Carotenoids in marine animals
Open accessAbstract
Marine animals contain various carotenoids that show structural diversity. These marine animals accumulate carotenoids from foods such as algae and other animals and modify them through metabolic reactions. Many of the carotenoids present in marine animals are metabolites of β-carotene, fucoxanthin, peridinin, diatoxanthin, alloxanthin, and astaxanthin, etc. Carotenoids found in these animals provide the food chain as well as metabolic pathways. In the present review, I will describe marine animal carotenoids from natural product chemistry, metabolism, food chain, and chemosystematic viewpoints, and also describe new structural carotenoids isolated from marine animals over the last decade.
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Spirulina contains unique natural antioxidants including polyphenols, carotenoids, and phycocyanin.
“Moreover, it also has considerable quantities of unique natural antioxidants including polyphenols, carotenoids, and phycocyanin.”
From Potential of Spirulina platensis as a feed supplement for poultry to enhance growth performance and immune modulation (2023) · cites this paper as [11]
Section 10 (page not provided) identifies zeaxanthin from spirulina and says carotenoids have antioxidative activity. It does not establish that spirulina contains considerable quantities of antioxidants or address its polyphenols or phycocyanin. (LLM, conf=0.88)
Experimental — accuracy not yet measuredSpirulina contains carotenoids (4000 mg/kg), including β-carotene and zeaxanthin.
“Spirulina also contains pigments, such as carotenoids (4000 mg/kg), which include β-carotene and zeaxanthin (10, 11), and chlorophyll pigments (12–14).”
From Potential of Spirulina platensis as a feed supplement for poultry to enhance growth performance and immune modulation (2023) · cites this paper as [11]
Section 10 (page unavailable) says zeaxanthin comes from spirulina, supporting that part of the claim. Our copy does not state that spirulina contains β-carotene or give a carotenoid concentration of 4000 mg/kg; searches for spirulina and that quantity found no such passage. (LLM, conf=0.88)
Experimental — accuracy not yet measured
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Cites
(2004) · doi:10.1007/978-3-0348-7836-4 · Cited by 652 · see citing works
Matsuno, T. (2001) · Fisheries Science · doi:10.1046/j.1444-2906.2001.00323.x · Cited by 375 · see citing works
Asai, A., Sugawara, T., Ono, H., & Nagao, A. (2004) · Drug Metabolism and Disposition · doi:10.1124/dmd.32.2.205 · Cited by 244 · see citing works
Hashimoto, T., Ozaki, Y., Taminato, M., Das, S. K., Mizuno, M., Yoshimura, K., Maoka, T., & Kanazawa, K. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114508199007 · Cited by 181 · see citing works
Self-citationRequirements for carotenoids in fish diets
Torrissen, O. J., & Christiansen, R. (1995) · Journal of Applied Ichthyology · doi:10.1111/j.1439-0426.1995.tb00022.x · Cited by 171 · see citing works
Effect of astaxanthin rich red yeast (Phaffia rhodozyma) on oxidative stress in rainbow trout
Nakano, T., Kanmuri, T., Sato, M., & Takeuchi, M. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(98)00145-7 · Cited by 150 · see citing works
Recent progress in structural studies of carotenoids in animals and plants
Maoka, T. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.10.019 · Cited by 127 · see citing works
Self-citationImprovement of Biochemical Features in Fish Health by Red Yeast and Synthetic Astaxanthin
Nakano, T., Tosa, M., & Takeuchi, M. (1995) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00054a029 · Cited by 115 · see citing works
The effect of dietary vitamin A and astaxanthin on the immunocompetence of rainbow trout
Thompson, I., Choubert, G., Houlihan, D. F., & Secombes, C. J. (1995) · Aquaculture · doi:10.1016/0044-8486(95)00024-v · Cited by 112 · see citing works
A Survey of Serum and Dietary Carotenoids in Captive Wild Animals
Slifka, K. A., Bowen, P. E., Stacewicz‐Sapuntzakis, M., & Crissey, S. D. (1999) · Journal of Nutrition · doi:10.1093/jn/129.2.380 · Cited by 95 · see citing works
The first isolation of enantiomeric and Meso-zeaxanthin in nature
Maoka, T., Arai, A., Shimizu, M., & Matsuno, T. (1986) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(86)90341-x · Cited by 94 · see citing works
Self-citationXanthophylls as precursors of retinoids
Matsuno, T. (1991) · Pure and Applied Chemistry · doi:10.1351/pac199163010081 · Cited by 94 · see citing works
