The DOI matches its Crossref record; 167 of the 167 references it cites were found in a registry or an index.
Resveratrol and Its Effects on the Vascular System
Open accessAbstract
Resveratrol, the phenolic substance isolated initially from Veratrum grandiflorum and richly present in grapes, wine, peanuts, soy, and berries, has been attracting attention of scientists and medical doctors for many decades. Herein, we review its effects on the vascular system. Studies utilizing cell cultures and pre-clinical models showed that resveratrol alleviates oxidative stress and inflammation. Furthermore, resveratrol suppresses vascular smooth muscle cell proliferation, promotes autophagy, and has been investigated in the context of vascular senescence. Pre-clinical models unambiguously demonstrated numerous vasculoprotective effects of resveratrol. In clinical trials, resveratrol moderately diminished systolic blood pressure in hypertensive patients, as well as blood glucose in patients with diabetes mellitus. Yet, open questions remain, as exemplified by a recent report which states that the intake of resveratrol might blunt certain positive effects of exercise in older persons, and further research addressing the framework for long-term use of resveratrol as a food supplement, will stay in demand.
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Endothelial Dysfunction: Is There a Hyperglycemia-Induced Imbalance of NOX and NOS?
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The role of tumor-associated macrophages in osteosarcoma progression – therapeutic implications
Huang, Q., Liang, X., Ren, T., Huang, Y., Zhang, H., Yu, Y., Chen, C., Wang, W., Niu, J., Lou, J., et al. (2021) · Cellular Oncology · doi:10.1007/s13402-021-00598-w · Cited by 118
Tkaczenko, H., & Kurhaluk, N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031098 · Cited by 80
Metadata
- Authors
- Breuss, J. M., Atanasov, A. G., & Uhrin, P.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2019-03-27
- Volume
- 20
- Issue
- 7
- Pages
- 1523
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2923094111
- Cited by
- 328
- References
- 167
- FWCI
- 15.09
- Type
- journal article
- Language
- en
- Open access
- gold
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