People with Heart Failure and Coronary Artery Disease: A Randomized Cross-Over Study

Gillet, A., Forton, K., Lamotte, M., Macera, F., Roussoulieres, A. L. S., Louis, P., Ibrahim, M., Dewachter, C., van de Borne, P., & Deboeck, G. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12247743 · Cited by 1

Modeling Glucose, Insulin, C-Peptide, and Lactate Interplay in Adolescents During an Oral Glucose Tolerance Test

Bonet, J., Barbieri, E., Santoro, N., & Man, C. D. (2024) · Journal of Diabetes Science and Technology · doi:10.1177/19322968241266825 · Cited by 1

Exogenous Lactate Treatment Immediately after Exercise Promotes Glycogen Recovery in Type-II Muscle in Mice

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Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study

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Lactic Acidosis, Metformin Use, and Dose-Response Association

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Qualitative traits of the meat of Nellore steers supplemented with energy and protein in an integrated crop–livestock system

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Corrigendum: Lactate Metabolism and Satellite Cell Fate

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Phenyllactic Acid is Physiologically Released from Skeletal Muscle and Contributes to the Beneficial Effects of Physical Exercise in HumansPreprint

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The effect of whole-body cryotherapy intervention after an exercise on MVIC and ROM of EIMD

Shin, S. P., Son, G. H., & Jeon, J. G. (2020) · The Journal of Korean Academy of Physical Therapy Science · doi:10.26862/jkpts.2020.12.27.3.45

Metabolic reprogramming and redox perturbations

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Análise da resposta metabólica no treinamento de força de alta e baixa intensidade e sua influência sobre a hipertrofia

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An Acute Bout of Exercise Enhances Hypothalamic Leptin Signaling via Central Lactate MetabolismPreprint

Chen, Y., Zhang, S., Ye, L., Chen, H., Yu, L., & Wu, D. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4143299

Pre-running upper body sprint interval training augments endurance running induced aerobic adaptations via lactate. A research proposalPreprint

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Local Metabolic Factors and Vasoactivity

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O EFEITO AGUDO DO FST-7 NO DESEMPENHO, VARIÁVEIS METABÓLICAS E RESPOSTAS PERCEPTIVAS EM HOMENS BEM TREINADOS

Pascoalini, B., Dias, I. B. F., Dias, M. R., Miranda, F., de Souza, A. C. S., Novaes, J. D. S., Vieira, J. G., Junior, R. F. S., & de Salles, B. F. (2022) · Revista Brasileira de Ciência e Movimento · doi:10.31501/rbcm.v29i2.12114

Влияние содержания молочной кислоты в мышцах на выносливость спортсменов

Богачева, Е. В., & Коровенкова, С. В. (2023) · ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ · doi:10.18411/trnio-07-2023-321

Lactate Entrance into the Brain is Necessary for Endurance Exercise-Induced Adaptation in Lipid Oxidation

Aveseh, M., Jahromi, M. K., Nemati, J., & Esmaeili‐Mahani, S. (2023) · Research in Sport Medicine and Technology · doi:10.61186/jsmt.21.25.1

Synthesis and Physicochemical Properties of Yttrium Subgroup REE Lactates Ln(C3H5O3)3·2H2O (Ln = Y, Tb–Lu)

Golikova, M. V., Yapryntsev, A. D., Jia, C., Fatyushina, E. V., Baranchikov, A. E., & Ivanov, V. K. (2023) · Журнал неорганической химии · doi:10.31857/s0044457x23601050

Effects of Extreme Physical and Mental Load on Circulating Exerkines in Professional Athletes

Ligetvári, R. (2024) · Pesci Egyetemi Archivum (University of Pécs) · doi:10.15170/pte.2024.013

LACTATE EFFECTS ON MUSCLE REGENERATION IN VIVO AND IN VITRO MODELS: A SYSTEMATIC REVIEW

Matos, T. F., Carli, M. E. C., de Moraes-Junior, F. B., de Lima, V. A., Mota, J. A. P. S., & Leite, N. (2024) · Revista Brasileira de Medicina do Esporte · doi:10.47870/1517-8692202531012021_0325i

EFEITO DO LACTATO NA REGENERAÇÃO MUSCULAR EM MODELOS IN VIVO E IN VITRO: UMA REVISÃO SISTEMÁTICA

Matos, T. F., Carli, M. E. C., de Moraes-Junior, F. B., de Lima, V. A., Mota, J. A. P. S., & Leite, N. (2024) · Revista Brasileira de Medicina do Esporte · doi:10.47870/1517-8692202531012021_0325p

Exploring the Effect of Attachment Position of Electrodes for EMG-Based Detection of Minimum Effective Load on Muscles

Miyake, T., & Sugano, S. (2025) · IEEE/SICE International Symposium on System Integration (SII) · doi:10.1109/sii59315.2025.10870907

