Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells

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p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

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Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

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Isolation of multipotent adult stem cells from the dermis of mammalian skin

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Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche

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HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

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Ultraviolet Radiation‐Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin Aging

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Bioprinting: From Tissue and Organ Development to in Vitro Models

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Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells

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Embryonic skin development and repair

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Skin equivalents: skin from reconstructions as models to study skin development and diseases

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The Importance of Mimicking Dermal-Epidermal Junction for Skin Tissue Engineering: A Review

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Developing a sense of touch

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Bioengineered skin organoids: from development to applications

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Reprogramming of three-dimensional microenvironments for in vitro hair follicle induction

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Roles of the Glucocorticoid and Mineralocorticoid Receptors in Skin Pathophysiology

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Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium

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An Ectoderm-Derived Myeloid-like Cell Population Functions as Antigen Transporters for Langerhans Cells in Zebrafish Epidermis

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Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation

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Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling

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Protein biomarker for psoriasis: A systematic review on their role in the pathomechanism, diagnosis, potential targets and treatment of psoriasis

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Signaling pathways regulating ectodermal cell fate choices

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Keratin expression by corneal and limbal stem cells during development

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Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

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Keratins in Skin Epidermal Development and Diseases

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Hippo‐Yap/Taz signaling: Complex network interactions and impact in epithelial cell behavior

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The Role of Stem Cells in Aesthetic Surgery

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Beyond 2D: 3D bioprinting for skin regeneration

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Wnt Signaling Pathways in Keratinocyte Carcinomas

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Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives

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The applications of 3D printing in wound healing: The external delivery of stem cells and antibiosis

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Organoid‐Guided Precision Medicine: From Bench to Bedside

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2A-DUB/Mysm1 Regulates Epidermal Development in Part by Suppressing p53-Mediated Programs

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Patterning and morphogenesis of the intricate but stereotyped oikoplastic epidermis of the appendicularian, Oikopleura dioica

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Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo

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Development and Maintenance of Epidermal Stem Cells in Skin Adnexa

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Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

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Role of Protein Phosphatase 2A in Osteoblast Differentiation and Function

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Exploring differentially expressed genes between anagen and telogen secondary hair follicle stem cells from the Cashmere goat (Capra hircus) by RNA-Seq

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Wnt signaling in skin homeostasis and pathology

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Exogenous R-Spondin1 Induces Precocious Telogen-to-Anagen Transition in Mouse Hair Follicles

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YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate

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Skin appendage-derived stem cells: cell biology and potential for wound repair

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Skin Development and Disease: A Molecular Perspective

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Differentiation of pluripotent stem cells for modeling human skin development and potential applications

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Application of Organoids in Regenerative Medicine

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Retinoic acid signalling in the development of the epidermis, the limbs and the secondary palate

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Senescence of human skin-derived precursors regulated by Akt-FOXO3-p27KIP1/p15INK4b signaling

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Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis

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Optical Studies of Nanodiamond-Tissue Interaction: Skin Penetration and Localization

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Granzyme B in epithelial barrier dysfunction and related skin diseases

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IRF6 and AP2A Interaction Regulates Epidermal Development

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Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin

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Advances in engineered organoid models of skin for biomedical research

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Signaling Molecules Governing Pluripotency and Early Lineage Commitments in Human Pluripotent Stem Cells.

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Idiopathic facial aseptic granuloma: case report and literature review

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Conditional knockout in mice reveals the critical roles of Ppp2ca in epidermis development

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The role of Sox9 in maintaining the characteristics and pluripotency of Arbas Cashmere goat hair follicle stem cells

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Genetic analysis of Ras genes in epidermal development and tumorigenesis

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Divergent functions of histone acetyltransferases KAT2A and KAT2B in keratinocyte self-renewal and differentiation

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Cytokeratin Expression at Different Stages in Sweat Gland Development of C57BL/6J Mice

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Role of Actin Cytoskeleton in the Regulation of Epithelial Cutaneous Stem Cells

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Germline soma communication mediated by gap junction proteins regulates epithelial morphogenesis

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Expansion of Hair Follicle Stem Cells Sticking to Isolated Sebaceous Glands to Generate in Vivo Epidermal Structures

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Xenopus: An in vivo model for studying skin response to ultraviolet B irradiation

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Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis

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Spatiotemporal Expression of p63 in Mouse Epidermal Commitment