Kawakami, T., Tsushima, M., Katabami, Y., Mine, M., Ishida, A., & Matsuno, T. (1998) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/s0022-0981(97)00236-0 · Cited by 80 · see citing works
Absorption and metabolism of carotenoids in birds, fish and crustaceans
Schiedt, K. (1998) · Cited by 80 · see citing works
Reductive metabolic pathways of carotenoids in fish (3S,3′S)-astaxanthin to tunaxanthin a, b and c
Matsuno, T., 勝山, 政., Maoka, T., Hirono, T., & Komori, T. (1985) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(85)90461-4 · Cited by 63 · see citing works
Self-citationThe role of carotenoids in the development of the sea urchin Pseudocentrotus depressus
TSUSHLMA, M., Kawakami, T., Mine, M., & Matsuno, T. (1997) · Invertebrate Reproduction & Development · doi:10.1080/07924259.1997.9672616 · Cited by 53 · see citing works
Matsuno, T., Ookubo, M., & Komori, T. (1985) · Journal of Natural Products · doi:10.1021/np50040a015 · Cited by 50 · see citing works
Maoka, T., Fujiwara, Y., Hashimoto, K., & Akimoto, N. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf058088t · Cited by 46 · see citing works
Self-citationMatsuno, T., Ookubo, M., NISHIZAWA, T., & SHIMIZU, I. (1984) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.32.4309 · Cited by 45 · see citing works
Structures of Five New Carotenoids from the Oyster Crassostrea gigas
Maoka, T., Hashimoto, K., Akimoto, N., & Fujiwara, Y. (2001) · Journal of Natural Products · doi:10.1021/np000476w · Cited by 44 · see citing works
Self-citationCharacterization of Fucoxanthin and Fucoxanthinol Esters in the Chinese Surf Clam, Mactra chinensis
Maoka, T., Fujiwara, Y., Hashimoto, K., & Akimoto, N. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf063139n · Cited by 41 · see citing works
Self-citationYamashita, E., Arai, S., & Matsuno, T. (1996) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/0305-0491(95)02069-1 · Cited by 29 · see citing works
Crassostreaxanthins A and B, novel marine carotenoids from the oyster
Fujiwara, Y., Maoka, T., Ookubo, M., & Matsuno, T. (1992) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)61240-6 · Cited by 27 · see citing works
Self-citationTsushima, M., Fujiwara, Y., & Matsuno, T. (1996) · Journal of Natural Products · doi:10.1021/np960022s · Cited by 27 · see citing works
New C37 Skeletal Carotenoid from the Clam, Paphia amabillis
Maoka, T., Akimoto, N., Yim, M., Hosokawa, M., & Miyashita, K. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf802717b · Cited by 27 · see citing works
Self-citationA Cytotoxic Carotenoid from the Marine Sponge Prianos osiros
Rogers, E. W., & Molinski, T. F. (2005) · Journal of Natural Products · doi:10.1021/np0497797 · Cited by 26 · see citing works
Comparative biochemical studies of carotenoids in catfishes
Tsushima, M. (2002) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s1096-4959(02)00159-8 · Cited by 26 · see citing works
Krinsky, N. I., Mathews‐Roth, M. M., & Taylor, R. F. (1989) · Springer eBooks · doi:10.1007/978-1-4613-0849-2 · Cited by 25 · see citing works
Ophioxanthin, a new marine carototenoid sulphate from the ophiuroid
D’Auria, M. V., Riccio, R., & Minale, L. (1985) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)94760-9 · Cited by 23 · see citing works
Structure of Minor Carotenoids from the Crown-of-Thorns Starfish, Acanthaster planci
Maoka, T., Akimoto, N., Terada, Y., Komemushi, S., Harada, R., Sameshima, N., & Sakagami, Y. (2010) · Journal of Natural Products · doi:10.1021/np100021u · Cited by 22 · see citing works
Self-citationCarotenoids in Clams, Ruditapes philippinarum and Meretrix petechialis
Maoka, T., Akimoto, N., Murakoshi, M., Sugiyama, K., & Nishino, H. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf1006243 · Cited by 20 · see citing works
Self-citationStructures of Carotenoids with 5,6-Dihydro-β-End Groups from the Spindle Shell Fusinus perplexus
Tsushima, M., Maoka, T., & Matsuno, T. (2001) · Journal of Natural Products · doi:10.1021/np010060y · Cited by 20 · see citing works
Self-citationLiaaen-Jensen, S., Britton, G., & Liaaen-Jensen, S. (1998) · Cited by 19 · see citing works
Structure of New Carotenoids from Corbicula Clam Corbicula japonica
Maoka, T., Fujiwara, Y., Hashimoto, K., & Akimoto, N. (2005) · Journal of Natural Products · doi:10.1021/np058053n · Cited by 19 · see citing works
Self-citationOccurrence of 9′Z-β-Echinenone in the Sea Urchin Pseudocentrotus depressus
Tsushima, M., & Matsuno, T. (1997) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s0305-0491(97)00302-7 · Cited by 18 · see citing works
Tushima, M., Maoka, T., & Matsuno, T. (1989) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(89)90393-3 · Cited by 18 · see citing works
