The DOI matches its Crossref record; 170 of the 170 references it cites were found in a registry or an index.
Current Knowledge and Future Perspectives on Mesenchymal Stem Cell-Derived Exosomes as a New Therapeutic Agent
Open accessAbstract
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and strong immunomodulatory activity. Recent studies indicate that the pleiotropic effects of MSCs, especially their immunomodulatory potential, can be largely attributed to paracrine factors. Exosomes, vesicles that are 30-150 nanometers in diameter that function in cell-cell communication, are one of the key paracrine effectors. MSC-derived exosomes are enriched with therapeutic miRNAs, mRNAs, cytokines, lipids, and growth factors. Emerging evidences support the compelling possibility of using MSC-derived exosomes as a new form of therapy for treating several different kinds of disease such as heart, kidney, immune diseases, neural injuries, and neurodegenerative disease. This review provides a summary of current knowledge and discusses engineering of MSC-derived exosomes for their use in translational medicine.
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Cites
3 retracted
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Cited by
Cao, J.-Y., Wang, B., Tang, T.-T., Wen, Y., Li, Z.-L., Feng, S.-T., Wu, M., Liu, D., Yin, D., Ma, K.-L., et al. (2021) · Theranostics · doi:10.7150/thno.54550 · Cited by 303
Exosome-Based Drug Delivery: Translation from Bench to Clinic
Koh, H. B., Kim, H. J., Kang, S.-W., & Yoo, T.-H. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15082042 · Cited by 259
Ma, Z.-J., Yang, J.-J., Lu, Y.-B., Liu, Z.-Y., & Wang, X.-X. (2020) · World Journal of Stem Cells · doi:10.4252/wjsc.v12.i8.814 · Cited by 155
Moeinabadi-Bidgoli, K., Babajani, A., Yazdanpanah, G., Farhadihosseinabadi, B., Jamshidi, E., Bahrami, S., & Niknejad, H. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112026 · Cited by 70
Exosomes and Biomaterials: In Search of a New Therapeutic Strategy for Multiple Sclerosis
Ojeda-Hernández, D. D., Hernández-Sapiéns, M. A., Reza-Zaldívar, E. E., Canales-Aguirre, A., Matías-Guiu, J. A., Matías-Guiu, J., Mateos-Díaz, J. C., Gómez-Pinedo, U., & Sancho-Bielsa, F. (2022) · Life · doi:10.3390/life12091417 · Cited by 25
Metadata
- Authors
- Joo, H. S., Suh, J. H., Lee, H. J., Bang, E. S., & Lee, J. M.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-01-22
- Volume
- 21
- Issue
- 3
- Pages
- 727
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3002731232
- Cited by
- 284
- References
- 170
- FWCI
- 13.35
- Type
- journal article
- Language
- en
- Open access
- gold
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- Joo, H. S., Suh, J. H., Lee, H. J., Bang, E. S., & Lee, J. M. (2020). Current Knowledge and Future Perspectives on Mesenchymal Stem Cell-Derived Exosomes as a New Therapeutic Agent. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21030727
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
