The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012
Open accessAbstract
Every year, hundreds of new compounds are discovered from the metabolites of marine organisms. Finding new and useful compounds is one of the crucial drivers for this field of research. Here we describe the statistics of bioactive compounds discovered from marine organisms from 1985 to 2012. This work is based on our database, which contains information on more than 15,000 chemical substances including 4196 bioactive marine natural products. We performed a comprehensive statistical analysis to understand the characteristics of the novel bioactive compounds and detail temporal trends, chemical structures, species distribution, and research progress. We hope this meta-analysis will provide useful information for research into the bioactivity of marine natural products and drug development.
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Cites
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399
Natural products as sources of new drugs over the last 25 years
Newman, D. J., & Cragg, G. M. (2007) · Journal of Natural Products · doi:10.1021/np068054v · Cited by 5,517
Natural products as sources of new drugs over the 30 years from 1981 to 2010
Newman, D. J., & Cragg, G. M. (2012) · Journal of Natural Products · doi:10.1021/np200906s · Cited by 4,687
The influence of natural products upon drug discovery (Antiquity to late 1999)
Newman, D. J., Cragg, G. M., & Snader, K. M. (2000) · Natural Product Reports · doi:10.1039/a902202c · Cited by 1,293
Future directions for peptide therapeutics development
Kaspar, A. A., & Reichert, J. M. (2013) · Drug Discovery Today · doi:10.1016/j.drudis.2013.05.011 · Cited by 750
Marine natural products and their potential applications as anti-infective agents
Donia, M., & Hamann, M. T. (2003) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(03)00655-8 · Cited by 425
Immense essence of excellence: Marine microbial bioactive compounds
Bhatnagar, I., & Kim, S.-K. (2010) · Marine Drugs · doi:10.3390/md8102673 · Cited by 384
Highlights of marine natural products chemistry (1972–1999)
Faulkner, D. J. (2000) · Natural Product Reports · doi:10.1039/a909113k · Cited by 201
Cited by
Natural Products as a Source for Novel Antibiotics
Moloney, M. G. (2016) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2016.05.001 · Cited by 308
Labrenzbactin from a coral-associated bacterium Labrenzia sp
Raj Sharma, A., Zhou, T., Harunari, E., Oku, N., Trianto, A., & Igarashi, Y. (2019) · The Journal of Antibiotics · doi:10.1038/s41429-019-0192-x · Cited by 47
Metadata
- Authors
- Hu, Y., Chen, J., Hu, G., Yu, J., Zhu, X., Lin, Y., Chen, S., & Yuan, J.
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2015-01-07
- Volume
- 13
- Issue
- 1
- Pages
- 202-221
- ISSN
- 1660-3397 (ISSN-L)
- OpenAlex
- W2056014566
- Cited by
- 260
- References
- 8
- FWCI
- 15.65
- Type
- journal article
- Language
- en
- Open access
- gold
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- Hu, Y., Chen, J., Hu, G., Yu, J., Zhu, X., Lin, Y., Chen, S., & Yuan, J. (2015). Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012. Marine Drugs. https://doi.org/10.3390/md13010202
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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