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Fibromyalgia: Recent Advances in Diagnosis, Classification, Pharmacotherapy and Alternative Remedies
Open accessAbstract
Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic disease. FM is a condition which has been associated with diseases such as infections, diabetes, psychiatric or neurological disorders, rheumatic pathologies, and is a disorder that rather than diagnosis of exclusion requires positive diagnosis. A multidimensional approach is required for the management of FM, including pain management, pharmacological therapies, behavioral therapy, patient education, and exercise. The purpose of this review is to summarize the recent advances in classification criteria and diagnostic criteria for FM as well as to explore pharmacotherapy and the use of alternative therapies including the use of plant bioactive molecules.
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“Fourth, it is compliant with the generally poor efficacies of drugs currently used in FM therapy, but also with the relatively higher efficacy of gabapentinoids [7,140].”
From Fibromyalgia pathogenesis explained by a neuroendocrine multistable model (2024) · cites this paper as [7]
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Metadata
- Authors
- Maffei, M. E.
- Affiliations
- University of Turin (IT)
- Corresponding author
- Maffei, Massimo E.
- ORCID
- Maffei, Massimo E.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2020-10-23
- Volume
- 21
- Issue
- 21
- Pages
- 7877
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC7660651
- OpenAlex
- W3094598346
- Cited by
- 150
- References
- 199
- Citations by year
- 2026: 16 · 2025: 27 · 2024: 30 · 2023: 33 · 2022: 32 · 2021: 11 · 2020: 1
- FWCI
- 3.19
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
- Keywords
- fibromyalgia, diagnostic criteria, classification criteria, pharmacotherapy, complementary and alternative medicine, pain management, behavior therapy, physical activity, comorbidities
- MeSH terms
- Complementary Therapies, Behavior Therapy, Combined Modality Therapy, Exercise Therapy, Fibromyalgia, Humans, Patient Education as Topic, Pain Management, Phytochemicals
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