Pre-Discharge Predictors of 1-Year Rehospitalization in Adolescents and Young Adults with Severe Mental Disorders: A Retrospective Cohort Study
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Background and objectives: Readmissions of youths hospitalized for a severe mental disorder are common events and bear a remarkable human, social, and economic burden. The current study aimed at evaluating predictors of 1-year rehospitalization in a sample of adolescents and young adults with severe mental disorders. Materials and Methods: Data for ≤25-year-old inpatients with a severe mental disorder and consecutively admitted between 1 January 2016 and 30 June 2019 were collected. Subjects were retrospectively assessed over a follow-up period of one year after the index discharge to track readmissions—i.e., the primary outcome variable. Standard descriptive statistics were used. The association between variables and 1-year rehospitalization was estimated using the univariate Cox proportional hazards regression model. We then carried out a multivariable Cox regression model, also estimating the covariate-adjusted survivor function. Hazard ratios (HRs) with related 95% confidence intervals (95% CIs) were provided. Results: The final sample included 125 individuals. The multivariable Cox regression model estimated that co-occurring substance use disorders (HR = 2.14; 95% CI: 1.08 to 4.26; p = 0.029) and being admitted for a suicide attempt (HR = 2.49; 95% CI: 1.13 to 5.49; p = 0.024) were both significant predictors of 1-year rehospitalization. Conclusions: Our study showed that comorbid substance use disorders and being admitted for a suicide attempt were predictors of early readmission in youths with severe mental disorders. Although their generalizability is limited, our findings could contribute to improve the quality of young patients’ mental health care by identifying vulnerable subjects who may benefit from tailored interventions to prevent rehospitalizations.
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Destructive experiential avoidance behaviors in adolescents increase the public health burden, such as rehospitalizations and emergency department visits.
“As previous studies indicated, DEA behaviors in adolescents also increase the public health burden, such as rehospitalizations and emergency department visits [16,17].”
From Acceptance and Commitment Therapy for Destructive Experiential Avoidance (ACT-DEA): A Feasibility Study (2022) · cites this paper as [16]
The Discussion (§4.1) reports that substance use disorders and admission after a suicide attempt predicted rehospitalization among adolescents and young adults with severe mental disorders. The paper does not classify these as destructive experiential avoidance behaviors or report emergency department visits, and its findings do not extend to adolescents generally. (LLM, conf=0.88)
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Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040296 · Cited by 23,020 · see citing works
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., & Vandenbroucke, J. P. (2008) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2007.11.008 · Cited by 17,893 · see citing works
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-8-200710160-00010 · Cited by 17,796 · see citing works
(2007) · PubMed Central · Cited by 2,521 · see citing works
Suicide and suicidal behaviour
Turecki, G., & Brent, D. A. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00234-2 · Cited by 2,338 · see citing works
Variable selection strategies and its importance in clinical prediction modelling.
Chowdhury, M. Z. I., & Turin, T. C. (2020) · Family Medicine and Community Health · doi:10.1136/fmch-2019-000262 · Cited by 1,011 · see citing works
Review: Suicide and schizophrenia: a systematic review of rates and risk factors
Hor, K., & Taylor, M. (2010) · Journal of Psychopharmacology · doi:10.1177/1359786810385490 · Cited by 853 · see citing works
Use of administrative medical databases in population-based research
Gavrielov‐Yusim, N., & Friger, M. D. (2013) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2013-202744 · Cited by 264 · see citing works
A systematic review of psychosocial suicide prevention interventions for youth
Calear, A. L., Christensen, H. M., Freeman, A., Fenton, K., Grant, J. B., van Spijker, B. A. J., & Donker, T. (2015) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-015-0783-4 · Cited by 215 · see citing works
