Cited by 250Seaweed-derived Bioactive CompoundsPhytochemicals and Antioxidant ActivitiesMarine and coastal plant biology

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Antioxidant Activity of Hawaiian Marine Algae

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Kelman, Dovi, Posner, Ellen Kromkowski, McDermid, Karla J., Tabandera, Nicole K., Wright, Patrick R., Wright, Anthony D.·2012·Marine Drugs

DOI 10.3390/md10020403PMC PMC3297004

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Abstract

Marine algae are known to contain a wide variety of bioactive compounds, many of which have commercial applications in pharmaceutical, medical, cosmetic, nutraceutical, food and agricultural industries. Natural antioxidants, found in many algae, are important bioactive compounds that play an important role against various diseases and ageing processes through protection of cells from oxidative damage. In this respect, relatively little is known about the bioactivity of Hawaiian algae that could be a potential natural source of such antioxidants. The total antioxidant activity of organic extracts of 37 algal samples, comprising of 30 species of Hawaiian algae from 27 different genera was determined. The activity was determined by employing the FRAP (Ferric Reducing Antioxidant Power) assays. Of the algae tested, the extract of Turbinaria ornata was found to be the most active. Bioassay-guided fractionation of this extract led to the isolation of a variety of different carotenoids as the active principles. The major bioactive antioxidant compound was identified as the carotenoid fucoxanthin. These results show, for the first time, that numerous Hawaiian algae exhibit significant antioxidant activity, a property that could lead to their application in one of many useful healthcare or related products as well as in chemoprevention of a variety of diseases including cancer.

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Figure 1 Total antioxidant activity of organic extracts of Hawaiian algae presented as mean FRAP values in μM per μg extract. Error bars ± SD. The different colors represent the different algal groups. In cases where there are more than one sample of the same species collected at a different date or location (see Table 1), the date and/or location code was added. Hilo for Richardson’s Ocean Park; Ninole,for Punaluu Beach Park; Four-mile for Four-mile Beach Park; King’s, for King’s Landing.CC BY · PubMed Central

Figure 2 Bioassay-guided fractionation of Turbinaria ornata and the isolation of fucoxanthin as the active antioxidant: (a) Preperative HPLC chromatogram of T. ornata methanol extract; relative absorbance at 254 nm is presented. The peak that correlates to fraction 18 is indicated; (b) Total antioxidant activity of fractions collected from the preperative HPLC of T. ornata extract, presented as mean FRAP value in µM. Error bars ± SD; (c) The UV-visible absorbance spectrum corresponding to the HPLC peak of purified fraction 18. λmax at 264 and 449 nm are indicated; and, (d) Chemical structure of fucoxanthin, the major antioxidant component of T. ornata extract.CC BY · PubMed Central

