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Cited by 559

The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.

Hydrogels Based on Schiff Base Linkages for Biomedical Applications

Open access
Xu, Junpeng, Liu, Yi, Hsu, Shan-hui·2019·Molecules

Abstract

Schiff base, an important family of reaction in click chemistry, has received significant attention in the formation of self-healing hydrogels in recent years. Schiff base reversibly reacts even in mild conditions, which allows hydrogels with self-healing ability to recover their structures and functions after damages. Moreover, pH-sensitivity of the Schiff base offers the hydrogels response to biologically relevant stimuli. Different types of Schiff base can provide the hydrogels with tunable mechanical properties and chemical stabilities. In this review, we summarized the design and preparation of hydrogels based on various types of Schiff base linkages, as well as the biomedical applications of hydrogels in drug delivery, tissue regeneration, wound healing, tissue adhesives, bioprinting, and biosensors.

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Crossref · 10.3390/molecules24163005

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Metadata

Authors
Xu, J., Liu, Y., & Hsu, S.-H.
Venue
Molecules
Publisher
MDPI AG
Published
2019-08-19
Volume
24
Issue
16
Pages
3005
ISSN
1420-3049 (ISSN-L)
OpenAlex
W2967070597
Cited by
559
References
98
FWCI
12.73
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Hydrogels Based on Schiff Base Linkages for Biomedical Applications. https://app.cochat.ai/papers/10.3390/molecules24163005
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Xu, J., Liu, Y., & Hsu, S.-H. (2019). Hydrogels Based on Schiff Base Linkages for Biomedical Applications. Molecules. https://doi.org/10.3390/molecules24163005

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.