Donisi, V., Tedeschi, F., Wahlbeck, K., Haaramo, P., & Amaddeo, F. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1114-0 · Cited by 166 · see citing works
Singh, S. P., & Tuomainen, H. (2015) · World Psychiatry · doi:10.1002/wps.20266 · Cited by 163 · see citing works
Substance abuse and suicide risk among adolescents
Pompili, M., Serafini, G., Innamorati, M., Biondi, M., Siracusano, A., Giannantonio, M. D., Giupponi, G., Amore, M., Lester, D., Girardi, P., et al. (2012) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-012-0292-0 · Cited by 154 · see citing works
Mounteney, J., Griffiths, P., Sedefov, R., Noor, A., Vicente, J., & Simon, R. (2015) · Addiction · doi:10.1111/add.13056 · Cited by 137 · see citing works
Fontanella, C. A. (2008) · American Journal of Orthopsychiatry · doi:10.1037/a0012557 · Cited by 134 · see citing works
Carrà, G., Bartoli, F., Crocamo, C., Brady, K. T., & Clerici, M. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.05.066 · Cited by 125 · see citing works
Self-citationVerdoux, H., Liraud, F., Gonzalès, B., Assens, F., Abalan, F., & van Os, J. (2001) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2001.00202.x · Cited by 110 · see citing works
A note on the magnitude of hazard ratios
Azuero, A. (2016) · Cancer · doi:10.1002/cncr.29924 · Cited by 95 · see citing works
Rumball‐Smith, J., & Hider, P. N. (2009) · PubMed · Cited by 85 · see citing works
MacDonald, L., Chapman, S., Syrett, M., Bowskill, R., & Horne, R. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.01.002 · Cited by 80 · see citing works
Carrà, G., Sciarini, P., Lusignani, G. S., Clerici, M., Montomoli, C., & Kessler, R. C. (2010) · European Psychiatry · doi:10.1016/j.eurpsy.2010.04.008 · Cited by 78 · see citing works
Self-citationKalseth, J., Lassemo, E. I., Wahlbeck, K., Haaramo, P., & Magnussen, J. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1099-8 · Cited by 77 · see citing works
Psychiatric readmission of children and adolescents: a systematic review and meta-analysis.
Edgcomb, J. B., Sorter, M., Lorberg, B., & Zima, B. T. (2020) · Psychiatric Services · doi:10.1176/appi.ps.201900234 · Cited by 77 · see citing works
Measuring Pediatric Hospital Readmission Rates to Drive Quality Improvement
Nakamura, M., Toomey, S. L., Zaslavsky, A. M., Berry, J. G., Lorch, S. A., Jha, A. K., Bryant, M. C., Geanacopoulos, A. T., Loren, S. S., Pain, D., et al. (2014) · Academic Pediatrics · doi:10.1016/j.acap.2014.06.012 · Cited by 73 · see citing works
Ostuzzi, G., Mazzi, M. A., Terlizzi, S., Bertolini, F., Aguglia, A., Bartoli, F., Bortolaso, P., Callegari, C., Caroleo, M., Carrà, G., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0201371 · Cited by 68 · see citing works
Self-citationSuicidal ideation and substance use among adolescents and young adults: A bidirectional relation?
Zhang, X., & Wu, L.-T. T. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.05.025 · Cited by 63 · see citing works
Comorbid Addiction and Major Mental Illness in Europe: A Narrative Review
Carrà, G., Bartoli, F., Brambilla, G., Crocamo, C., & Clerici, M. (2014) · Substance Abuse · doi:10.1080/08897077.2014.960551 · Cited by 60 · see citing works
Self-citationCarrà, G., Johnson, S., Crocamo, C., Angermeyer, M. C., Brugha, T. S., Azorin, J., Toumi, M., & Bebbington, P. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.03.038 · Cited by 58 · see citing works
Self-citationThe prevalence of metabolic syndrome in people with severe mental illness: a mediation analysis
Carrà, G., Bartoli, F., Carretta, D., Crocamo, C., Bozzetti, A., Clerici, M., & Bebbington, P. (2014) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-014-0835-y · Cited by 57 · see citing works
Self-citationCarrà, G., Scioli, R., Monti, M. C., & Marinoni, A. (2006) · European Addiction Research · doi:10.1159/000090429 · Cited by 55 · see citing works
Self-citationCannabis use disorder and suicide attempts in bipolar disorder: A meta-analysis
Bartoli, F., Crocamo, C., & Carrà, G. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.05.017 · Cited by 52 · see citing works
Self-citationDell’Osso, B., Albert, U., Carrà, G., Pompili, M., Nanni, M. G., Pasquini, M., Poloni, N., Raballo, A., Sambataro, F., Serafini, G., et al. (2020) · Annals of General Psychiatry · doi:10.1186/s12991-020-00306-2 · Cited by 52 · see citing works
Self-citationPredictors of Rehospitalization for Depressed Adolescents Admitted to Acute Psychiatric Treatment
