The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Emerging Roles of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Immunological Disorders and Cancer
Open accessAbstract
Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells. Recent evidence suggests that VCAM-1 is closely associated with the progression of various immunological disorders, including rheumatoid arthritis, asthma, transplant rejection, and cancer. This review covers the role and relevance of VCAM-1 in inflammation, and also highlights the emerging potential of VCAM-1 as a novel therapeutic target in immunological disorders and cancer.
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Detection of differentially abundant cell subpopulations in scRNA-seq data
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Metadata
- Authors
- Kong, D.-H., Kim, Y., Kim, M., Jang, J., & Lee, S.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2018-04-02
- Volume
- 19
- Issue
- 4
- Pages
- 1057
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2794944537
- Cited by
- 683
- References
- 9
- FWCI
- 29.75
- Type
- journal article
- Language
- en
- Open access
- gold
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- Kong, D.-H., Kim, Y., Kim, M., Jang, J., & Lee, S. (2018). Emerging Roles of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Immunological Disorders and Cancer. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms19041057
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