The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Smart Hydrogels for Advanced Drug Delivery Systems
Open accessAbstract
Since the last few decades, the development of smart hydrogels, which can respond to stimuli and adapt their responses based on external cues from their environments, has become a thriving research frontier in the biomedical engineering field. Nowadays, drug delivery systems have received great attention and smart hydrogels can be potentially used in these systems due to their high stability, physicochemical properties, and biocompatibility. Smart hydrogels can change their hydrophilicity, swelling ability, physical properties, and molecules permeability, influenced by external stimuli such as pH, temperature, electrical and magnetic fields, light, and the biomolecules’ concentration, thus resulting in the controlled release of the loaded drugs. Herein, this review encompasses the latest investigations in the field of stimuli-responsive drug-loaded hydrogels and our contribution to this matter.
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Cites
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Translational Applications of Hydrogels
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Nanocomposite Hydrogels: 3D Polymer–Nanoparticle Synergies for On-Demand Drug Delivery
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Design and Applications of Photoresponsive Hydrogels
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Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques
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Emerging Role of Hydrogels in Drug Delivery Systems, Tissue Engineering and Wound Management
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Cited by
Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems
Delgado-Pujol, E. J., Martínez, G., Casado-Jurado, D., Vázquez, J., León-Barberena, J., Rodríguez-Lucena, D., Torres, Y., Alcudia, A., & Begines, B. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17020215 · Cited by 216
Novel strategies to reverse chemoresistance in colorectal cancer
Ma, S., Zhang, J., Yan, T., Miao, M., Cao, Y., Cao, Y., Zhang, L., & Li, L. (2023) · Cancer Medicine · doi:10.1002/cam4.5594 · Cited by 108
Hydrogel network architecture design space: impact on mechanical and viscoelastic properties
Roca-Arroyo, A. F., Gutierrez-Rivera, J. A., Morton, L. D., & Castilla-Casadiego, D. A. (2025) · Gels · doi:10.3390/gels11080588 · Cited by 88
Tharakan, S., Raja, I., Pietraru, A., Sarecha, E., Gresita, A., Petcu, E., Ilyas, A., & Hadjiargyrou, M. (2023) · Gels · doi:10.3390/gels9040274 · Cited by 18
Yadav, P., Warkar, S. G., & Kumar, A. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.146662 · Cited by 13
Metadata
- Authors
- Bordbar-Khiabani, A., & Gasik, M.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2022-03-27
- Volume
- 23
- Issue
- 7
- Pages
- 3665
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W4220940704
- Cited by
- 382
- References
- 88
- FWCI
- 21.10
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
