Cited by 3,683Muscle Physiology and DisordersAdipose Tissue and MetabolismMuscle metabolism and nutrition

SATELLITE CELL OF SKELETAL MUSCLE FIBERS

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Mauro, Alexander·1961·The Journal of Cell Biology

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Crossref · 10.1083/jcb.9.2.493

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  • When aged and young MuSCs are compared in equivalent in vivo repair settings, aged MuSCs show intrinsic changes that reduce self-renewal and repair capacity.

    “The prospective isolation methods described above enabled recent findings demonstrating that MuSCs from aged tissues accumulate intrinsic changes that lead to a reduction in self-renewal and repair capacity, relative to young tissues, when placed in equivalent in vivo repair settings22,25,29,55,56 (Fig. 3).”
  • Muscle regeneration is primarily mediated by muscle stem cells or satellite cells (SCs), which reside in a characteristic niche located between the basal lamina and plasma membrane of myofibers.

    “Muscle regeneration is primarily mediated by muscle stem cells or satellite cells (SCs), which reside in a characteristic niche located between the basal lamina and plasma membrane of myofibers12.”

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Authors
Mauro, A.
Affiliations
Rockefeller University (US)
Corresponding author
Mauro, Alexander
Venue
The Journal of Cell Biology
Published
1961-02-01
Volume
9
Issue
2
Pages
493-495
ISSN
  • 0021-9525 (ISSN-L)
  • 1540-8140
OpenAlex
W2087803244
Cited by
3,683
References
1
Citations by year
2026: 72 · 2025: 96 · 2024: 114 · 2023: 119 · 2022: 154 · 2021: 176 · 2020: 177 · 2019: 151 · 2018: 166 · 2017: 153 · 2016: 148 · 2015: 159 · 2014: 161 · 2013: 152 · 2012: 170
FWCI
1.69
Type
journal article
Language
en
Open access
Locations
  • The Journal of Cell Biology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Science Foundation
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
  • Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
Keywords
satellite cells, skeletal muscle fibers, muscle regeneration, myogenesis, muscle stem cells
MeSH terms
Muscles, Muscle Fibers, Skeletal, Myoblasts

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