Lactate in Anaphylaxis: 100 Years On

Borzova, E. Y., & Gibbs, B. F. (2025) · Sports Medicine · doi:10.1007/s40279-025-02273-8

METABOLIC CHANGES AND ENERGY SUPPLY MECHANISMS OCCURRING IN THE BODY DURING SPORTS ACTIVITY: ROLE OF ANAEROBIC AND AEROBIC PROCESSES

Yusifov, G. D., Khalilli, M. H., Hacımammadova, S. I., & Agayeva, S. R. (2025) · Scientific News of Academy of Physical Education and Sport · doi:10.28942/ssj.v7i2.879

Remote ischemic preconditioning enhances renal function recovery after ischemia-reperfusion injury: potential role of lactate as a mediatorPreprint

Akbari, Z., Fatemikia, H., Karimi, Z., Tanha, K., Assadi, M., & Pourkhalili, K. (2025) · Research Square · doi:10.21203/rs.3.rs-7856193/v1

Blood Biochemical Responses to Acute Exercise: Findings from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)Preprint

Robbins, J., Katz, D. H., Many, G. M., Rao, P., Smith, G. R., Tiwari, G., Jin, C. A., Spielmann, G., Montalvo, S., Iyer, G. R., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.02.704798 · Cited by 2

Effect of Aerobic Exercise and a Diet Supplementation with Linoleic Acid on Metabolic Parameters in Drosophila melanogaster

Alves, T. H. O., Silva, J. R., Limeira, I. M., Rhein, S. O., & Souza, A. O. (2026) · Biology · doi:10.3390/biology15080607

Advances in near-infrared fluorescent probes for the tumor microenvironment

Hu, H., Zhang, C., Kong, X., Chen, Y., & Chen, R. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-08240-9

Effects of single sodium bicarbonate supplementation versus co-ingestion with beta-alanine, creatine, or caffeine on anaerobic performance, buffering capacity, and perceived fatigue: a systematic review and meta-analysis

Eidiyan-Kakhki, M. M., Nikolaidis, P. Τ., Willems, M. E. T., Clemente, F. M., رجبی, ح., Amani-Shalamzari, S., Motamedi, P., Salehpour, M., & Samadi, H. (2026) · Sport Sciences for Health · doi:10.1007/s11332-026-01813-7

Lactate signalling, exercise and neuroenergetic resilience in cancer supportive care: implications for fatigue, cognition, survivorship and lactylation

Zhang, Z.-W., Zhou, Y., Dong, H.-M., Kong, J., Chen, B.-A., Chen, H.-B., & Wang, R.-C. (2026) · Psycho-Oncologie · doi:10.18282/po5898

The lactate–HCAR1 axis in exercise psychiatry: a candidate mechanism linking bone marrow–brain immunity to inflammation-related depression

Luan, C., Lei, C., & Liu, M. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1871773

Divergent metabolic and immunoepigenetic responses in LPS-induced endotoxemia: a dose optimization study in male BALB/c mice

Prawira, Y., Malik, S. G., Munasir, Z., Widyahening, I. S., Dewi, R., Alam, A., & Pudjiadi, A. H. (2026) · Immunological Medicine · doi:10.1080/25785826.2026.2715167

Influence of blood flow restriction cuff width on acute metabolic, perceptual, and landing responses to low-load resistance exercise in trained long jump athletes

Wang, C., & Yang, H. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1912080

Architects of Aggression: The Molecular Blueprint of Glioma Progression

Aebisher, D., Tylutki, J., Myśliwiec, A., Kozak, N., & Bartusik‐Aebisher, D. (2026) · Genes · doi:10.3390/genes17091120

Acute neurotrophic responses to a single bout of blood flow restriction and eccentric overload exercise in healthy older men

Qipo, O., Bautmans, I., Vints, W. A. J., Njemini, R., Mickevičienė, L., Česnaitienė, V. J., Levin, O., & Masiulis, N. (2026) · GeroScience · doi:10.1007/s11357-026-02601-4

New insights into lactate in exercise adaptations: does protein lactylation play a role?

Wang, Z., & Zhu, L. (2025) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00225.2025 · Cited by 17

Is Lactate a Signaling Molecule (A ‘Lactormone’)?

Machado, M. (2022) · RePEc: Research Papers in Economics

Lactate as a signaling molecule : A potential role in controlling exercise induced adaptations in human skeletal muscle

Nordström, F. (2021) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Reply to ‘Lactate as a major myokine and exerkine’

Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S. W., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., et al. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00726-y · Cited by 5

Editorial: Lactate as a Major Signaling Molecule for Homeostasis

Pellerin, L., Connes, P., Bisbal, C., & Lambert, K. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.910567 · Cited by 8