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Epithelial dynamics shed light on mechanisms underlying ear canal defects

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Au nanostar nanoparticle as a bio-imaging agent and its detection and visualization in biosystems

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Ontogeny of Skin Stem Cells and Molecular Underpinnings

Dermitzakis, I., Kampitsi, D. D., Μanthou, M. E., Evangelidis, P., Vakirlis, E., Meditskou, S., & Theotokis, P. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46080481 · Cited by 8

Novel Approaches for the Application of Herbs for Skin Care

Gautam, R. K., Kamal, M. A., Chopra, H., Tsagkaris, C., & Matthews, L. (2022) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201023666220411110358 · Cited by 7

Generating iPSCs with a High-Efficient, Non-Invasive Method—An Improved Way to Cultivate Keratinocytes from Plucked Hair for Reprogramming

Wüstner, L.-S., Klingenstein, M., Frey, K. G., Nikbin, M. R., Milazzo, A., Kleger, A., Liebau, S., & Klingenstein, S. (2022) · Cells · doi:10.3390/cells11121955 · Cited by 7

Xenopus as a model system for studying pigmentation and pigmentary disorders

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N-Acetylcysteine modulates the effects of composites on human gingival keratinocytes

Siemer, K., Husari, A., Vach, K., Tomakidi, P., Hellwig, E., Schulz, S., & Polydorou, O. (2021) · Dental Materials · doi:10.1016/j.dental.2021.01.011 · Cited by 6

The combined effects of Map3k1 mutation and dioxin on differentiation of keratinocytes derived from mouse embryonic stem cells

Wang, J., Xiao, B., Kimura, E., Mongan, M., & Xia, Y. (2022) · Scientific Reports · doi:10.1038/s41598-022-15760-z · Cited by 6

Dissociative and Nondissociative Models for Culture of Human Eccrine Glands for Toxicology Testing and Tissue Engineering Applications

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Getting out of a mammalian egg: the egg tooth and caruncle of the echidna

Fenelon, J. C., Bennetts, A., Anthwal, N., Pyne, M. J., Johnston, S. D., Evans, A. R., Tucker, A. S., & Renfree, M. B. (2022) · Developmental Biology · doi:10.1016/j.ydbio.2022.12.005 · Cited by 5

Targeted deletion of Ruvbl1 results in severe defects of epidermal development and perinatal mortality

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Toward Understanding Wound Immunology for High-Fidelity Skin RegenerationPreprint

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Exploring the Active Constituents of Andrographis paniculata in Protecting the Skin Barrier and the Synergistic Effects with Collagen XVII

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IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia

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Glucocorticoid Receptor Signaling in Skin Barrier Function

Sevilla, L. M., & Pérez, P. (2018) · IntechOpen eBooks · doi:10.5772/intechopen.79458 · Cited by 4

Rat Hepatocellular Primary Cells: A Cellular and Genetic Assessment of the Chitosan Nanoparticles-Induced Damage and Cytotoxicity.

Alkhafaji, R. S., Khalfa, H. M., & AL-Msaid, H. L. F. (2022) · PubMed Central · doi:10.22092/ari.2022.357103.1974 · Cited by 4

The effect of Wharton’s jelly-derived stem cells seeded/boron-loaded acellular scaffolds on the healing of full-thickness burn wounds in the rat model

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Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis

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Distribution of Vernix Caseosa and Associated Factors Among Newborns Delivered at Adama Comprehensive Specialized Hospital Medical College, Ethiopia, in 2022: Cross-Sectional Study

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Anatomie et physiologie du cheveu humain

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Kinetics of the maintenance of the epidermis

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Anatomy and Biology of Hair at Different Ages

Pélissier‐Alicot, A. (2023) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781837671946-00001 · Cited by 2

The effect of acellular scaffold loaded with Wharton’s jelly-derived stem cells and mineral pitch on healing of burn model in rat

Boukani, L. M., Ezzati, M., Khosroshahi, A. F., & Kheirjou, R. (2024) · Cell and Tissue Banking · doi:10.1007/s10561-024-10143-2 · Cited by 3

Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation

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DNA repair during embryonic epidermal stratification

Meguro, F., Kawasaki, K., Kakihara, Y., Kawasaki, M., Fukushima, M., Sari, F. T., Utama, V., Kesuma, A., Nihara, J., Kudo, T., et al. (2025) · Developmental Dynamics · doi:10.1002/dvdy.70046 · Cited by 1

