The Effect of Different Postprandial Exercise Types on Glucose Response to Breakfast in Individuals with Type 2 Diabetes
Open accessAbstract
Postprandial exercise represents an important tool for improving the glycemic response to a meal. This study evaluates the effects of the combination and sequence of different exercise types on the postprandial glycemic response in patients with type 2 diabetes. In this repeated-measures crossover study, eight patients with type 2 diabetes performed five experimental conditions in a randomized order: (i) uninterrupted sitting (CON); (ii) 30 min of moderate intensity aerobic exercise (walking) (A); (iii) 30 min of combined aerobic and resistance exercise (AR); (iv) 30 min of combined resistance and aerobic exercise (RA); and (v) 15 min of resistance exercise (R). All the exercise sessions started 30 min after the beginning of a standardized breakfast. All the exercise conditions showed a significant attenuation of the post-meal glycemic excursion (P < 0.003) and the glucose incremental area under the curve at 0–120 min (P < 0.028) and 0–180 min (P < 0.048) compared with CON. A greater reduction in the glycemic peak was observed in A and AR compared to RA (P < 0.02). All the exercise types improved the post-meal glycemic response in patients with type 2 diabetes, with greater benefits when walking was performed alone or before resistance exercise.
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Postprandial hyperglycaemia and insulin excursions are stronger predictors of cardiometabolic risk than fasting hyperglycaemia, particularly in individuals with insulin resistance or excess adiposity.
“evidence suggests that postprandial hyperglycaemia and insulin excursions are stronger predictors of cardiometabolic risk than fasting hyperglycaemia, particularly in individuals with insulin resistance or excess adiposity (Bellini et al., 2021).”
From Acute systemic and energy metabolism responses to velocity-based resistance training following an oral glucose load in individuals with excess body weight (2026) · cites this paper as Bellini et al., 2021
The Introduction says postprandial hyperglycemia and high glucose excursions are better predictors of cardiometabolic disorders than chronic fasting hyperglycemia in patients with type 2 diabetes. It does not make that comparison for insulin excursions or specifically for people with insulin resistance or excess adiposity. (LLM, conf=0.90)
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- Authors
- Bellini, A., Nicolò, A., Bulzomì, R., Bazzucchi, I., & Sacchetti, M.
- Affiliations
- Foro Italico University of Rome (IT)
- ASL Roma (IT)
- Corresponding author
- Sacchetti, Massimo
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2021-04-24
- Volume
- 13
- Issue
- 5
- Pages
- 1440
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC8145872
- OpenAlex
- W3158730051
- Cited by
- 25
- References
- 32
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 6 · 2023: 4 · 2022: 6 · 2021: 1
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- University of Rome Foro Italico (CDR2.BANDO2017SM)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- postprandial exercise, type 2 diabetes, postprandial glycemic response, breakfast, aerobic exercise, resistance training, walking, exercise sequence, glycemic excursions
- MeSH terms
- Diabetes Mellitus, Type 2, Female, Glucose, Humans, Male, Middle Aged, Exercise, Walking, Cross-Over Studies, Postprandial Period, Breakfast
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