The DOI matches its Crossref record; 107 of the 108 references it cites were found in a registry or an index.
Gut Microbiota and Obesity: A Role for Probiotics
Open accessAbstract
Nowadays, obesity is one of the most prevalent human health problems. Research from the last 30 years has clarified the role of the imbalance between energy intake and expenditure, unhealthy lifestyle, and genetic variability in the development of obesity. More recently, the composition and metabolic functions of gut microbiota have been proposed as being able to affect obesity development. Here, we will report the current knowledge on the definition, composition, and functions of intestinal microbiota. We have performed an extensive review of the literature, searching for the following keywords: metabolism, gut microbiota, dysbiosis, obesity. There is evidence for the association between gut bacteria and obesity both in infancy and in adults. There are several genetic, metabolic, and inflammatory pathophysiological mechanisms involved in the interplay between gut microbes and obesity. Microbial changes in the human gut can be considered a factor involved in obesity development in humans. The modulation of the bacterial strains in the digestive tract can help to reshape the metabolic profile in the human obese host as suggested by several data from animal and human studies. Thus, a deep revision of the evidence pertaining to the use probiotics, prebiotics, and antibiotics in obese patients is conceivable
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“However, Bacteroides sometimes correlate with higher BMI and a Westernized diet [105]”
From The athletic gut microbiota (2020) · cites this paper as [105]
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“therefore, the increased relative abundance observed after the 12-week exercise intervention may be due to its ability to shift substrates compared to other taxa that more reproducibly decline with a high-fat diet (i.e., Bifidobacteria).”
From The athletic gut microbiota (2020) · cites this paper as [105]
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1 retracted
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1 of the 108 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
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Probiotics improve obesity development and modulate gut microbiota in rabbits and their offsprings
Bouaziz, A., Dib, A. L., Monnoye, M., Kadja, L., Espigares, E., & Gérard, P. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107344
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Connecting gut microbiome composition to symptom severity and host genetics in endometriosis
Nardone, G. G., Rosso, L. E., Santin, A., Spedicati, B., Cappellani, S., Concas, M. P., Zito, G., Romano, F., Lorenzo, G. D., Zanotta, N., et al. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1873766
Metadata
- Authors
- Abenavoli, L., Scarpellini, E., Colica, C., Boccuto, L., Salehi, B., Sharifi-Rad, J., Aiello, V., Romano, B., De Lorenzo, A., Izzo, A. A., & Capasso, R.
- Affiliations
- Magna Graecia University (IT)
- Clinical Nutrition Unit, and Internal Medicine Unit, “Madonna del Soccorso” General Hospital, Via Luciano Manara 7, 63074 San Benedetto del Tronto (AP), Italy
- Greenwood Genetic Center (US)
- Bam University of Medical Sciences (IR)
- Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615585, Iran
- University of Naples Federico II (IT)
- Division of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
- Corresponding author
- Abenavoli, Ludovico
- Capasso, Raffaele
- ORCID
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2019-11-07
- Volume
- 11
- Issue
- 11
- Pages
- 2690
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC6893459
- OpenAlex
- W2986976548
- Cited by
- 615
- References
- 108
- Citations by year
- 2026: 42 · 2025: 83 · 2024: 122 · 2023: 111 · 2022: 126 · 2021: 90 · 2020: 38
- FWCI
- 5.61
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- gut microbiota, obesity, probiotics, dysbiosis, prebiotics, antibiotics, energy balance, inflammation, microbial metabolism, infant obesity, obesity pathophysiology
- MeSH terms
- Gastrointestinal Microbiome, Animals, Humans, Obesity, Probiotics, Mice, Rats, Dysbiosis
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