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Cited by 256

The DOI matches its Crossref record; 182 of the 182 references it cites were found in a registry or an index.

Nanoparticles and Controlled Delivery for Bioactive Compounds: Outlining Challenges for New “Smart-Foods” for Health

Open access
Martínez-Ballesta, MCarment, Gil-Izquierdo, Ángel, García-Viguera, Cristina, Domínguez-Perles, Raúl·2018·Foods

Abstract

Nanotechnology is a field of research that has been stressed as a very valuable approach for the prevention and treatment of different human health disorders. This has been stressed as a delivery system for the therapeutic fight against an array of pathophysiological situations. Actually, industry has applied this technology in the search for new oral delivery alternatives obtained upon the modification of the solubility properties of bioactive compounds. Significant works have been made in the last years for testing the input that nanomaterials and nanoparticles provide for an array of pathophysiological situations. In this frame, this review addresses general questions concerning the extent to which nanoparticles offer alternatives that improve therapeutic value, while avoid toxicity, by releasing bioactive compounds specifically to target tissues affected by specific chemical and pathophysiological settings. In this regard, to date, the contribution of nanoparticles to protect encapsulated bioactive compounds from degradation as a result of gastrointestinal digestion and cellular metabolism, to enable their release in a controlled manner, enhancing biodistribution of bioactive compounds, and to allow them to target those tissues affected by biological disturbances has been demonstrated.

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Crossref · 10.3390/foods7050072

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Metadata

Authors
Martínez-Ballesta, M., Gil-Izquierdo, Á., García-Viguera, C., & Domínguez-Perles, R.
Venue
Foods
Publisher
MDPI AG
Published
2018-05-07
Volume
7
Issue
5
Pages
72
ISSN
2304-8158 (ISSN-L)
OpenAlex
W2801521087
Cited by
256
References
182
FWCI
19.62
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Nanoparticles and Controlled Delivery for Bioactive Compounds: Outlining Challenges for New “Smart-Foods” for Health. https://app.cochat.ai/papers/10.3390/foods7050072
The paper
Martínez-Ballesta, M., Gil-Izquierdo, Á., García-Viguera, C., & Domínguez-Perles, R. (2018). Nanoparticles and Controlled Delivery for Bioactive Compounds: Outlining Challenges for New “Smart-Foods” for Health. Foods. https://doi.org/10.3390/foods7050072

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