The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Antioxidant Activity of Hawaiian Marine Algae
Open accessAbstract
Marine algae are known to contain a wide variety of bioactive compounds, many of which have commercial applications in pharmaceutical, medical, cosmetic, nutraceutical, food and agricultural industries. Natural antioxidants, found in many algae, are important bioactive compounds that play an important role against various diseases and ageing processes through protection of cells from oxidative damage. In this respect, relatively little is known about the bioactivity of Hawaiian algae that could be a potential natural source of such antioxidants. The total antioxidant activity of organic extracts of 37 algal samples, comprising of 30 species of Hawaiian algae from 27 different genera was determined. The activity was determined by employing the FRAP (Ferric Reducing Antioxidant Power) assays. Of the algae tested, the extract of Turbinaria ornata was found to be the most active. Bioassay-guided fractionation of this extract led to the isolation of a variety of different carotenoids as the active principles. The major bioactive antioxidant compound was identified as the carotenoid fucoxanthin. These results show, for the first time, that numerous Hawaiian algae exhibit significant antioxidant activity, a property that could lead to their application in one of many useful healthcare or related products as well as in chemoprevention of a variety of diseases including cancer.
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“However, when attempting to reproduce their synthesis artificially, a decrease in activity with respect to those obtained directly from natural matrices was observed [162].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [162]
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Metadata
- Authors
- Kelman, D., Posner, E. K., McDermid, K. J., Tabandera, N. K., Wright, P. R., & Wright, A. D.
- Affiliations
- University of Hawaii at Hilo (US)
- University of Freiburg (DE)
- Corresponding author
- Wright, Anthony D.
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2012-02-15
- Volume
- 10
- Issue
- 2
- Pages
- 403-416
- ISSN
- 1660-3397 (ISSN-L)
- PMC
- PMC3297004
- OpenAlex
- W2079779859
- Cited by
- 250
- References
- 43
- Citations by year
- 2026: 8 · 2025: 13 · 2024: 12 · 2023: 22 · 2022: 30 · 2021: 24 · 2020: 30 · 2019: 23 · 2018: 21 · 2017: 13 · 2016: 9 · 2015: 13 · 2014: 12 · 2013: 16 · 2012: 4
- FWCI
- 21.08
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Marine Drugs (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
- Keywords
- antioxidant activity, marine algae, Turbinaria ornata, fucoxanthin, carotenoids, bioassay-guided fractionation, oxidative damage, chemoprevention, natural antioxidants
- MeSH terms
- Phaeophyceae, Chlorophyta, Rhodophyta, Antioxidants, Hawaii, Pacific Ocean, Species Specificity, Xanthophylls, Drug Discovery
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