Self-citationFerreres, F., Pereira, D. M., Gil‐Izquierdo, Á., Valentão, P., Botelho, J., Mouga, T., & Andrade, P. B. (2010) · Journal of Separation Science · doi:10.1002/jssc.201000197 · Cited by 18 · see citing works
Matsuno, T., Tsushima, M., & Maoka, T. (2001) · Journal of Natural Products · doi:10.1021/np0004294 · Cited by 17 · see citing works
Self-citationA new apocarotenoid from the sea hare Aplysia kurodai
Yamashita, E., & Matsuno, T. (1990) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(90)90041-q · Cited by 17 · see citing works
Structure of New Carotenoids with a 3,4-Dihydroxy-.BETA.-End Group from the Oyster Crassostrea gigas
Maoka, T., Fujiwara, Y., Hashimoto, K., & Akimoto, N. (2005) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.53.1207 · Cited by 16 · see citing works
Self-citationTsushima, M., Mune, E., Maoka, T., & Matsuno, T. (2000) · Journal of Natural Products · doi:10.1021/np990580h · Cited by 16 · see citing works
Self-citationA New Apocarotenoid from the Marine Shellfish Mytilus coruscus
Maoka, T. (1997) · Journal of Natural Products · doi:10.1021/np970039q · Cited by 13 · see citing works
Self-citationFirst total synthesis of crassostreaxanthin B
Tode, C., Yamano, Y., & Ito, M. (1999) · Journal of the Chemical Society Perkin Transactions 1 · doi:10.1039/a901116a · Cited by 13 · see citing works
Structures of Minor Carotenoids from the Japanese Common Catfish, Silurus asotus
Maoka, T., & Akimoto, N. (2011) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.59.140 · Cited by 11 · see citing works
Self-citationMaoka, T., & Akimoto, N. (2006) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.54.1462 · Cited by 6 · see citing works
Self-citationTode, C., Yamano, Y., & Ito, M. (2001) · Journal of the Chemical Society Perkin Transactions 1 · doi:10.1039/b108037g · Cited by 4 · see citing works
Isolation of purple nor-carotenoid, 2', 3'-dihydroroserythrin, from crawfish Procambarus clarkii
Maoka, T., & Ando, S. (2007) · Fisheries Science · doi:10.1111/j.1444-2906.2007.01422.x · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
3 of the 50 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- [8]Matsuno T. Animal carotenoids Carotenoids Chemistry and Biology Krinsky N.I. Mathews-Roth M.M. Taylor R.F. Plenum Press New York, NY, USA 1989 59 74
- [9]Matsuno T. Hirao S. Marine carotenoids Marine Biogenic Lipids, Fats, and Oils Ackman R.G. CRC Press Boca Raton, FL, USA 1989 1 251 388
- [23]Tode C. Yamano Y. Ito M. Carotenoids and related polyenes. Part 7. Total synthesis of crassostreaxanthin B Applying the stereoselective rearrangement of tetrasubstituted epoxides J. Chem. Soc., Perkin Trans. 2001 1 3338 3345
Cited by
Sorted by citations
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,880 · see citing works
Carotenoids as natural functional pigments
Maoka, T. (2019) · Journal of Natural Medicines · doi:10.1007/s11418-019-01364-x · Cited by 1,323 · see citing works
Self-citationRodrı́guez-Concepción, M., Ávalos, J., Bonet, M. L., Boronat, A., Gómez‐Gómez, L., Hornero‐Méndez, D., Limón, M. C., Meléndez‐Martínez, A. J., Olmedilla‐Alonso, B., Palou, A., et al. (2018) · Progress in Lipid Research · doi:10.1016/j.plipres.2018.04.004 · Cited by 1,034 · see citing works
The Various Roles of Fatty Acids
de Carvalho, C. C. C. R., & Caramujo, M.-J. (2018) · Molecules · doi:10.3390/molecules23102583 · Cited by 927 · see citing works
Peng, J., Yuan, J.-P., Wu, C.-F., & Wang, J.-H. (2011) · Marine Drugs · doi:10.3390/md9101806 · Cited by 820 · see citing works
Bernstein, P. S., Li, B., Vachali, P. P., Gorusupudi, A., Shyam, R., Henriksen, B. S., & Nolan, J. M. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.10.003 · Cited by 558 · see citing works
Blunt, J. W., Copp, B. R., Keyzers, R. A., Munro, M. H. G., & Prinsep, M. R. (2012) · Natural Product Reports · doi:10.1039/c2np20112g · Cited by 518 · see citing works
Carotenoids from Marine Organisms: Biological Functions and Industrial Applications
Galasso, C., Corinaldesi, C., & Sansone, C. (2017) · Antioxidants · doi:10.3390/antiox6040096 · Cited by 430 · see citing works
Functional properties of carotenoids originating from algae
Christaki, E., Bonos, E., Giannenas, I., & Florou‐Paneri, P. (2013) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.5902 · Cited by 346 · see citing works
Meléndez‐Martínez, A. J., Mandić, A., Bantis, F., Böhm, V., Borge, G. I. A., Brnčić, M., Bysted, A., Cano, M. P., Dias, M. D. G., Elgersma, A., et al. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1867959 · Cited by 351 · see citing works
