Aptamers: A Review of Their Chemical Properties and Modifications for Therapeutic Application

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Characterization of 2′-Fluoro-RNA Aptamers That Bind Preferentially to Disease-associated Conformations of Prion Protein and Inhibit Conversion

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Assembling OX40 Aptamers on a Molecular Scaffold to Create a Receptor-Activating Aptamer

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Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing

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Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein

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Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth

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Immunotherapy of CD30-expressing lymphoma using a highly stable ssDNA aptamer

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Post-SELEX Chemical Optimization of a Trypanosome-Specific RNA Aptamer

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AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

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Aptamer imaging with Cu-64 labeled AS1411: Preliminary assessment in lung cancer

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Transcription yield of fully 2′-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants

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Architecture of high-affinity unnatural-base DNA aptamers toward pharmaceutical applications

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Synthesis and radiolabeling of chelator–RNA aptamer bioconjugates with copper-64 for targeted molecular imaging

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Boron-containing aptamers to ATP

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Pegaptanib for the treatment of age-related macular degeneration

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Cell-Internalization SELEX: Method for Identifying Cell-Internalizing RNA Aptamers for Delivering siRNAs to Target Cells

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DNA aptamer assemblies as fibroblast growth factor mimics and their application in stem cell culture

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Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras

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In Vivo SELEX of an Inhibitory NSCLC-Specific RNA Aptamer from PEGylated RNA Library

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In vitro selection of phosphorothiolated aptamers

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DNA Thioaptamer with Homing Specificity to Lymphoma Bone Marrow Involvement

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Lipids and Lipid Derivatives for RNA Delivery

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Recent advances in quantum dots-based biosensors for antibiotics detection

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Next-Generation Intelligent MXene-Based Electrochemical Aptasensors for Point-of-Care Cancer Diagnostics

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New developments in the biology of fibroblast growth factors

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Nucleic Acid Therapeutics: Successes, Milestones, and Upcoming Innovation

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Generative aptamer discovery using RaptGen

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Exosomes as nanocarriers for brain-targeted delivery of therapeutic nucleic acids: advances and challenges

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Non-canonical DNA structures: Diversity and disease association

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Aptamer-Targeted Photodynamic Platforms for Tumor Therapy

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Drug Metabolism and Pharmacokinetics of Antisense Oligonucleotide Therapeutics: Typical Profiles, Evaluation Approaches, and Points to Consider Compared with Small Molecule Drugs

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Chemistry of Peptide-Oligonucleotide Conjugates: A Review

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G-quadruplex-based aptamers targeting human thrombin: Discovery, chemical modifications and antithrombotic effects

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The Application of Nanomaterials for the Electrochemical Detection of Antibiotics: A Review

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Biomedical Applications of Metal–Organic Frameworks Revisited

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Spatiotemporal delivery of bioactive molecules for wound healing using stimuli-responsive biomaterials

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Photoresponsive Drug Delivery Systems: Challenges and Progress

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RNA Therapeutics - Research and Clinical Advancements

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Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer

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Nanozyme and Stimulated Fluorescent Cu-Based Metal–Organic Frameworks (Cu-MOFs) Functionalized with Engineered Aptamers as a Molecular Recognition Element for Thrombin Detection in the Plasma of COVID-19 Patients

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Cell Surface Engineering Tools for Programming Living Assemblies

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Electrochemical aptasensors for clinical diagnosis. A review of the last five years

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Development and classification of RNA aptamers for therapeutic purposes: an updated review with emphasis on cancer

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Aptasensors Are Conjectured as Promising ALT and AST Diagnostic Tools for the Early Diagnosis of Acute Liver Injury

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Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods

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Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition

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Aptamers and nanobodies as alternatives to antibodies for ligand-targeted drug delivery in cancer

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Computational Frontiers in Aptamer-Based Nanomedicine for Precision Therapeutics: A Comprehensive Review

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Overcoming Challenges in Electrochemical Sensing: Toward Continuous Monitoring

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Organic Electrochemical Transistor Aptasensor for Interleukin-6 Detection

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Overview of the Therapeutic Potential of Aptamers Targeting Coagulation Factors

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Oligonucleotide aptamers for pathogen detection and infectious disease control

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DNA‐Based Dissipative Assembly toward Nanoarchitectonics

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Advances in Design Strategies of Multiplex Electrochemical Aptasensors

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Aptamer-Mediated Nanotheranostics for Cancer Treatment: A Review

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Novel formulations and drug delivery systems to administer biological solids

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Recent progress in the early detection of cancer based on CD44 biomarker; nano-biosensing approaches

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Homobivalent, Trivalent, and Covalent PROTACs: Emerging Strategies for Protein Degradation

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RNA-binding proteins as therapeutic targets in cancer

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Liposome-Based Bioassays

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Synthetic and Biogenic Materials for Oral Delivery of Biologics: From Bench to Bedside

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Cornea‐SELEX for aptamers targeting the surface of eyes and liposomal drug delivery

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Impedimetric ultrasensitive detection of trypsin based on hybrid aptamer-2DMIP using a glassy carbon electrode modified by nickel oxide nanoparticle

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The 20th Anniversary of Pegaptanib (MacugenTM), the First Approved Aptamer Medicine: History, Recent Advances and Future Prospects of Aptamers in Therapy

