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Cited by 870

The DOI matches its Crossref record; 116 of the 116 references it cites were found in a registry or an index.

Mechanisms and Functions of Long Non-Coding RNAs at Multiple Regulatory Levels

Open access
Zhang, Xiaopei, Wang, Wei, Zhu, Weidong, Dong, Jie, Cheng, Yingying, Yin, Zujun, Shen, Fafu·2019·International Journal of Molecular Sciences

Abstract

Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression at the epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels in a variety of ways. They play important roles in biological processes such as chromatin remodeling, transcriptional activation, transcriptional interference, RNA processing, and mRNA translation. lncRNAs have important functions in plant growth and development; biotic and abiotic stress responses; and in regulation of cell differentiation, the cell cycle, and the occurrence of many diseases in humans and animals. In this review, we summarize the functions and mechanisms of lncRNAs in plants, humans, and animals at different regulatory levels.

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Metadata

Authors
Zhang, X., Wang, W., Zhu, W., Dong, J., Cheng, Y., Yin, Z., & Shen, F.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2019-11-08
Volume
20
Issue
22
Pages
5573
ISSN
1422-0067 (ISSN-L)
OpenAlex
W2982711111
Cited by
870
References
116
FWCI
23.43
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Mechanisms and Functions of Long Non-Coding RNAs at Multiple Regulatory Levels. https://app.cochat.ai/papers/10.3390/ijms20225573
The paper
Zhang, X., Wang, W., Zhu, W., Dong, J., Cheng, Y., Yin, Z., & Shen, F. (2019). Mechanisms and Functions of Long Non-Coding RNAs at Multiple Regulatory Levels. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms20225573

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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