Protein targets & therapeutics in psoriasis: toward personalization

Shaikh, M. A., Haque, Z., Haque, A., Kumar, S., & Taleuzzaman, M. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115331 · Cited by 1

Wnt‐Signalwege bei kutaner Homöostase und Pathologie

Augustin, I. (2015) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/ddg.12620_suppl · Cited by 1

Skin Organogenesis and Dysmorphogenetic Factors in Skin Diseases (Review)

Yaglova, N. V., Obernikhin, S. S., Tsomartova, D. A., Ivanova, M. J., Kartashkina, N. L., & Васильевна, Ч. Е. (2018) · Современные технологии в медицине · doi:10.17691/stm2018.10.4.23 · Cited by 1

FOXO4-SP6 axis controls surface epithelium commitment by mediating epigenomic remodeling

Liu, J., Huang, H., An, F., Wu, S., Guo, H., Wang, B., Han, Z., Tan, J., Lin, Z., Fang, Y., et al. (2025) · Stem Cell Reports · doi:10.1016/j.stemcr.2025.102445 · Cited by 1

Cellular genetic expression of purinergic receptors in different organs of male rats injected with cyclophosphoamide

Khalfa, H. M., AL-Msaid, H. L. F., Abood, A. H., Naji, M. A., & Hussein, S. K. (2020) · AIP conference proceedings · doi:10.1063/5.0027389 · Cited by 1

[Three-dimensional bioprinted microstructure promotes proliferation and viability of murine epithelial stem cells in vitro].

Liu, Y.-F., Huang, S., Yao, B., Zhao, L., Li, X., Fu, X., & Xu, W. (2017) · Europe PMC (PubMed Central) · doi:10.3969/j.issn.1673-4254.2017.06.08

Genetic and Environmental Factors that Control Merkel Cell Development and Survival

Logan-Graf, G. (2017) · D-Scholarship@Pitt (University of Pittsburgh)

Environmental Influences on the Development of Epidermal Progenitors

Kogut, I., & Bilousova, G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65469-7

Spatially restricted long‐term transgene expression in the developing skin used for studying the interaction of epidermal development and sensory innervation

Chan, C. C. M., Kamiguchi, H., & Shimogori, T. (2019) · Development Growth & Differentiation · doi:10.1111/dgd.12603

The delta opioid receptor influences circadian rhythms in human N/TERT-1 keratinocytes through the ?-arrestin pathway

Junnarkar, S. (2019) · doi:10.32657/10220/49501

An Engrailed1 enhancer underlies human thermoregulatory evolutionPreprint

Aldea, D., Atsuta, Y., Kokalari, B., Schaffner, S. F., Warder, B. N., & Kamberov, Y. G. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.22.262659

Embryology of the Skin

Ellenbogen, E. (2021) · Springer eBooks · doi:10.1007/978-3-030-54779-0_1

A new clustering algorithm for genes with multiple cancer diseases by self-consistent field iteration method

Liu, Y., & Ng, M. K. (2022) · Network Modeling Analysis in Health Informatics and Bioinformatics · doi:10.1007/s13721-022-00362-6

IN VIVO ACTIVATION OF P2Y4 PURINERGIC RECEPTORS USING ATP IN RAT EPIDERMAL TISSUE

Dosh, R. H., Khalfa, H. M., Al-Rehemi, S. M., AL-Msaid, H. L. F., & Hadi, N. (2022) · Wiadomości Lekarskie · doi:10.36740/wlek202211203

Signals from Beneath, and Stem Cells

Liu, S., Zhang, H., & 段, 恩. (2013)

Epidermal Stem Cells and Their Epigenetic Regulation

Shen, Q., Jin, H., & Wang, X. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140917861 · Cited by 21

Review Epidermal Stem Cells and Their Epigenetic Regulation

Shen, Q., Jin, H., & Wang, X. (2013)

Stem cells in embryonic skin development

Forni, M. F., Trombetta-Lima, M., & Sogayar, M. C. (2012) · Biological Research · doi:10.4067/s0716-97602012000300003 · Cited by 46

Stem cells in ectodermal development

Benitah, S. A., & Frye, M. (2012) · Journal of Molecular Medicine · doi:10.1007/s00109-012-0908-x · Cited by 37