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Aptamer-based targeted drug delivery and disease therapy in preclinical and clinical applications

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A Non-label Electrochemical Aptasensor Based on Cu Metal–Organic Framework to Measure Aflatoxin B1 in Wheat Flour

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Enhancing non-viral DNA delivery systems: Recent advances in improving efficiency and target specificity

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Electrochemical Aptasensors Based on Hybrid Metal-Organic Frameworks

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An Aptasensor Based on a Flexible Screen-Printed Silver Electrode for the Rapid Detection of Chlorpyrifos

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Recent advances in aptamer-based platforms for cortisol hormone monitoring

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Aptamers: Novel Therapeutics and Potential Role in Neuro-Oncology

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Aptamer-based Theranostics in Oncology: Design Strategies and Limitations

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Truncations and in silico docking to enhance the analytical response of aptamer-based biosensors

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Harnessing synthetic biology for advancing RNA therapeutics and vaccine design

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Decoding aptamer-protein binding kinetics for continuous biosensing using single-molecule techniques

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Cortisol sensing by optical sensors

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Advances in Screening and Development of Therapeutic Aptamers Against Cancer Cells

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Recent advances of cell surface modification based on aptamers

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Growth hormone-releasing hormone and its analogues in health and disease

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Chimeric antigen receptor Treg therapy in transplantation

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Methods to study circRNA-protein interactions

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Aptamer-based approaches in leukemia: a paradigm shift in targeted therapy

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Aptamer-Based Antibacterial and Antiviral Therapy against Infectious Diseases

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Aptamers: precision tools for diagnosing and treating infectious diseases

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Inhibition of thrombin activity by a covalent-binding aptamer and reversal by the complementary strand antidote

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Oligonucleotide-Based Therapies for Renal Diseases

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Sensitive detection of Escherichia coli in diverse foodstuffs by electrochemical aptasensor based on 2D porphyrin-based COF

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Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine

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Triple multivalent aptamers within DNA tetrahedron on reduced graphene oxide electrode: Unlocking enhanced sensitivity and accelerated reactions in electrochemical sensing

Jang, S. J., & Kim, T. H. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116039 · Cited by 26 · see citing works

Effects of Experimental Conditions on the Signaling Fidelity of Impedance-Based Nucleic Acid Sensors

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The eEF1A protein in cancer: Clinical significance, oncogenic mechanisms, and targeted therapeutic strategies

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Aptamer and Oligonucleotide-Based Biosensors for Health Applications

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Diagnostics and Therapeutics in Targeting HER2 Breast Cancer: A Novel Approach

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Uptake mechanisms of cell-internalizing nucleic acid aptamers for applications as pharmacological agents

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Aptamer-Based Strategies to Boost Immunotherapy in TNBC

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Repurposing CRISPR/Cas to Discover SARS‐CoV‐2 Detecting and Neutralizing Aptamers

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Switchable DNA Catalysts for Proximity Labeling at Sites of Protein–Protein Interactions

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Multidimensional applications of prussian blue-based nanoparticles in cancer immunotherapy

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Recent Progress on Highly Selective and Sensitive Electrochemical Aptamer-based Sensors

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Exosome-mediated aptamer S58 reduces fibrosis in a rat glaucoma filtration surgery model

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Aptamer-coated track-etched membranes with a nanostructured silver layer for single virus detection in biological fluids

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Aptamers as target-specific recognition elements in drug delivery

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Picomolar detection of thrombin with fiber-optic ball resonator sensor using optical backscatter reflectometry

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Recent Advances in DNA Nanotechnology for Plasmonic Biosensor Construction

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Unlocking precision in aptamer engineering: a case study of the thrombin binding aptamer illustrates why modification size, quantity, and position matter

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Designing a new dimerized anti human TNF‐α aptamer with blocking activity

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A Novel Electrochemical Aptasensor Based on a New Platform of Samarium Molybdate Flower-like Nanoparticles@Poly(pyrrole) for Non-Invasive Determination of Saliva CORTISOL

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A Two-Dimensional Affinity Capture and Separation Mini-Platform for the Isolation, Enrichment, and Quantification of Biomarkers and Its Potential Use for Liquid Biopsy

Guzman, N. A., & Guzman, D. E. (2020) · Biomedicines · doi:10.3390/biomedicines8080255 · Cited by 22 · see citing works

Relative Nuclease Resistance of a DNA Aptamer Covalently Conjugated to a Target Protein

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Advances in RNA cancer therapeutics: New insight into exosomes as miRNA delivery

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A capacitive laser-induced graphene based aptasensor for SARS-CoV-2 detection in human saliva

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Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology

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APTAMERS AS USEFUL TOOL FOR THERAPEUTIC AND THERANOSTIC APPLICATIONS

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Clinical use and future perspective of aptamers

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Aptamers: a new class of oligonucleotides in the drug discovery pipeline?

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The 20th Anniversary of Pegaptanib (MacugenTM), the First Approved Aptamer Medicine: History, Recent Advances and Future Prospects of Aptamers in Therapy

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Aptamers: Diagnostic and Therapeutic Applications

Fesseha, H. (2020) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2020.28.004672 · Cited by 5 · see citing works