van Alphen, N. R., Stewart, J. G., Esposito, E. C., Pridgen, B. C., Gold, J., & Auerbach, R. P. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m10326 · Cited by 50 · see citing works
Bartoli, F., Crocamo, C., Dakanalis, A., Riboldi, I., Miotto, A., Brosio, E., Clerici, M., & Carrà, G. (2017) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.11.035 · Cited by 48 · see citing works
Self-citationRuggeri, M., Lora, A., & Semisa, D. (2008) · Epidemiology and Psychiatric Sciences · doi:10.1017/s1121189x00000154 · Cited by 45 · see citing works
Factors Associated With Multiple Psychiatric Readmissions for Youth With Mood Disorders
Phillips, M. S., Steelesmith, D. L., Campo, J. V., Pradhan, T., & Fontanella, C. A. (2019) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2019.05.024 · Cited by 41 · see citing works
Patient-Level Predictors of Psychiatric Readmission in Substance Use Disorders
Böckmann, V., Lay, B., Seifritz, E., Kawohl, W., Roser, P., & Habermeyer, B. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00828 · Cited by 41 · see citing works
Carrà, G., Crocamo, C., Borrelli, P., Popa, I., Ornaghi, A., Montomoli, C., & Clerici, M. (2014) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2014.11.021 · Cited by 40 · see citing works
Self-citationColizzi, M., Burnett, N., Costa, R., Agostini, M. D., Griffin, J., & Bhattacharyya, S. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.08.005 · Cited by 37 · see citing works
Madden, A., Vajda, J., Llamocca, E. N., Campo, J. V., Gorham, T. J., Lin, S. M., & Fontanella, C. A. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2020.05.004 · Cited by 33 · see citing works
Landolt, K., Rössler, W., Ajdacic-Gross, V., Derks, E. M., Libiger, J., Kahn, R. S., & Fleischhacker, W. W. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.01.046 · Cited by 28 · see citing works
Longitudinal examination of youth readmission to mental health inpatient units
Miller, D. A. A., Ronis, S. T., Slaunwhite, A., Audas, R., Richard, J., Tilleczek, K. C., & Zhang, M. (2020) · Child and Adolescent Mental Health · doi:10.1111/camh.12371 · Cited by 28 · see citing works
Carrà, G., Crocamo, C., Borrelli, P., Tabacchi, T., Bartoli, F., Popa, I., Montomoli, C., & Clerici, M. (2016) · Substance Use & Misuse · doi:10.1080/10826084.2016.1240696 · Cited by 25 · see citing works
Self-citationClinical and organizational factors predicting readmission for mental health patients across Italy
Tedeschi, F., Donisi, V., Salazzari, D., Cresswell‐Smith, J., Wahlbeck, K., & Amaddeo, F. (2019) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-019-01766-y · Cited by 17 · see citing works
Reducing Psychiatric Inpatient Readmissions Using an Organizational Change Model.
Molfenter, T. D., Connor, T., Jh, F., Hyatt, J., & Zimmerman, D. (2016) · PubMed · Cited by 12 · see citing works
Rezai-Zadeh, K. P., Engstrom, R. N., Sharma, A., Chen, Y., Chu, J., Cox, R. P., & Lee, M. T. (2018) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2018.10.010 · Cited by 8 · see citing works
Bartoli, F., Lev‐Ran, S., Crocamo, C., & Carrà, G. (2018) · BOA (University of Milano-Bicocca) · Cited by 7 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Yang, Q., Hu, Y., Zeng, Z., Liu, S.-J., Wu, T., & Zhang, G.-H. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192315895 · Cited by 51 · see citing works
Jiang, Z., Wang, Z., Diao, Q., Chen, J., Tian, G., Cheng, X., Zhao, M., He, L., He, Q., Sun, J., et al. (2022) · Annals of General Psychiatry · doi:10.1186/s12991-022-00423-0 · Cited by 43 · see citing works
Bartoli, F., Bachi, B., Calabrese, A., Cioni, R. M., Guzzi, P., Nasti, C., Palpella, D., Barbieri, F. F., Limonta, S., Crocamo, C., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.08.096 · Cited by 24 · see citing works
Self-citationBartoli, F., Bachi, B., Callovini, T., Palpella, D., Piacenti, S., Morreale, M., Lella, M. E. D., Crocamo, C., Carrà, G., & NOMIAC Investigators (2023) · CNS Spectrums · doi:10.1017/s1092852923002377 · Cited by 23 · see citing works
Self-citationNa, E., Lee, K., Jeon, B.-H., Jo, C., Kwak, U.-H., Jeon, Y., Yang, K., Lee, E. J., & Jeong, J. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192416434 · Cited by 21 · see citing works
“As previous studies indicated, DEA behaviors in adolescents also increase the public health burden, such as rehospitalizations and emergency department visits [16,17].”