Macroalgae as a sustainable aquafeed ingredient
Wan, A. H. L., Davies, S. J., Soler‐Vila, A., Fitzgerald, R., & Johnson, M. P. (2019) · Reviews in Aquaculture · doi:10.1111/raq.12241 · Cited by 292 · see citing works
Rhodotorula glutinis—potential source of lipids, carotenoids, and enzymes for use in industries
Kot, A. M., Błażejak, S., Kurcz, A., Gientka, I., & Kieliszek, M. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7611-8 · Cited by 288 · see citing works
Meléndez‐Martínez, A. J. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801045 · Cited by 263 · see citing works
Applications of microalga <i>Chlorella vulgaris</i> in aquaculture
Ahmad, M. T., Shariff, M., Md. Yusoff, F., Goh, Y. M., & Banerjee, S. (2020) · Reviews in Aquaculture · doi:10.1111/raq.12320 · Cited by 244 · see citing works
Böhm, V., Lietz, G., Olmedilla‐Alonso, B., Phelan, D., Reboul, E., Bánáti, D., Borel, P., Corte‐Real, J., de Lera, Á. R., Desmarchelier, C., et al. (2020) · Nutrition Reviews · doi:10.1093/nutrit/nuaa008 · Cited by 234 · see citing works
A review of carotenoid utilisation and function in crustacean aquaculture
Wade, N. M., Gabaudan, J., & Glencross, B. D. (2015) · Reviews in Aquaculture · doi:10.1111/raq.12109 · Cited by 233 · see citing works
Meléndez‐Martínez, A. J., Stinco, C. M., & Mapelli‐Brahm, P. (2019) · Nutrients · doi:10.3390/nu11051093 · Cited by 234 · see citing works
Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging
Sztretye, M. T., Dienes, B., Gönczi, M., Czirják, T., Csernoch, L. J., László, A., Szentesi, P., & Keller-Pintér, A. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/3849692 · Cited by 218 · see citing works
Marine Microbial-Derived Molecules and Their Potential Use in Cosmeceutical and Cosmetic Products
Corinaldesi, C., Barone, G., Marcellini, F., Dell’Anno, A., & Danovaro, R. (2017) · Marine Drugs · doi:10.3390/md15040118 · Cited by 201 · see citing works
Carotenoids and their role in cancer prevention
Rowles, J. L., & Erdman, J. W. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158613 · Cited by 197 · see citing works
Kabir, M. T., Rahman, M. H., Shah, M., Jamiruddin, M. R., Basak, D., Al‐Harrasi, A., Bhatia, S., Ashraf, G. M., Najda, A., El-kott, A. F., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112610 · Cited by 184 · see citing works
de Carvalho, C. C. C. R., & Caramujo, M.-J. (2017) · Frontiers in Marine Science · doi:10.3389/fmars.2017.00093 · Cited by 179 · see citing works
Park, J. H., Lee, S. I., & Kim, I. H. (2018) · Poultry Science · doi:10.3382/ps/pey093 · Cited by 177 · see citing works
Astaxanthin: Past, Present, and Future
Nishida, Y., Berg, P., Shakersain, B., Hecht, K. A., Takikawa, A., Tao, R., Kakuta, Y., Uragami, C., Hashimoto, H., Misawa, N., et al. (2023) · Marine Drugs · doi:10.3390/md21100514 · Cited by 170 · see citing works
Self-citationElbahnaswy, S., & Elshopakey, G. E. (2023) · Fish Physiology and Biochemistry · doi:10.1007/s10695-022-01167-0 · Cited by 166 · see citing works
Rodrigues, E., Mariutti, L. R. B., & Mercadante, A. Z. (2012) · Marine Drugs · doi:10.3390/md10081784 · Cited by 141 · see citing works
Hama, S., Takahashi, K., Inai, Y., Shiota, K., Sakamoto, R. L., Yamada, A., Tsuchiya, H., Kanamura, K., Yamashita, E., & Kogure, K. (2012) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.23216 · Cited by 128 · see citing works
Ariizumi, T., Kishimoto, S., Kakami, R., Maoka, T., Hirakawa, H., Suzuki, Y., Ozeki, Y., Shirasawa, K., Bernillon, S., Okabe, Y., et al. (2014) · The Plant Journal · doi:10.1111/tpj.12570 · Cited by 127 · see citing works
Self-citationSelected Methods of Extracting Carotenoids, Characterization, and Health Concerns: A Review
Adadi, P., Barakova, N. V., & Krivoshapkina, E. F. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b01407 · Cited by 123 · see citing works
Astaxanthin as a Novel Mitochondrial Regulator: A New Aspect of Carotenoids, beyond Antioxidants
Nishida, Y., Nawaz, A., Hecht, K. A., & Tobe, K. (2021) · Nutrients · doi:10.3390/nu14010107 · Cited by 122 · see citing works
Šimat, V., Rathod, N. B., Čagalj, M., Hamed, I., & Mekinić, I. G. (2022) · Marine Drugs · doi:10.3390/md20030206 · Cited by 124 · see citing works
El-Shall, N. A., Jiang, S., Farag, M. R., Azzam, M., Al-Abdullatif, A. A., Alhotan, R., Dhama, K., Hassan, F.-U., & Alagawany, M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1072787 · Cited by 115 · see citing works
“Spirulina also contains pigments, such as carotenoids (4000 mg/kg), which include b-carotene and zeaxanthin (10, 11), and chlorophyll pigments (12–14).”
