The DOI matches its Crossref record; 288 of the 288 references it cites were found in a registry or an index.
Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis
Open accessAbstract
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea. Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways, and nuclear transcription factors, EGCG possesses a wide variety of anti-inflammatory, antioxidant, antifibrotic, anti-remodelation, and tissue-protective properties which may be useful in the treatment of various diseases, particularly in cancer, and neurological, cardiovascular, respiratory, and metabolic disorders. This article reviews current information on the biological effects of EGCG in the above-mentioned disorders in relation to molecular pathways controlling inflammation, oxidative stress, and cell apoptosis.
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Citations
Cites
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“(ECG) in relation to some of their antioxidant actions [51,52,54,55].”
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Cited by
Ashraf, M. V., Khan, S., Misri, S., Gaira, K. S., Rawat, S., Rawat, B., Khan, M. A. H., Shah, A. A., Asgher, M., & Ahmad, S. (2024) · Pharmaceuticals · doi:10.3390/ph17080975 · Cited by 102
Dutta, S., Sengupta, P., Rao, S., Elgarawany, G. E., Samrot, A. V., Rosas, I. M., & Roychoudhury, S. (2025) · Pharmaceuticals · doi:10.3390/ph18101575 · Cited by 20
Cavanah, A. M., Robinson, L. A., Mattingly, M. L., & Frugé, A. D. (2025) · Biomedicines · doi:10.3390/biomedicines13071656 · Cited by 7
“EGCG has been found to bind to cell surface receptors like 67-kDa laminin receptor (anti-tumor) and toll-like receptor (anti-inflammatory) [14], with other published studies reporting it has antioxidant, anticancer, antidiabetic, antimicrobial, and neuroprotective roles [15].”
Metadata
- Authors
- Mokra, D., Joskova, M., & Mokry, J.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2022-12-25
- Volume
- 24
- Issue
- 1
- Pages
- 340
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W4313259898
- Cited by
- 355
- References
- 288
- FWCI
- 32.55
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis. https://app.cochat.ai/papers/10.3390/ijms24010340
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- Mokra, D., Joskova, M., & Mokry, J. (2022). Therapeutic Effects of Green Tea Polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in Relation to Molecular Pathways Controlling Inflammation, Oxidative Stress, and Apoptosis. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms24010340
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
