The DOI matches its Crossref record; 247 of the 247 references it cites were found in a registry or an index.
Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization
Open accessAbstract
During the last few decades, improvements in the planning and application of radiotherapy in combination with surgery and chemotherapy resulted in increased survival rates of tumor patients. However, the success of radiotherapy is impaired by two reasons: firstly, the radioresistance of tumor cells and, secondly, the radiation-induced damage of normal tissue cells located in the field of ionizing radiation. These limitations demand the development of drugs for either radiosensitization of tumor cells or radioprotection of normal tissue cells. In order to identify potential targets, a detailed understanding of the cellular pathways involved in radiation response is an absolute requirement. This review describes the most important pathways of radioresponse and several key target proteins for radiosensitization.
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The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance
Park, S.-Y., Lee, C.-J., Choi, J.-H., Kim, J.-H., Kim, J.-W., Kim, J.-Y., & Nam, J.-S. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1405-7 · Cited by 292
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Extracellular Vesicles in Modifying the Effects of Ionizing Radiation
Szatmári, T., Hargitai, R., Sáfrány, G., & Lumniczky, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225527 · Cited by 52
Metadata
- Authors
- Maier, P., Hartmann, L., Wenz, F., & Herskind, C.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2016-01-14
- Volume
- 17
- Issue
- 1
- Pages
- 102
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2238041893
- Cited by
- 414
- References
- 247
- FWCI
- 30.49
- Type
- journal article
- Language
- en
- Open access
- gold
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- Maier, P., Hartmann, L., Wenz, F., & Herskind, C. (2016). Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms17010102
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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