BackgroundMarine Bioactives and Their Application in the Food Industry: A Review
Senadheera, T. R. L., Hossain, A., & Shahidi, F. (2023) · Applied Sciences · doi:10.3390/app132112088 · Cited by 115 · see citing works
Carotenoid biofortification in crop plants: citius, altius, fortius
Zheng, X., Giuliano, G., & Al‐Babili, S. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158664 · Cited by 113 · see citing works
Microalgae for the prevention of cardiovascular disease and stroke
Raposo, M. F. D. J., & Morais, A. M. M. B. (2014) · Life Sciences · doi:10.1016/j.lfs.2014.09.018 · Cited by 109 · see citing works
Wang, S., Lv, J., Zhang, L., Dou, J., Sun, Y., Li, X., Fu, X., Dou, H., Mao, J., Hu, X., et al. (2015) · Open Biology · doi:10.1098/rsob.150130 · Cited by 107 · see citing works
Innovative Microalgae Pigments as Functional Ingredients in Nutrition
Christaki, E. V., Bonos, E., & Florou-Paneri, P. C. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800776-1.00014-5 · Cited by 103 · see citing works
Serini, S., Fasano, E., Piccioni, E., Cittadini, A. R. M., & Calviello, G. (2011) · Chemical Research in Toxicology · doi:10.1021/tx200314p · Cited by 102 · see citing works
Feasibility of the use of Spirulina in aquaculture diets
Rosas, V. T., Poersch, L., Romano, L. A., & Tesser, M. B. (2018) · Reviews in Aquaculture · doi:10.1111/raq.12297 · Cited by 100 · see citing works
Roles of Carotenoids in Invertebrate Immunology
Tan, K., Zhang, H., Lim, L., Ma, H., Li, S., & Zheng, H. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03041 · Cited by 98 · see citing works
Antioxidant properties evaluation of topical astaxanthin formulations as anti‐aging products
Eren, B., Tanrıverdi, S. T., Köse, F. A., & Özer, Ö. (2018) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.12665 · Cited by 94 · see citing works
Oxidative Stress and Marine Carotenoids: Application by Using Nanoformulations
Genç, Y., Bardakçı, H., Yücel, Ç., Karatoprak, G. Ş., Akkol, E. K., Barak, T. H., & Sobarzo‐Sánchez, E. (2020) · Marine Drugs · doi:10.3390/md18080423 · Cited by 94 · see citing works
Astaxanthin isomers: Selective distribution and isomerization in aquatic animals
Yu, W., & Liu, J. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.734915 · Cited by 92 · see citing works
Molecular Mechanisms of Astaxanthin as a Potential Neurotherapeutic Agent
Bahbah, E. I., Ghozy, S. A., Attia, M. S., Negida, A., Emran, T. B., Mitra, S., Albadrani, G. M., Abdel‐Daim, M. M., Uddin, M. S., & Simal‐Gándara, J. (2021) · Marine Drugs · doi:10.3390/md19040201 · Cited by 89 · see citing works
Mussagy, C. U., Khan, S., & Kot, A. M. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1908222 · Cited by 88 · see citing works
Mapelli‐Brahm, P., Gómez‐Villegas, P., Gonda, M., Léon-Vaz, A., León, R., Mildenberger, J., Rebours, C., Saravia, V., Vero, S., Vila, E., et al. (2023) · Marine Drugs · doi:10.3390/md21060340 · Cited by 95 · see citing works
Wei, Y., Shen, H., Xu, W., Pan, Y. J., Chen, J., Zhang, W., & Mai, K. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.734281 · Cited by 88 · see citing works
Algal Carotenoids: Chemistry, Sources, and Application
Mekinić, I. G., Šimat, V., Rathod, N. B., Hamed, I., & Čagalj, M. (2023) · Foods · doi:10.3390/foods12142768 · Cited by 89 · see citing works
Spirulina as a functional ingredient in broiler chicken diets
Bonos, E., Kasapidou, E., Kargopoulos, A., Karampampas, A., Christaki, E., Florou-Paneri, P. C., & Nikolakakis, I. (2016) · South African Journal of Animal Science · doi:10.4314/sajas.v46i1.12 · Cited by 86 · see citing works
Honda, M., Kageyama, H., Hibino, T., Zhang, Y., Diono, W., Kanda, H., Yamaguchi, R., Takemura, R., Fukaya, T., & Goto, M. (2019) · Molecules · doi:10.3390/molecules24112149 · Cited by 83 · see citing works