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Park, E.-J., & Pezzuto, J. M. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5235 · Cited by 49
The use of marine-derived bioactive compounds as potential hepatoprotective agents
Nair, D. G., Weiskirchen, R., & Al-Musharafi, S. K. (2014) · Acta Pharmacologica Sinica · doi:10.1038/aps.2014.114 · Cited by 51
Antioxidant, anti-inflammatory and anticancer potential of natural bioactive compounds from seaweeds
Ravi, S., & Devi, K. P. (2019) · Studies in natural products chemistry · doi:10.1016/b978-0-12-817901-7.00005-8 · Cited by 48
In vitro cytotoxicity and pro-apoptotic activity of phycocyanin nanoparticles from Ulva lactuca (Chlorophyta) algae
Al‐Malki, A. L. (2020) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2019.12.037 · Cited by 48
“Percentage of cell growth inhibition following exposure to ULNAP was calculated as mentioned (Kelman et al., 2012; Rosaline et al., 2012).”
Method
Anti-Cancer Mechanism and Possibility of Nano-Suspension Formulation for a Marine Algae Product Fucoxanthin
Srinivasan, M., & Francis, S. P. (2013) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2013.14.4.2213 · Cited by 50
“damage (Kelman et al., 2012).”
A review on marine-based phytochemicals and their application in biomedical research
Khatun, R., Singh, S., Dubey, N. K., & Das, A. P. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-19143-5.00013-x · Cited by 45
Pro-Apoptotic Activity of French Polynesian Padina pavonica Extract on Human Osteosarcoma Cells
Bernardini, G., Minetti, M., Polizzotto, G., Biazzo, M., & Santucci, A. (2018) · Marine Drugs · doi:10.3390/md16120504 · Cited by 45
“They have been reported to possess several biological activities including anti-oxidant, anti-bacterial and anti-allergic and anti-diabetes, and to be involved in the protection against several human diseases such as cancer, coronary heart disease, inflammatory and neurodegenerative diseases and aging [14,15].”
Background
Exploring Ulva australis Areschoug for possible biotechnological applications: In vitro antioxidant and enzymatic inhibitory properties, and fatty acids contents
Trentin, R., Custódio, L. M. B., Rodrigues, M. J., Moschin, E., Sciuto, K., Silva, J. P. D., & Moro, I. (2020) · Algal Research · doi:10.1016/j.algal.2020.101980 · Cited by 45
A Review of Marine Algae as a Sustainable Source of Antiviral and Anticancer Compounds
Kumar, A., Soratur, A., Kumar, S., & Maran, B. A. V. (2025) · Macromol—A Journal of Macromolecular Research · doi:10.3390/macromol5010011 · Cited by 43
“Additionally, research on Hawaiian algae revealed that the extract of Turbinaria ornata exhibited the highest antioxidant activity, with fucoxanthin identified as the primary bioactive antioxidant compound [43,46,47].”
Antioxidant Activities of Various Brown Seaweeds from Seribu Islands
Diachanty, S., Nurjanah, N., & Abdullah, A. (2017) · Jurnal Pengolahan Hasil Perikanan Indonesia · doi:10.17844/jphpi.v20i2.18013 · Cited by 43
“…pada beberapa rumput laut seperti P. polysiphonia dan Turbinaria sp., dan memiliki peranan penting terhadap berbagai penyakit, proses penuaan dan memiliki potensi anti-aging, anti inflamasi, anti bakteri, anti jamur, sitotoksik, anti malaria, anti proliferasi serta anti kanker (Kelman et al. 2012).”
Background
Antioxidant properties of some filamentous green algae (Chaetomorpha Genus)
Farasat, M., Khavari-Nejad, R. A., Nabavi, S. M. B., & Namjooyan, F. (2013) · Brazilian Archives of Biology and Technology · doi:10.1590/s1516-89132013000600005 · Cited by 42
“Seaweeds are known to contain a wide variety of bioactive compounds, many of which have commercial applications in the pharmaceutical, medical, cosmetic, food industries and agriculture (Kelman et al. 2012).”
Background
An overview of odoriferous marine seaweeds of the Dictyopteris genus: insights into their chemical diversity, biological potential and ecological roles
Zatelli, G. A., Philippus, A. C., & Falkenberg, M. B. (2018) · Revista Brasileira de Farmacognosia · doi:10.1016/j.bjp.2018.01.005 · Cited by 43
Phomopsichin A–D; Four New Chromone Derivatives from Mangrove Endophytic Fungus Phomopsis sp. 33#
Huang, M., Li, J., Liu, L., Yin, S., Wang, J., & Lin, Y. (2016) · Marine Drugs · doi:10.3390/md14110215 · Cited by 40
“Radical scavenging effect on OH of compounds 1–5 were carried out according to previously reported methods [29,30].”
Method
Phytochemical profiling of Turbinaria ornata and its antioxidant and anti-proliferative effects
Deepak, P., Sowmiya, R., Balasubramani, G., & Perumal, P. (2017) · Journal of Taibah University Medical Sciences · doi:10.1016/j.jtumed.2017.02.002 · Cited by 40
