The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Effects and Mechanisms of Phthalates’ Action on Reproductive Processes and Reproductive Health: A Literature Review
Open accessAbstract
The production of plastic products, which requires phthalate plasticizers, has resulted in the problems for human health, especially that of reproductive health. Phthalate exposure can induce reproductive disorders at various regulatory levels. The aim of this review was to compile the evidence concerning the association between phthalates and reproductive diseases, phthalates-induced reproductive disorders, and their possible endocrine and intracellular mechanisms. Phthalates may induce alterations in puberty, the development of testicular dysgenesis syndrome, cancer, and fertility disorders in both males and females. At the hormonal level, phthalates can modify the release of hypothalamic, pituitary, and peripheral hormones. At the intracellular level, phthalates can interfere with nuclear receptors, membrane receptors, intracellular signaling pathways, and modulate gene expression associated with reproduction. To understand and to treat the adverse effects of phthalates on human health, it is essential to expand the current knowledge concerning their mechanism of action in the organism.
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The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
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Calcium Control of Neurotransmitter Release
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Cited by
Human skin absorption of three phthalates
Hopf, N. B., De Luca, H. P., Borgatta, M., Koch, H. M., Pälmke, C., Benedetti, M., Berthet, A., & Reale, E. (2024) · Toxicology Letters · doi:10.1016/j.toxlet.2024.05.016 · Cited by 24
Evaluating additive release from conventional and biodegradable mulch films
Scopetani, C., Bellabarba, A., Selvolini, G., Martellini, T., Viti, C., & Cincinelli, A. (2025) · Science of The Total Environment · doi:10.1016/j.scitotenv.2025.179294 · Cited by 15
Özel, F., Stratmann, M., Lindh, C., Gennings, C., Bornehag, C.-G., & Rüegg, J. (2023) · Environment International · doi:10.1016/j.envint.2023.108029 · Cited by 11
Maternal Lifestyle During Pregnancy and Its Influence on Offspring’s Telomere Length
Vakonaki, E., Vitiadou, M. T., Panteris, E., Tzatzarakis, M., Tsatsakis, A., & Hatzidaki, E. (2025) · Life · doi:10.3390/life15081250 · Cited by 6
Metadata
- Authors
- Hlisníková, H., Petrovičová, I., Kolena, B., Šidlovská, M., & Sirotkin, A.
- Venue
- International Journal of Environmental Research and Public Health
- Publisher
- MDPI AG
- Published
- 2020-09-18
- Volume
- 17
- Issue
- 18
- Pages
- 6811
- ISSN
- 1660-4601 (ISSN-L)
- OpenAlex
- W3087422157
- Cited by
- 331
- References
- 10
- FWCI
- 10.53
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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