Scavenging of Hydroxyl Radicals in Aqueous Solution by Astaxanthin Encapsulated in Liposomes
Hama, S., Uenishi, S., Yamada, A., Ohgita, T., Tsuchiya, H., Yamashita, E., & Kogure, K. (2012) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00715 · Cited by 82 · see citing works
Bioaccessibility of Marine Carotenoids
Viera, I., Pérez‐Gálvez, A., & Roca, M. (2018) · Marine Drugs · doi:10.3390/md16100397 · Cited by 79 · see citing works
Potential Role of Natural Antioxidant Products in Oncological Diseases
Marino, P., Pepe, G., Basilicata, M. G., Vestuto, V., Marzocco, S., Autore, G., Procino, A., Gomez-Monterrey, I. M., Manfra, M., & Campiglia, P. (2023) · Antioxidants · doi:10.3390/antiox12030704 · Cited by 82 · see citing works
Marine algae colorants: Antioxidant, anti-diabetic properties and applications in food industry
Imchen, T., & Singh, K. S. (2022) · Algal Research · doi:10.1016/j.algal.2022.102898 · Cited by 83 · see citing works
Carneiro, W. F., Castro, T. F. D., Orlando, T. M., Meurer, F., Paula, D. A. D. J., Virote, B. D. C. R., Vianna, A. R. D. C. B., & Murgas, L. D. S. (2020) · Aquaculture · doi:10.1016/j.aquaculture.2020.735612 · Cited by 76 · see citing works
Kaga, K., Honda, M., Adachi, T., Honjo, M., Diono, W., Kanda, H., & Goto, M. (2018) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2018.02.008 · Cited by 76 · see citing works
Microbial carotenoid production and their potential applications as antioxidants: A current update
Joshi, K., Kumar, P., & Kataria, R. (2023) · Process Biochemistry · doi:10.1016/j.procbio.2023.02.020 · Cited by 75 · see citing works
Honda, M., Murakami, K., Osawa, Y., Kawashima, Y., Hirasawa, K., & Kuroda, I. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c00087 · Cited by 72 · see citing works
Bioaccessibility of carotenoids from plant and animal foods
Chacón-Ordóñez, T., Carle, R., & Schweiggert, R. M. (2018) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.9525 · Cited by 71 · see citing works
Novel phytonutrient contributors to antioxidant protection against cardiovascular disease
Riccioni, G., Speranza, L., Pesce, M., Cusenza, S., D’Orazio, N., & Glade, M. J. (2012) · Nutrition · doi:10.1016/j.nut.2011.11.028 · Cited by 71 · see citing works
Honda, M., Kageyama, H., Hibino, T., Sowa, T., & Kawashima, Y. (2019) · Process Biochemistry · doi:10.1016/j.procbio.2019.10.005 · Cited by 70 · see citing works
Ritu, J. R., Ambati, R. R., Ravishankar, G. A., Shahjahan, M., & Khan, S. (2022) · Journal of Applied Phycology · doi:10.1007/s10811-022-02817-9 · Cited by 67 · see citing works
Li, W., Zhang, Z.-M., Zhang, R., Jiao, H., Sun, A., Shi, X., & Chen, J. (2019) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.121241 · Cited by 64 · see citing works
Tan, K., Zhang, H., Lim, L., & Zheng, H. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.734769 · Cited by 63 · see citing works
Bernabé, P., Becherán, L., Cabrera‐Barjas, G., Nešić, A., Claudio Alburquenque, O., Tapia, C. V., Taboada, E., Alderete, J. B., & Ríos-Escalante, P. D. L. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.01.126 · Cited by 63 · see citing works
Synergistic antioxidative effect of astaxanthin and tocotrienol by co-encapsulated in liposomes
Kamezaki, C., Nakashima, A., Yamada, A., Uenishi, S., Ishibashi, H., Shibuya, N., Hama, S., Hosoi, S., Yamashita, E., & Kogure, K. (2016) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.15-153 · Cited by 63 · see citing works
Benefits under the Sea: The Role of Marine Compounds in Neurodegenerative Disorders
Catanesi, M., Caioni, G., Castelli, V., Benedetti, E., d’Angelo, M., & Cimini, A. (2021) · Marine Drugs · doi:10.3390/md19010024 · Cited by 61 · see citing works
