The DOI matches its Crossref record; 198 of the 199 references it cites were found in a registry or an index.
Fibromyalgia: Recent Advances in Diagnosis, Classification, Pharmacotherapy and Alternative Remedies
Open accessAbstract
Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic disease. FM is a condition which has been associated with diseases such as infections, diabetes, psychiatric or neurological disorders, rheumatic pathologies, and is a disorder that rather than diagnosis of exclusion requires positive diagnosis. A multidimensional approach is required for the management of FM, including pain management, pharmacological therapies, behavioral therapy, patient education, and exercise. The purpose of this review is to summarize the recent advances in classification criteria and diagnostic criteria for FM as well as to explore pharmacotherapy and the use of alternative therapies including the use of plant bioactive molecules.
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“Fourth, it is compliant with the generally poor efficacies of drugs currently used in FM therapy, but also with the relatively higher efficacy of gabapentinoids [7,140].”
From Fibromyalgia pathogenesis explained by a neuroendocrine multistable model (2024) · cites this paper as [7]
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1 retracted
Janzen, T. B., Paneduro, D., Picard, L. M., GORDON, A. S., & Bartel, L. (2019) · PLoS ONE · doi:10.1371/journal.pone.0212021 · Cited by 12
RetractedThe american college of rheumatology 1990 criteria for the classification of fibromyalgia
Wolfe, F., Smythe, H. A., Yunus, M. B., Bennett, R. M., Bombardier, C., Goldenberg, D. L., Tugwell, P., Campbell, S. M., Abeles, M., Clark, P., et al. (1990) · Arthritis & Rheumatism · doi:10.1002/art.1780330203 · Cited by 9,563
Molecular characterization of a peripheral receptor for cannabinoids
Munro, S., Thomas, K. L., & Abu-Shaar, M. (1993) · Nature · doi:10.1038/365061a0 · Cited by 5,092
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572
Treede, R.-D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., et al. (2019) · Pain · doi:10.1097/j.pain.0000000000001384 · Cited by 3,478
2016 revisions to the 2010/2011 fibromyalgia diagnostic criteria
Wolfe, F., Clauw, D. J., Fitzcharles, M.-A., Goldenberg, D. L., Häuser, W., Katz, R. L., Mease, P. J., Russell, A. S., Russell, I. J., & Walitt, B. (2016) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2016.08.012 · Cited by 2,232
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
Pacher, P., Bátkai, S., & Kunos, G. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.2 · Cited by 2,077
Gut/brain axis and the microbiota
Mayer, E. A., Tillisch, K., & Gupta, A. (2015) · Journal of Clinical Investigation · doi:10.1172/jci76304 · Cited by 1,503
WOLFE, F., CLAUW, D. J., FITZCHARLES, M.-A., GOLDENBERG, D. L., HÄUSER, W., KATZ, R. S., MEASE, P., RUSSELL, A. S., RUSSELL, I. J., & WINFIELD, J. B. (2011) · The Journal of Rheumatology · doi:10.3899/jrheum.100594 · Cited by 1,499
Beta-caryophyllene is a dietary cannabinoid.
Gertsch, J., Leonti, M., Raduner, S., Racz, I., Chen, J.-Z., Xie, X.-Q., Altmann, K.-H., Karsak, M., & Zimmer, A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803601105 · Cited by 906
Research works printed but not linked: 2
- Gur, 2006, Low dose of tramadol in the treatment of fibromyalgia syndrome: A controlled clinical trial versus placebo, Ann. Rheum. Dis., 65, 556
- Borchardt, 1996, Myrrh: An analgesic with a 4000-year history, Drug News Perspect., 9, 554
Cited by
Sorted by citations
Maffei, M. E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010181 · Cited by 236
Self-citationJurado-Priego, L. N., Cueto‐Ureña, C., Ramírez-Expósito, M. J., & Martínez-Martos, J. M. (2024) · Biomedicines · doi:10.3390/biomedicines12071543 · Cited by 152
Oxidative Stress in Fibromyalgia: From Pathology to Treatment
Assavarittirong, C., Samborski, W., & Grygiel‐Górniak, B. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/1582432 · Cited by 99
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from?
Toogood, P. L., Clauw, D. J., Phadke, S., & Hoffman, D. L. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105465 · Cited by 68
Zeng, L., Yang, K., He, Q., Zhu, X., Long, Z., Wu, Y., Chen, J., Li, Y., Zeng, J., Cui, G., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03303-4 · Cited by 72
Metadata
- Authors
- Maffei, M. E.
- Affiliations
- University of Turin (IT)
- Corresponding author
- Maffei, Massimo E.
- ORCID
- Maffei, Massimo E.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-10-23
- Volume
- 21
- Issue
- 21
- Pages
- 7877
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC7660651
- OpenAlex
- W3094598346
- Cited by
- 150
- References
- 199
- Citations by year
- 2026: 16 · 2025: 27 · 2024: 30 · 2023: 33 · 2022: 32 · 2021: 11 · 2020: 1
- FWCI
- 3.19
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
- Keywords
- fibromyalgia, diagnostic criteria, classification criteria, pharmacotherapy, complementary and alternative medicine, pain management, behavior therapy, physical activity, comorbidities
- MeSH terms
- Complementary Therapies, Behavior Therapy, Combined Modality Therapy, Exercise Therapy, Fibromyalgia, Humans, Patient Education as Topic, Pain Management, Phytochemicals
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