ResultKwon, R., Lee, H., Kim, M. S., Lee, J., & Yon, D. K. (2023) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2023.103704 · Cited by 20 · see citing works
Hsu, C. J., Ayres, A. C., & Payne, L. (2024) · Early Intervention in Psychiatry · doi:10.1111/eip.13499 · Cited by 16 · see citing works
Bürgin, D., Clemens, V., Varghese, N., Eckert, A., Huber, M., Bruttin, E., Boonmann, C., Unternährer, E., O'Donovan, A., & Schmid, M. (2022) · Brain, Behavior, & Immunity - Health · doi:10.1016/j.bbih.2022.100524 · Cited by 14 · see citing works
Predictors of Length of Hospitalization and Impact on Early Readmission for Mental Disorders
Gentil, L., Grenier, G., Vasiliadis, H., & Fleury, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192215127 · Cited by 17 · see citing works
Arafat, S. M. Y., Hussain, F., Zaman, M. S., Tabassum, T., Islam, M. K., Shormi, F. R., Khan, A. R., Islam, M. R., Redwan, A. S. M., Giasuddin, N. A., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1025976 · Cited by 13 · see citing works
Bartoli, F., Callovini, T., Calabrese, A., Cioni, R., Riboldi, I., Crocamo, C., & Carrà, G. (2021) · Brain Science · doi:10.3390/brainsci12010038 · Cited by 12 · see citing works
Self-citationMoçambique, M. A. T. M., Hoffmann, A., Roglio, V. S., Kessler, F. H. P., Dalbosco, C., Schuch, J. B., & Pechansky, F. (2022) · Brazilian Journal of Psychiatry · doi:10.47626/1516-4446-2021-2207 · Cited by 12 · see citing works
Bansema, C. H., Vermeiren, R. R. J. M., de Soet, R., van Ewijk, H., Nijland, L., & Nooteboom, L. A. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02216-6 · Cited by 11 · see citing works
Factors affecting readmission of adolescent mental healthcare users to a psychiatric hospital
Eichstadt, S. A., Chetty, S., Magagula, T. G., & Swart, X. (2023) · South African Journal of Psychiatry · doi:10.4102/sajpsychiatry.v29i0.2110 · Cited by 4 · see citing works
Cognitive Profiles of Adolescent Inpatients with Substance Use Disorder
Becker, A., Lüken, L., Kelker, L., Holtmann, M., Daseking, M., & Legenbauer, T. (2022) · Children · doi:10.3390/children9050756 · Cited by 4 · see citing works
Poursaadati, M. Z., Hosseinzadeh, S., Maarefvand, M., Bolhari, J., & Khubchandani, J. (2023) · Epidemiologia · doi:10.3390/epidemiologia4010008 · Cited by 2 · see citing works
Fleury, M., Cao, Z., Grenier, G., & LESAGE, A. D. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115093 · Cited by 1 · see citing works
Ratner, Y., & Ritsner, M. S. (2021) · Acta Scientific Neurology · doi:10.31080/asne.2021.04.0449 · Cited by 1 · see citing works
Şahin, N., & Özkan, B. (2025) · ALPHA PSYCHIATRY · doi:10.31083/ap39445
Predictors of readmission in child and adolescent psychiatry
Padilla, F. M., Lingamchetty, T. N., Waxmonsky, J. G., & Baweja, R. (2026) · World Journal of Psychiatry · doi:10.5498/wjp.v16.i3.113468
- Authors
- Bartoli, F., Cavaleri, D., Moretti, F., Bachi, B., Calabrese, A., Callovini, T., Cioni, R. M., Riboldi, I., Nacinovich, R., Crocamo, C., & Carrà, G.
- Affiliations
- University of Milano-Bicocca (IT)
- University College London (GB)
- Corresponding author
- Bartoli, Francesco
- ORCID
- Venue
- Medicina
- Publisher
- MDPI AG
- Published
- 2020-11-15
- Volume
- 56
- Issue
- 11
- Pages
- 613
- ISSN
- 1010-660X (ISSN-L)
- 1648-9144
- PMC
- PMC7696058
- OpenAlex
- W3098143157
- Cited by
- 20
- References
- 47
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 6 · 2022: 9 · 2021: 2
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Medicina (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- hospital readmission, adolescents, young adults, severe mental illness, substance use disorders, suicide attempts, predictors of readmission, psychiatric inpatient care, comorbidities
- MeSH terms
- Adolescent, Adult, Hospitalization, Humans, Patient Discharge, Patient Readmission, Retrospective Studies, Risk Factors, Suicide, Attempted, Young Adult
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