Tsiaka, T., Zoumpoulakis, P. G., Sinanoglou, V. J., Makris, C., Heropoulos, G. A., & Calokerinos, A. C. (2015) · Analytica Chimica Acta · doi:10.1016/j.aca.2015.03.051 · Cited by 59 · see citing works
Sun, P., Wong, C.-C., Li, Y., He, Y., Mao, X., Wu, T., Ren, Y., & Chen, F. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.10.133 · Cited by 59 · see citing works
Progress in Carotenoid Research
Zepka, L. Q., Lopes, E. J., & de Rosso, V. V. (2018) · InTech eBooks · doi:10.5772/intechopen.73775 · Cited by 56 · see citing works
Astaxanthin biosynthesis promotion with pH shock in the green microalga, Haematococcus lacustris
Han, S., Chang, S., Lee, C.-S., Jeon, M. S., Heo, Y. M., Kim, S., & Choi, Y.-E. (2020) · Bioresource Technology · doi:10.1016/j.biortech.2020.123725 · Cited by 55 · see citing works
Potential natural carotenoid sources for the colouration of ornamental fish: a review
Sathyaruban, S., Uluwaduge, D. I., Yohi, S., & Kuganathan, S. (2021) · Aquaculture International · doi:10.1007/s10499-021-00689-3 · Cited by 63 · see citing works
Martins, B., Vieira, M., Delerue-Matos, C. M., Grosso, C., & Soares, C. M. D. (2022) · Marine Drugs · doi:10.3390/md20060362 · Cited by 56 · see citing works
Chemistry, Stability, and Biological Actions of Carotenoids
Yahia, E. M., Ornelas‐Paz, J. D. J., Emanuelli, T., Lopes, E. J., Zepka, L. Q., & Cervantes‐Paz, B. (2017) · doi:10.1002/9781119158042.ch15 · Cited by 54 · see citing works
Evaluation and improvement of storage stability of astaxanthin isomers in oils and fats
Honda, M., Kageyama, H., Hibino, T., Osawa, Y., Kawashima, Y., Hirasawa, K., & Kuroda, I. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.129371 · Cited by 52 · see citing works
Honda, M., Takasu, S., Nakagawa, K., & Tsuda, T. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.130119 · Cited by 52 · see citing works
Verification of Meso-Zeaxanthin in Fish
Nolan, J. M. (2014) · Journal of Food Processing & Technology · doi:10.4172/2157-7110.1000335 · Cited by 51 · see citing works
Turchini, G. M., Francis, D. S., Du, Z., Olsen, R. E., Ringø, E., & Tocher, D. R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819587-1.00003-3 · Cited by 50 · see citing works
Sustainable blue economy: Opportunities and challenges
Narwal, S., Kaur, M., Yadav, D. S., & Bast, F. (2024) · Journal of Biosciences · doi:10.1007/s12038-023-00375-x · Cited by 50 · see citing works
Antimicrobial components in the cocoon silk of silkworm, Bombyx mori
Dong, Z., Xia, Q., & Zhao, P. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.10.103 · Cited by 49 · see citing works
An extensive review of marine pigments: sources, biotechnological applications, and sustainability
Muñoz-Miranda, L. A., & Iñíguez-Moreno, M. (2023) · Aquatic Sciences · doi:10.1007/s00027-023-00966-8 · Cited by 49 · see citing works
Rashidian, G., Rainis, S., Prokić, M. D., & Faggio, C. (2020) · Natural Product Research · doi:10.1080/14786419.2020.1723091 · Cited by 49 · see citing works
Su, F., Yu, W., & Liu, J. (2020) · Aquaculture · doi:10.1016/j.aquaculture.2020.735146 · Cited by 47 · see citing works
Yang, M., Xuan, Z., Wang, Q., Yan, S., Zhou, D., Naman, C. B., Zhang, J., He, S., Yan, X., & Cui, W. (2021) · Nutritional Neuroscience · doi:10.1080/1028415x.2021.1926140 · Cited by 43 · see citing works
Guo, Z., Liu, Y., & Luo, Y. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2119204 · Cited by 43 · see citing works
Li, X., Bai, Z., Luo, H., Liu, Y., Wang, G., & Li, J. (2014) · Gene · doi:10.1016/j.gene.2014.01.046 · Cited by 43 · see citing works
Xu, M., Huang, J. L., Shi, Y., Zhang, H., & He, M. (2019) · BMC Genomics · doi:10.1186/s12864-019-5807-x · Cited by 43 · see citing works
