The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Vitamin D Sources, Metabolism, and Deficiency: Available Compounds and Guidelines for Its Treatment
Open accessAbstract
Studies on vitamin/hormone D deficiency have received a vast amount of attention in recent years, particularly concerning recommendations, guidelines, and treatments. Moreover, vitamin D’s role as a hormone has been confirmed in various enzymatic, metabolic, physiological, and pathophysiological processes related to many organs and systems in the human body. This growing interest is mostly due to the evidence that modest-to-severe vitamin D deficiency is widely prevalent around the world. There is broad agreement that optimal vitamin D status is necessary for bones, muscles, and one’s general health, as well as for the efficacy of antiresorptive and anabolic bone-forming treatments. Food supplementation with vitamin D, or the use of vitamin D supplements, are current strategies to improve vitamin D levels and treat deficiency. This article reviews consolidated and emerging concepts about vitamin D/hormone D metabolism, food sources, deficiency, as well as the different vitamin D supplements available, and current recommendations on the proper use of these compounds.
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“In athletes, insufficient vitamin D levels have been linked to diminished muscle strength, slower recovery rates, and increased injury rates (9).”
From The decline of vitamin D in adolescent athletes: insights from a one-year follow-up and its association with electrocardiographic changes (2025) · cites this paper as [9]
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Holick, M. F. (2007) · New England Journal of Medicine · doi:10.1056/nejmra070553 · Cited by 13,720
Martineau, A. R., Jolliffe, D. A., Hooper, R. L., Greenberg, L., Aloia, J. F., Bergman, P., Dubnov-Raz, G., Esposito, S., Ganmaa, D., Ginde, A. A., et al. (2017) · BMJ · doi:10.1136/bmj.i6583 · Cited by 2,040 · cited 1×
“When participants were stratified by vitamin D status, those with baseline 25(OH)D below 10 ng/mL had a stronger risk reduction when using supplementation on a daily or weekly doses, but not in those receiving large doses, which has been associated with adverse skeletal effects [5,75].”
BackgroundVitamin D for health: a global perspective
Hossein-nezhad, A., & Holick, M. F. (2013) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2013.05.011 · Cited by 1,298
Regulation of Phosphate Homeostasis by PTH, Vitamin D, and FGF23
Bergwitz, C., & Jüppner, H. (2010) · Annual Review of Medicine · doi:10.1146/annurev.med.051308.111339 · Cited by 741
Vitamin D bioavailability: state of the art
Borel, P., Caillaud, D., & Cano, N. J. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2012.688897 · Cited by 378
Prevalence of vitamin D inadequacy in athletes: a systematic-review and meta-analysis
Farrokhyar, F., Tabasinejad, R., Dao, D., Peterson, D., Ayeni, O. R., Hadioonzadeh, R., & Bhandari, M. (2015) · Sports Medicine · doi:10.1007/s40279-014-0267-6 · Cited by 249
Muscular effects of vitamin D in young athletes and non-athletes and in the elderly
Koundourakis, N. E., Avgoustinaki, P. D., Malliaraki, N., & Margioris, A. N. (2016) · Hormones · doi:10.14310/horm.2002.1705 · Cited by 109
Cited by
Voulgaridou, G., Papadopoulou, S. K., Detopoulou, P., Tsoumana, D., Giaginis, C., Kondyli, F. S., Lymperaki, E., & Pritsa, A. (2023) · Diseases · doi:10.3390/diseases11010029 · Cited by 135
The Impact of Vitamin D on Androgens and Anabolic Steroids among Adult Males: A Meta-Analytic Review
Abu-Zaid, A., Saleh, S. A. K., Adly, H. M., Baradwan, S., Alharran, A. M., Alhatm, M., Alzayed, M. M., Alotaibi, M. N., Saad, A. R., Alfayadh, H. M., et al. (2024) · Diseases · doi:10.3390/diseases12100228 · Cited by 11
Ramadan, M. M., Jaber, A. A., Aladwani, A. J., Alayyaf, A. E., Sayed-Noor, A. S., Ghanem, H. B., El-Sherbiny, M., Ebrahim, H. A., Ahmed, M. M., & Elsherbini, D. M. A. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1731919 · Cited by 1
Metadata
- Authors
- Dominguez, L. J., Farruggia, M., Veronese, N., & Barbagallo, M.
- Venue
- Metabolites
- Publisher
- MDPI AG
- Published
- 2021-04-20
- Volume
- 11
- Issue
- 4
- Pages
- 255
- ISSN
- 2218-1989 (ISSN-L)
- OpenAlex
- W3154417399
- Cited by
- 299
- References
- 7
- FWCI
- 26.08
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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