Fighting against Skin Aging: The Way from Bench to Bedside

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

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Inflamm‐aging: An Evolutionary Perspective on Immunosenescence

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H ₂ O ₂ , a Necessary Evil for Cell Signaling

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Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light

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Molecular basis of sun-induced premature skin ageing and retinoid antagonism

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Oxidative Stress in Aging Human Skin

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Direct and indirect effects of UV radiation on DNA and its components

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Oxidation events and skin aging

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Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

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Epidermal Stem Cells of the Skin

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Role of antioxidants in the skin: Anti-aging effects

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The skin aging exposome

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A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

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Skin hydration: A review on its molecular mechanisms

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Natural and Sun-Induced Aging of Human Skin

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Molecular aspects of skin ageing

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Restoration of Collagen Formation in Photodamaged Human Skin by Tretinoin (Retinoic Acid)

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Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

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Skin ageing

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Chemical inhibition of NAT10 corrects defects of laminopathic cells

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N‐acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities

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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

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Early Destructive Effect of Sunlight on Human Skin

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Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson–Gilford progeria syndrome

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Ultraviolet Radiation‐Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin Aging

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High oxidative damage levels in the longest‐living rodent, the naked mole‐rat

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Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells

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Inhibition of Type I Procollagen Synthesis by Damaged Collagen in Photoaged Skin and by Collagenase-Degraded Collagen in Vitro

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Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations

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Age-dependent accumulation of N.epsilon.-(carboxymethyl)lysine and N.epsilon.-(carboxymethyl)hydroxylysine in human skin collagen

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Molecular Mechanisms of Skin Aging

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Evidence supporting antioxidant action of adipose-derived stem cells: Protection of human dermal fibroblasts from oxidative stress

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Changes Associated with the Aging Face

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Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

Yang, W., & Hekimi, S. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00571.x · Cited by 251 · see citing works

Improvement of Skin Quality after Fat Grafting: Clinical Observation and an Animal Study

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Improvement of Naturally Aged Skin With Vitamin A (Retinol)

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Adipose-Derived Stem Cells and Their Secretory Factors as a Promising Therapy for Skin Aging

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Reduced Expression of Connective Tissue Growth Factor (CTGF/CCN2) Mediates Collagen Loss in Chronologically Aged Human Skin

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Antioxidant supplements and mortality

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Long-term sun exposure alters the collagen of thepapillary dermis

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Early Mitochondrial Dysfunction in Long-lived Mclk1+/- Mice

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A histological study of human wrinkle structures: comparison between sun-exposed areas of the face, with or without wrinkles, and sun-protected areas

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Anti-Inflammation Activities of Mycosporine-Like Amino Acids (MAAs) in Response to UV Radiation Suggest Potential Anti-Skin Aging Activity

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Intrinsic skin aging: the role of oxidative stress.

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Characteristics and Pathomechanisms of Endogenously Aged Skin

Makrantonaki, E., & Zouboulis, C. C. (2007) · Dermatology · doi:10.1159/000100890 · Cited by 177 · see citing works

Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome

Gordon, L. B., Kleinman, M. E., Massaro, J., D’Agostino, R. B., Shappell, H. M., Gerhard‐Herman, M. D., Smoot, L. B., Gordon, C. M., Cleveland, R., Nazarian, A., et al. (2016) · Circulation · doi:10.1161/circulationaha.116.022188 · Cited by 166 · see citing works

Inhibition of Protein Glycation by Extracts of Culinary Herbs and Spices

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Photoaging. Manifestations, prevention, and treatment.

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Photoaging: Manifestations, Prevention, and Treatment

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Molecular-level insights into aging processes of skin elastin

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Vimentin Is the Specific Target in Skin Glycation

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Inflammaging in Skin and Other Tissues - The Roles of Complement System and Macrophage

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Ageing and microvasculature

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Antioxidant Induces DNA Damage, Cell Death and Mutagenicity in Human Lung and Skin Normal Cells

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Sulforaphane enhances progerin clearance in H utchinson– G ilford progeria fibroblasts

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Molecular insights into the premature aging disease progeria

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Ultraviolet B Wavelength Dependence for the Regulation of Two Major Matrix‐Metalloproteinases and Their Inhibitor TIMP‐1 in Human Dermal Fibroblasts

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The role of telomeres in the ageing of human skin: Telomeres and skin ageing

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Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice

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Anti-Aging Effect of Adipose-Derived Stem Cells in a Mouse Model of Skin Aging Induced by D-Galactose

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Nutrition and aging skin: Sugar and glycation

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Comparison of endothelial function, O2−· and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice

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Genetics and skin aging

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Monocyte Induction of IL-10 and Down-Regulation of IL-12 by iC3b Deposited in Ultraviolet-Exposed Human Skin

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Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective

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Extrinsic aging: UV-mediated skin carcinogenesis

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Active induction of unresponsiveness (tolerance) to DNFB by in vivo ultraviolet-exposed epidermal cells is dependent upon infiltrating class II MHC+ CD11bbright monocytic/macrophagic cells.

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Anti-skin-aging effect of epigallocatechin gallate by regulating epidermal growth factor receptor pathway on aging mouse model induced by d -Galactose

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Superficial Enhanced Fluid Fat Injection (SEFFI) to Correct Volume Defects and Skin Aging of the Face and Periocular Region

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miR-23a-3p Causes Cellular Senescence by Targeting Hyaluronan Synthase 2: Possible Implication for Skin Aging

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Aging, low-grade systemic inflammation and vitamin D: a mini-review

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Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres

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The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging

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A high-content imaging-based screening pipeline for the systematic identification of anti-progeroid compounds

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Nε-(Carboxymethyl)lysine Modification of Elastin Alters Its Biological Properties: Implications for the Accumulation of Abnormal Elastic Fibers in Actinic Elastosis

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Decreased expression of keratinocyte beta1 integrins in chronically sun-exposed skin in vivo

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The process of ageing reflected by histological changes in the skin.

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DNA damage responses in skin biology—Implications in tumor prevention and aging acceleration

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Skin Rejuvenation and Volume Enhancement with the Micro Superficial Enhanced Fluid Fat Injection (M-SEFFI) for Skin Aging of the Periocular and Perioral Regions

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Analyses of changes on skin by aging

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Mathematical morphologic analysis of aging-related epidermal changes.

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Prevention of DNA damage in human skin by topical sunscreens

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MicroRNAs in human skin ageing

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Effect of Micronutrients on Methylglyoxal-Mediated In Vitro Glycation of Albumin

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Progeroid Syndromes and UV-Induced Oxidative DNA Damage

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In serum veritas—in serum sanitas? Cell non-autonomous aging compromises differentiation and survival of mesenchymal stromal cells via the oxidative stress pathway

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UVA- and UVB-induced changes in hairless mouse skin collagen

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Sugar Sag: Glycation and the Role of Diet in Aging Skin.

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Anticedants and natural prevention of environmental toxicants induced accelerated aging of skin

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Adipose-Derived Stem Cell to Epithelial Stem Cell Transdifferentiation: A Mechanism to Potentially Improve Understanding of Fat Grafting's Impact on Skin Rejuvenation

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iC3b Arrests Monocytic Cell Differentiation Into CD1c-Expressing Dendritic Cell Precursors: A Mechanism for Transiently Decreased Dendritic Cells in vivo After Human Skin Injury by Ultraviolet B

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UVB-Induced Melanocyte Proliferation in Neonatal Mice Driven by CCR2-Independent Recruitment of Ly6clowMHCIIhi Macrophages

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