“A wide range of biological properties of this seaweed, including antibacterial,(12) anti-coagulant,(13) anti-inflammatory(14) and antioxidant properties, have been reported.(15) In addition, studies on fucoidan isolated from Turbinaria spp.”
Background
Facile production of seaweed-based biomaterials with antioxidant and anti-inflammatory activities
Guzmán‐Puyol, S., Russo, D., Penna, I., Ceseracciu, L., Palazón, F., Scarpellini, A., Cingolani, R., Bertorelli, R., Bayer, I. S., Heredia‐Guerrero, J. A., et al. (2017) · Algal Research · doi:10.1016/j.algal.2017.08.015 · Cited by 39
Use of algae in strawberry management
Righini, H., Roberti, R., & Baraldi, E. (2018) · Journal of Applied Phycology · doi:10.1007/s10811-018-1478-2 · Cited by 39
“higher antioxidant activity shown by brown algae with respect to green and the red ones (Kelman et al. 2012).”
BackgroundResult
Phytochemical profiling of marine red alga, Halymenia palmata and its bio-control effects against Dengue Vector, Aedes aegypti
Deepak, P., Balasubramanian, B., Park, S., Sowmiya, R., Balasubramani, G., Aiswarya, D., Amutha, V., & Perumal, P. (2018) · South African Journal of Botany · doi:10.1016/j.sajb.2018.11.011 · Cited by 39
Antimicrobial and Antioxidant Potential of Scenedesmus obliquus Microalgae in the Context of Integral Biorefinery Concept
Zaharieva, M. M., Zheleva‐Dimitrova, D., Rusinova-Videva, S., Ilieva, Y. E., Brachkova, A., Balabanova, V., Gevrenova, R., Kim, T. C., Kaleva, M. D., Georgieva, A., et al. (2022) · Molecules · doi:10.3390/molecules27020519 · Cited by 39
Transcriptome analysis reveals mechanisms of geroprotective effects of fucoxanthin in Drosophila
Moskalev, A., Shaposhnikov, M. V., Zemskaya, N. V., Belyi, A., Dobrovolskaya, E., Patova, A., Guvatova, Z. G., Lukyanova, E., Snezhkina, A. V., & Kudryavtseva, A. V. (2018) · BMC Genomics · doi:10.1186/s12864-018-4471-x · Cited by 36
“Background Fucoxanthin is a one of the most abundant marine carotenoids, which is widely distributed in brown algae of the genera Alaria, Cladosiphon, Cystoseira, Eisenia, Fucus, Hijikia, Ishige, Kjellmaniella, Laminaria, Myagropsis, Padina, Petalonia, Sargassum, Turbinaria, Undaria and others [1, 2], as well as in di…”
Antioxidant Properties of two Edible Green Seaweeds From Northern Coasts of the Persian Gulf
Farasat, M., Khavari-Nejad, R. A., Nabavi, S. M. B., & Namjooyan, F. (2013) · Jundishapur Journal of Natural Pharmaceutical Products · doi:10.5812/jjnpp.7736 · Cited by 35
Seasonal Nutritional Profile of Gelidium corneum (Rhodophyta, Gelidiaceae) from the Center of Portugal
Cavaco, M., Duarte, A., Freitas, M. V., Afonso, C., Bernardino, S. M. S. A., Pereira, L., Martins, M., & Mouga, T. (2021) · Foods · doi:10.3390/foods10102394 · Cited by 36
“echinocarpum); green algae such as Gayralia oxysperma and Chaetomorpha antennina; and other red algae such as Wilsonosiphonia howei (formerly Polysiphonia howei), Gymnogongrus durvillei (formerly Ahnfeltiopsis concinna), and Pterocladiella capilacea [111].”
Background
Ochratoxin A and Kidney Oxidative Stress: The Role of Nutraceuticals in Veterinary Medicine—A Review
Longobardi, C., Ferrara, G., Andretta, E., Montagnaro, S., Damiano, S., & Ciarcia, R. (2022) · Toxins · doi:10.3390/toxins14060398 · Cited by 34
Seasonal Changes in the Biochemical Constituents of Green Seaweed Chaetomorpha antennina from Covelong, India
Vinuganesh, A., Kumar, A., Korany, S. M., Alsherif, E. A., Selim, S., Prakash, S., Beemster, G. T. S., & AbdElgawad, H. (2022) · Biomolecules · doi:10.3390/biom12101475 · Cited by 33
Characteristics of Green Seaweeds from Seribu Islands and Sekotong West Nusa Tenggara Antioxidant
Nufus, C., Nurjanah, N., & Abdullah, A. (2017) · Jurnal Pengolahan Hasil Perikanan Indonesia · doi:10.17844/jphpi.v20i3.19819 · Cited by 32
“…senyawa bioaktif yaitu fenol, saponin, tanin, flavonoid, sesquiterpenoid, diterpenoid dan caulerpin yang memiliki aktivitas antioksidan, anti bakteri, anti jamur, anti tumor dan bisa digunakan untuk terapi tekanan darah rendah serta penurun glukosa darah (Kelman et al. 2012; Azhagu et al. 2015).”
Background
Antioxidant activity of three seaweeds from tropical reefs of Brazil: potential sources for bioprospecting
Vasconcelos, J. B., de Vasconcelos, E. R. T. P. P., Urrea‐Victoria, V., Bezerra, P. S., Reis, T. N. V., Cocentino, A. D. L. M., Navarro, D. M. D. A. F., Chow, F., Areces, A. J., & FUJII, M. T. (2018) · Journal of Applied Phycology · doi:10.1007/s10811-018-1556-5 · Cited by 35
Manipulating antioxidant content in macroalgae in intensive land-based cultivation systems for functional food applications
