Cited by 2,720Curcumin's Biomedical ApplicationsPhytochemicals and Antioxidant ActivitiesSaffron Plant Research Studies

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Curcumin: A Review of Its Effects on Human Health

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Hewlings, Susan, Kalman, Douglas·2017·Foods

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Abstract

Turmeric, a spice that has long been recognized for its medicinal properties, has received interest from both the medical/scientific world and from culinary enthusiasts, as it is the major source of the polyphenol curcumin. It aids in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and performance in active people. In addition, a relatively low dose of the complex can provide health benefits for people that do not have diagnosed health conditions. Most of these benefits can be attributed to its antioxidant and anti-inflammatory effects. Ingesting curcumin by itself does not lead to the associated health benefits due to its poor bioavailability, which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination. There are several components that can increase bioavailability. For example, piperine is the major active component of black pepper and, when combined in a complex with curcumin, has been shown to increase bioavailability by 2000%. Curcumin combined with enhancing agents provides multiple health benefits. The purpose of this review is to provide a brief overview of the plethora of research regarding the health benefits of curcumin.

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Authors: Hewlings, S., & Kalman, D.
Affiliations: Central Michigan University (US)
Nova Southeastern University (US)
Corresponding author: Hewlings, Susan
ORCID: Hewlings, Susan
Kalman, Douglas
Venue: Foods
Publisher: MDPI AG
Published: 2017-10-22
Volume: 6
Issue: 10
Pages: 92
ISSN: 2304-8158 (ISSN-L)
DOI: 10.3390/foods6100092
PMC: PMC5664031
OpenAlex: W2766083858
Cited by: 2,720
References: 68
Citations by year: 2026: 336 · 2025: 364 · 2024: 383 · 2023: 399 · 2022: 415 · 2021: 380 · 2020: 258 · 2019: 125 · 2018: 54 · 2017: 1
FWCI: 7.72
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Foods (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Curcumin's Biomedical Applications
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Saffron Plant Research Studies
Keywords: curcumin, turmeric, polyphenols, bioavailability, piperine, antioxidant activity, anti-inflammatory activity, oxidative stress, metabolic syndrome, arthritis, anxiety, hyperlipidemia, exercise-induced inflammation, muscle soreness, post-exercise recovery

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Curcumin: A Review of Its Effects on Human Health

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