Cited by 252Seaweed-derived Bioactive CompoundsMarine Sponges and Natural ProductsMarine and coastal plant biology

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Bioactivities from Marine Algae of the Genus Gracilaria

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De Almeida, Cynthia Layse F., De S. Falcão, Heloina, De M. Lima, Gedson R., De A. Montenegro, Camila, Lira, Narlize S., De Athayde-Filho, Petrônio F., Rodrigues, Luis C., De Souza, Maria de Fátima V., Barbosa-Filho, José M., Batista, Leônia M.·2011·International Journal of Molecular Sciences

DOI 10.3390/ijms12074550PMC PMC3155369

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Abstract

Seaweeds are an important source of bioactive metabolites for the pharmaceutical industry in drug development. Many of these compounds are used to treat diseases like cancer, acquired immune-deficiency syndrome (AIDS), inflammation, pain, arthritis, as well as viral, bacterial, and fungal infections. This paper offers a survey of the literature for Gracilaria algae extracts with biological activity, and identifies avenues for future research. Nineteen species of this genus that were tested for antibacterial, antiviral, antifungal, antihypertensive, cytotoxic, spermicidal, embriotoxic, and anti-inflammatory activities are cited from the 121 references consulted.

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Authors: De Almeida, C. L. F., De S. Falcão, H., De M. Lima, G. R., De A. Montenegro, C., Lira, N. S., De Athayde-Filho, P. F., Rodrigues, L. C., De Souza, M. D. F. V., Barbosa-Filho, J. M., & Batista, L. M.
Affiliations: Department of Pharmaceutical Sciences, Laboratory of Pharmaceutical Technology, Federal University of Paraiba, João Pessoa, PB 58051-900, Brazil
Universidade Federal da Paraíba (BR)
Corresponding author: Batista, Leônia M.
ORCID: Batista, Leônia M.
Venue: International Journal of Molecular Sciences
Publisher: MDPI AG
Published: 2011-07-15
Volume: 12
Issue: 7
Pages: 4550-4573
ISSN: 1422-0067 (ISSN-L)
DOI: 10.3390/ijms12074550
PMC: PMC3155369
OpenAlex: W2080981798
Cited by: 252
References: 113
Citations by year: 2026: 8 · 2025: 14 · 2024: 15 · 2023: 21 · 2022: 31 · 2021: 23 · 2020: 16 · 2019: 28 · 2018: 17 · 2017: 10 · 2016: 13 · 2015: 17 · 2014: 10 · 2013: 13 · 2012: 13
FWCI: 1.22
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (vor)
Locations: International Journal of Molecular Sciences (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Fundação de Apoio à Pesquisa do Estado da Paraíba
Topics: Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
Keywords: Gracilaria, red algae, marine algae, bioactive metabolites, antibacterial activity, antiviral activity, antifungal activity, antihypertensive effect, cytotoxicity, spermicidal activity, embryotoxicity, anti-inflammatory activity, drug development
MeSH terms: Animals, Anti-Infective Agents, Anti-Inflammatory Agents, Anticonvulsants, Bacteria, Cell Survival, DNA Viruses, Fungi, Humans, Nervous System, Plant Extracts, Platelet Aggregation, RNA Viruses, Gracilaria

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