Magnusson, M. E., Mata, L., Na, W., Zhao, J., de Nys, R., & Paul, N. A. (2015) · Algal Research · doi:10.1016/j.algal.2015.02.007 · Cited by 30
“Ferric reducing antioxidant power (FRAP) was determined following [19] with minor modifications in the use of Trolox as the standard (7 to 250 μM, R = 0.”
Method
Application of Two-Level Full Factorial Design for the Extraction of Fucoxanthin and Antioxidant Activities from Sargassum siliquosum and Sargassum polycystum
Lim, M. W. S., Tan, K. M., Chew, L. Y., Kong, K. W., & Yan, S. W. (2018) · Journal of Aquatic Food Product Technology · doi:10.1080/10498850.2018.1448918 · Cited by 29
“Another study, by Kelman et al. (2012), showed that antioxidant activity of Hawaiian brown algae assayed by FRAP was highest compared to red and green algae.”
Background
Harnessing microalgae as a bioresource for nutraceuticals: advancing bioactive compound exploration and shaping the future of health and functional food innovation
Ayub, A., Rahayu, F., Khamidah, A., Antarlina, S. S., Iswari, K., Supriyadi, K., Mufidah, E., Singh, A., Chopra, C., & Wani, A. K. (2025) · Discover Applied Sciences · doi:10.1007/s42452-025-06916-3 · Cited by 29
“E x t r a c t o r s u pp l e m e n t D N A r e p a i r a n d h i s t o n e m e t h y l a t i o n a s w e ll a s c h e m o - p r e v e n t i v e a c t i v i t i e s , N u t r a c e u t i c a l s , c o s m e t i c s [ 44 , 45 ]”
Seaweed resources of the Hawaiian Islands
McDermid, K. J., Martin, K. J., & Haws, M. C. (2019) · Botanica Marina · doi:10.1515/bot-2018-0091 · Cited by 28
Carotenoid biosynthesis is associated with low-temperature adaptation in Rhodosporidium kratochvilovae
Guo, R., Liu, T., Guo, C., Chen, G., Fan, J., & Zhang, Q. (2022) · BMC Microbiology · doi:10.1186/s12866-022-02728-2 · Cited by 28
Epiphytic marine pigmented bacteria: A prospective source of natural antioxidants
Pawar, R. T., Mohandass, C., Sivaperumal, E., Sabu, E. A., Rajasabapathy, R., & Jagtap, T. G. (2015) · Brazilian Journal of Microbiology · doi:10.1590/s1517-838246120130353 · Cited by 28
“High potent strains and their source Considering the source of the potent strains, the high- est antioxidant producing strain PIGB77 was found to be associated with Sargassum species (Phaeophyta) whereas the other two strains belonged to Chaetomorpha and Ulva spp. (Chlorophyta) (Table 5).”
BackgroundInfluential
Effects of Antioxidant, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase of The Extract and Fraction From Turbinaria decurrens Bory.
Nurrochmad, A., Wirasti, W., Dirman, A., Lukitaningsih, E., Rahmawati, A., & Fakhrudin, N. (2018) · INDONESIAN JOURNAL OF PHARMACY · doi:10.14499/indonesianjpharm29iss4pp188 · Cited by 30
“The major bioactive compound that responsible for antioxidant activity in macroalgae was identified as the carotenoid fucoxanthin (Kelman et al., 2012).”
Background
Antioxidant activity of Rhodophyceae extracts from Atlantic and Mediterranean Coasts of Morocco
Bouhlal, R. (2013) · African Journal of Plant Science · doi:10.5897/ajps12.048 · Cited by 26
“Seaweeds are considered to be a rich source of antioxidants (Cahyana et al., 1992; Devi et al., 2011; Kelman et al., 2012; Murugan and Iyer, 2012; Kim et al., 2012).”
Background
Algae and Cyanobacteria as Biocontrol Agents of Fungal Plant Pathogens
Righini, H., & Roberti, R. (2019) · Springer eBooks · doi:10.1007/978-3-030-19831-2_9 · Cited by 26
Total Phenolic Levels, In Vitro Antioxidant Properties, and Fatty Acid Profile of Two Microalgae, Tetraselmis marina Strain IMA043 and Naviculoid Diatom Strain IMA053, Isolated from the North Adriatic Sea
Trentin, R., Custódio, L. M. B., Rodrigues, M. J., Moschin, E., Sciuto, K., Silva, J. P. D., & Moro, I. (2022) · Marine Drugs · doi:10.3390/md20030207 · Cited by 26
“However, these differences can be explained by different causes, including interspecific variations and extrinsic factors, such as light intensity, salinity, and nutrient levels, or by the different tested extracts [45].”
Background
Algae from Portuguese Coast Presented High Cytotoxicity and Antiproliferative Effects on an In vitro Model of Human Colorectal Cancer.
Alves, C., Pintéus, S., Rodrigues, A. J., Horta, A., & Pedrosa, R. (2018) · PubMed Central · doi:10.4103/pr.pr_151_16 · Cited by 27
Surface Functionalization of Bioactive Glasses with Polyphenols from Padina pavonica Algae and In Situ Reduction of Silver Ions: Physico-Chemical Characterization and Biological Response
Abdelgeliel, A. S., Ferraris, S., Cochis, A., Vitalini, S., Iriti, M., Mohammed, H., Kumar, A., Cazzola, M., Salem, W., Verné, E., et al. (2019) · Coatings · doi:10.3390/coatings9060394 · Cited by 26