Wang, C., Kim, J., & Kim, S.-W. (2014) · Marine Drugs · doi:10.3390/md12094810 · Cited by 43 · see citing works
Recent advances in amniote palaeocolour reconstruction and a framework for future research
Roy, A., Pittman, M., Saitta, E. T., Kaye, T. G., & Xu, X. (2019) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12552 · Cited by 40 · see citing works
Oxidative Stress in Pacific Salmon (Oncorhynchus spp.) during Spawning Migration
Wilson, S. M., Taylor, J. J., Mackie, T. A., Patterson, D. A., Cooke, S. J., & Willmore, W. G. (2014) · Physiological and Biochemical Zoology · doi:10.1086/674798 · Cited by 41 · see citing works
Mojib, N., Amad, M., Thimma, M., Aldanondo, N., Kumaran, M. K., & Irigoien, X. (2014) · Molecular Ecology · doi:10.1111/mec.12781 · Cited by 41 · see citing works
Li, Q., Zu, L., Cheng, Y., Wade, N. M., Liu, J., & Wu, X. (2020) · LWT · doi:10.1016/j.lwt.2020.109286 · Cited by 41 · see citing works
Marine-derived products as functional feed additives in aquaculture: A review
Doan, H. V., Prakash, P. S., Hoseinifar, S. H., Ringø, E., El‐Haroun, E., Faggio, C., Olsen, R. E., Tran, H. Q., Stejskal, V., Abdel‐Latif, H. M. R., et al. (2023) · Aquaculture Reports · doi:10.1016/j.aqrep.2023.101679 · Cited by 40 · see citing works
Honda, M., Sowa, T., & Kawashima, Y. (2020) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201900462 · Cited by 40 · see citing works
Zhang, C., Jin, Y., Yu, Y., Xiang, J., & Li, F. (2021) · Algal Research · doi:10.1016/j.algal.2021.102347 · Cited by 40 · see citing works
Nutrients and Bioactive Compounds in Seafood: Quantitative Literature Research Analysis
Durazzo, A., Lena, G. D., Gabrielli, P., Santini, A., Lombardi‐Boccia, G., & Lucarini, M. (2022) · Fishes · doi:10.3390/fishes7030132 · Cited by 39 · see citing works
Liao, Y., Zhang, B., Wang, D., Jiang, D., Zhu, C., Deng, S., Chen, H., Li, G., & Shi, H. (2025) · Reviews in Aquaculture · doi:10.1111/raq.70016 · Cited by 37 · see citing works
Honda, M., Sato, H., Takehara, M., Inoue, Y., Kitamura, C., Takemura, R., Fukaya, T., Diono, W., Kanda, H., & Goto, M. (2018) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201800060 · Cited by 37 · see citing works
Yu, X., Zhang, R., Liu, H., Zhang, Z., Shi, X., Sun, A., & Chen, J. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.129030 · Cited by 37 · see citing works
Colonese, A. C., Netto, S. A., Francisco, A. S., DeBlasis, P., Villagrán, X. S., Ponzoni, R. D. A. R., Hancock, Y., Hausmann, N., de Farias, D. S. E., Prendergast, A. L., et al. (2017) · Palaeogeography Palaeoclimatology Palaeoecology · doi:10.1016/j.palaeo.2017.01.006 · Cited by 36 · see citing works
- Authors
- Maoka, T.
- Affiliations
- Research Institute for Production Development (JP)
- Corresponding author
- Maoka, Takashi
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2011-02-22
- Volume
- 9
- Issue
- 2
- Pages
- 278-293
- ISSN
- 1660-3397 (ISSN-L)
- PMC
- PMC3093257
- OpenAlex
- W2075606591
- Cited by
- 413
- References
- 50
- Citations by year
- 2026: 25 · 2025: 33 · 2024: 36 · 2023: 31 · 2022: 42 · 2021: 40 · 2020: 44 · 2019: 31 · 2018: 31 · 2017: 24 · 2016: 19 · 2015: 13 · 2014: 21 · 2013: 6 · 2012: 12
- FWCI
- 1.28
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Marine Drugs (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Marine Sponges and Natural Products
- Keywords
- carotenoids, marine fauna, carotenoid metabolism, beta-carotene, fucoxanthin, peridinin, diatoxanthin, alloxanthin, astaxanthin, food chain, chemotaxonomy, structural diversity, marine natural products
- MeSH terms
- Animals, Biological Products, Carotenoids, Marine Biology, Food Chain
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