The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Smart Hydrogels in Tissue Engineering and Regenerative Medicine
Open accessAbstract
The field of regenerative medicine has tremendous potential for improved treatment outcomes and has been stimulated by advances made in bioengineering over the last few decades. The strategies of engineering tissues and assembling functional constructs that are capable of restoring, retaining, and revitalizing lost tissues and organs have impacted the whole spectrum of medicine and health care. Techniques to combine biomimetic materials, cells, and bioactive molecules play a decisive role in promoting the regeneration of damaged tissues or as therapeutic systems. Hydrogels have been used as one of the most common tissue engineering scaffolds over the past two decades due to their ability to maintain a distinct 3D structure, to provide mechanical support for the cells in the engineered tissues, and to simulate the native extracellular matrix. The high water content of hydrogels can provide an ideal environment for cell survival, and structure which mimics the native tissues. Hydrogel systems have been serving as a supportive matrix for cell immobilization and growth factor delivery. This review outlines a brief description of the properties, structure, synthesis and fabrication methods, applications, and future perspectives of smart hydrogels in tissue engineering.
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Cites
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Cited by
Alginate hydrogel dressings for advanced wound management
Zhang, M., & Zhao, X. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.07.311 · Cited by 616
Natural and Synthetic Polymers for Biomedical and Environmental Applications
Satchanska, G., Davidova, S., & Petrov, P. D. (2024) · Polymers · doi:10.3390/polym16081159 · Cited by 585
El-Husseiny, H. M., Mady, E. A., Hamabe, L., Abugomaa, A., Shimada, K., Yoshida, T., Tanaka, T., Yokoi, A., Elbadawy, M., & Tanaka, R. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2021.100186 · Cited by 533
Alginate: From Food Industry to Biomedical Applications and Management of Metabolic Disorders
Gheorghita Puscaselu, R., Lobiuc, A., Dimian, M., & Covasa, M. (2020) · Polymers · doi:10.3390/polym12102417 · Cited by 470
Askari, M., Afzali Naniz, M., Kouhi, M., Saberi, A., Zolfagharian, A., & Bodaghi, M. (2021) · Biomaterials Science · doi:10.1039/d0bm00973c · Cited by 369
Metadata
- Authors
- Mantha, S., Pillai, S., Khayambashi, P., Upadhyay, A., Zhang, Y., Tao, O., Pham, H. M., & Tran, S. D.
- Venue
- Materials
- Publisher
- MDPI AG
- Published
- 2019-10-12
- Volume
- 12
- Issue
- 20
- Pages
- 3323
- ISSN
- 1996-1944 (ISSN-L)
- OpenAlex
- W2979675549
- Cited by
- 857
- References
- 9
- FWCI
- 22.37
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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