“Amongst them, Padina pavonica is a famous species of Egyptian marine algae that demonstrated antioxidant properties due to its polyphenols content [13,14].”
Background
Asparagopsis Genus: What We Really Know About Its Biological Activities and Chemical Composition
Ponte, J. M. S., Seca, A. M. L., & Barreto, M. D. C. (2022) · Molecules · doi:10.3390/molecules27061787 · Cited by 27
“Many algal extracts that have been tested over the years have also displayed pharmacological properties, such as antioxidant activity [19,20], anti-inflammatory activity [19], antimicrobial activity [21], antiviral activity [22], anticancer activity [23], antiprotozoal activity [24] neuroprotective activity [25], amon…”
Background
The potency of green algae Chaetomorpha crassa Agardh as antioxidant agent from the coastal of Lhok Bubon, West Aceh
Gazali, M., Zamani, N. P., & Nurjanah, N. (2019) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/278/1/012029 · Cited by 25
Antioxidative and antimicrobial activities of intertidal seaweeds and possible effects of abiotic factors on these bioactivities
Xu, P., Tan, H., Jin, W., Li, Y., Santhoshkumar, C., Li, P., & Liu, W. (2018) · Journal of Oceanology and Limnology · doi:10.1007/s00343-019-7046-z · Cited by 23
Defatted Microalgae-Mediated Enrichment of n–3 Polyunsaturated Fatty Acids in Chicken Muscle Is Not Affected by Dietary Selenium, Vitamin E, or Corn Oil
Tao, L., Sun, T., Magnuson, A. D., Qamar, T. R., & Lei, X. G. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy164 · Cited by 23
Characteristics of Turbinaria conoides and Padina Minor As Raw Materials For Healthy Seaweed Salt
Nurjanah, N., Abdullah, A., & Diachanty, S. (2020) · Pharmacognosy Journal · doi:10.5530/pj.2020.12.93 · Cited by 23
Nanoencapsulated Extract of a Red Seaweed (Rhodophyta) Species as a Promising Source of Natural Antioxidants
Maghraby, Y. R., Farag, M. A., Kontominas, M. G., Shakour, Z. T. A., & Ramadan, A. R. (2022) · ACS Omega · doi:10.1021/acsomega.1c05517 · Cited by 22
Variation of the Nutritional Composition and Bioactive Potential in Edible Macroalga Saccharina latissima Cultivated from Atlantic Canada Subjected to Different Growth and Processing Conditions
Lafeuille, B., Tamigneaux, É., Berger, K., Provencher, V., & Beaulieu, L. (2023) · Foods · doi:10.3390/foods12081736 · Cited by 22
“[58] and adapted from previously described methods [12,55].”
Method
Circular economy approaches for the production of high-value polysaccharides from microalgal biomass grown on industrial fish processing wastewater: A review
Rifna, E. J., Rajauria, G., Dwivedi, M., & Tiwari, B. K. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.126887 · Cited by 22
Antioxidant and anti cancer activities of brown and red seaweed extracts from Chilean coasts
Miranda, A., Montoya, M. L., Paz-Araos, M., Mellado, M., Villena, J., Arancibia, P., Madrid, A., & Jara‐Gutiérrez, C. (2018) · Latin American Journal of Aquatic Research · doi:10.3856/vol46-issue2-fulltext-6 · Cited by 22
“1 times higher) than those from Laurencia, Dictyota and Desmarestia reported elsewhere (Matarjun et al., 2008; Zubia et al., 2009a, 2009b; Kelman et al., 2012).”
MethodResultInfluential
Evaluation of the novel nanoparticle material – CdSe quantum dots on Chlorella pyrenoidosa and Scenedesmus obliquus: Concentration-time-dependent responses
Yan, K., Liu, Y., Yang, Q., Liu, W., Guo, R., Sui, J.-H., Yan, Z., & Chen, J. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.01.018 · Cited by 24
A comprehensive review of the brown macroalgal genus Turbinaria J.V. Lamouroux (Fucales, Sargassaceae)
Zubia, M., Stiger‐Pouvreau, V., Mattio, L., Payri, C. E., & Stewart, H. L. (2020) · Journal of Applied Phycology · doi:10.1007/s10811-020-02188-z · Cited by 23
“Turbinaria ornata from Hawaii exhibited the highest antioxidant activity among 30 species tested (Kelman et al. 2012) and the antioxidant compound was identified as the carotenoid fucoxanthin.”
Background
Bio-inspired drug delivery systems: A new attempt from bioinspiration to biomedical applications
Ming, L., Wu, H., Fan, Q., Dong, Z., Huang, J., Xiao, Z., Xiao, N., Huang, H., Liu, H., & Li, Z. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124221 · Cited by 21
Commercial Red Seaweed in Portugal (Gelidium sesquipedale and Pterocladiella capillacea, Florideophyceae): Going beyond a Single-Purpose Product Approach by Valorizing Bioactivity
Matos, J., Gomes‐Bispo, A., Cardoso, C. L., Afonso, C. M., Campos, A. M., Gomes, R., Fale, P. L. V., Delgado, I. M., Coelho, I., Castanheira, I. P., et al. (2019) · Thalassas An International Journal of Marine Sciences · doi:10.1007/s41208-019-00181-z · Cited by 20

