The DOI matches its Crossref record; 169 of the 169 references it cites were found in a registry or an index.
Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents
Open accessAbstract
Recently, deep eutectic solvent (DES) or ionic liquid (IL) analogues have been considered as the newest green solvent, demonstrating the potential to replace harsh volatile organic solvents. DESs are mainly a combination of two compounds: hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD), which have the ability to interact through extensive hydrogen bonds. A thorough understanding of their physicochemical properties is essential, given their successful applications on an industrial scale. The appropriate blend of HBA to HBD can easily fine-tune DES properties for desired applications. In this context, we have reviewed the basic information related to DESs, the two most studied physicochemical properties (density and viscosity), and their performance as a solvent in (i) drug delivery and (ii) extraction of biomolecules. A broader approach of various factors affecting their performance has been considered, giving a detailed picture of the current status of DESs in research and development.
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Cites
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Cited by
Green and Sustainable Solvents of the Future: Deep Eutectic Solvents
Prabhune, A., & Dey, R. (2023) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2023.121676 · Cited by 500
Natural Deep Eutectic Solvents (NaDES): Green Solvents for Pharmaceutical Applications and Beyond
Chevé-Kools, E., Choi, Y. H., Roullier, C., Ruprich-Robert, G., Grougnet, R., Chapeland-Leclerc, F., & Hollmann, F. (2025) · Green Chemistry · doi:10.1039/d4gc06386d · Cited by 156
Katrak, V. K., Patel, N. A., & Ijardar, S. P. (2026) · Critical Reviews in Analytical Chemistry · doi:10.1080/10408347.2025.2486209 · Cited by 16
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Metadata
- Authors
- Ijardar, S. P., Singh, V., & Gardas, R. L.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2022-02-17
- Volume
- 27
- Issue
- 4
- Pages
- 1368
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W4213082258
- Cited by
- 363
- References
- 169
- FWCI
- 11.03
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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