Authors: Kelman, D., Posner, E. K., McDermid, K. J., Tabandera, N. K., Wright, P. R., & Wright, A. D.
Affiliations: University of Hawaii at Hilo (US)
University of Freiburg (DE)
Corresponding author: Wright, Anthony D.
ORCID: McDermid, Karla J.
Wright, Patrick R.
Venue: Marine Drugs
Publisher: MDPI AG
Published: 2012-02-15
Volume: 10
Issue: 2
Pages: 403-416
ISSN: 1660-3397 (ISSN-L)
DOI: 10.3390/md10020403
PMC: PMC3297004
OpenAlex: W2079779859
Cited by: 250
References: 43
Citations by year: 2026: 8 · 2025: 13 · 2024: 12 · 2023: 22 · 2022: 30 · 2021: 24 · 2020: 30 · 2019: 23 · 2018: 21 · 2017: 13 · 2016: 9 · 2015: 13 · 2014: 12 · 2013: 16 · 2012: 4
FWCI: 21.08
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (vor)
Locations: Marine Drugs (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
Keywords: antioxidant activity, marine algae, Turbinaria ornata, fucoxanthin, carotenoids, bioassay-guided fractionation, oxidative damage, chemoprevention, natural antioxidants
MeSH terms: Phaeophyceae, Chlorophyta, Rhodophyta, Antioxidants, Hawaii, Pacific Ocean, Species Specificity, Xanthophylls, Drug Discovery

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Antioxidant Activity of Hawaiian Marine Algae

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