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Cited by 86Diabetes Management and ResearchDiabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Continuous glucose monitoring in a healthy population: understanding the post-prandial glycemic response in individuals without diabetes mellitus

Open access
Jarvis, Paul R.E., Cardin, Jessica L., Nisevich-Bede, Pamela M., McCarter, James P.·2023·Metabolism
DOI 10.1016/j.metabol.2023.155640
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Abstract

Continuous glucose monitoring has become a common adjunct in the management of Diabetes Mellitus. However, there has been a recent trend among individuals without diabetes using these devices as a means of monitoring their health. The increased visibility of glucose data has allowed users to study the effect lifestyle has upon post-prandial glucose levels. Although post-prandial hyperglycemia is well understood in the setting of diabetes, its impact in individuals without diabetes is less well defined. This article reviews the factors which contribute to post-prandial hyperglycemia in individuals without diabetes and how the data obtained from continuous glucose monitoring can be used to improve an individual's metabolic health.

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Crossref · 10.1016/j.metabol.2023.155640

Cites

115 of 115 references verified0 citation errors · 0 not checkable

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  • Fasting glucose assesses carbohydrate metabolism and may indicate hypoglycemia, insulin resistance or diabetes.

    “Fasting Glucose (70-100 mg/dL) Assesses carbohydrate metabolism and may indicate hypoglycemia, insulin resistance or diabetes.[22]”

    From The Seven Methods for the Evaluation of Nutritional Status—ABCDEFG: Narrative Review (2026) · cites this paper as [22]

    Section 2 (Post-prandial Hyperglycemia; page unavailable) links poorer fasting blood-glucose control with insulin resistance and reports lower fasting glucose among people with normal glucose tolerance. But the paper does not present 70–100 mg/dL as a fasting range or state that fasting glucose indicates hypoglycemia or diagnoses diabetes; Section 3 describes hypoglycemia specifically after meals. (LLM, conf=0.84)

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  • Glycosylated hemoglobin indicates glycemic control over the past 3 months.

    “Glycosylated hemoglobin (<5.7% normal, >6.5% diabetes) Indicates glycemic control over the past 3 months.[22]”

    From The Seven Methods for the Evaluation of Nutritional Status—ABCDEFG: Narrative Review (2026) · cites this paper as [22]

    Section 5, “Long-Term Consequence of Post-Prandial Hyperglycemia” (page unavailable), says HbA1c is a time-average measure of glycemia. It does not specify a three-month period or give the 5.7% and 6.5% thresholds in the citing sentence. (LLM, conf=0.85)

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Cites

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1 of the 116 references couldn’t be matched to a known paper.

Research works printed but not linked: 6

  1. Giugliano D, Ceriello A, Esposito K. Gluce metabolism and hyperglycemia. Am J Clin Nutr. 2008 Jan;87(1):217S-222S.
  2. Armstrong M, Haldane F, Avery PJ, Mitcheson J, Stewart MW, Turnbull DM, Walker M. Relationship between insulin sensitivity and insulin receptor substrate-1 mutations in non-diabetic relatives of NIDDM families. Diabet Med. 1996 Apr;13(4):341-5.
  3. Richter, E. A. (2021). Is GLUT4 translocation the answer to exercise-stimulated muscle glucose uptake? American Journal of Physiology. Endocrinology and Metabolism, 320, E240-E243.
  4. Bornemisza P, Suciu I. Effect of cigarette smoking on the blood glucose level in 17ormal and diabetics. Med Interne. 1980; 18:353-6.
  5. Solomon TPJ, Eves FF, Laye MJ. Targeting Postprandial Hyperglycemia With Physical Activity May Reduce Cardiovascular Disease Risk. But What Should We Do, and When Is the Right Time to Move? Front. Cardiovasc. Med. 2018 ;5:99.
  6. J o u r n a l P r e -p r o o f Journal Pre-proof Graphical abstract J o u r n a l P r e -p r o o

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Authors
Jarvis, P. R. E., Cardin, J. L., Nisevich-Bede, P. M., & McCarter, J. P.
Affiliations
  • Abbott (United States) (US)
  • Washington University in St. Louis (US)
Corresponding author
  • Jarvis, Paul R.E.
  • Cardin, Jessica L.
  • McCarter, James P.
ORCID
Venue
Metabolism
Publisher
Elsevier BV
Published
2023-09
Volume
146
Pages
155640
ISSN
0026-0495 (ISSN-L)
DOI
10.1016/j.metabol.2023.155640
OpenAlex
W4381930651
Cited by
86
References
116
Citations by year
2026: 38 · 2025: 35 · 2024: 13
FWCI
3.10
Type
journal article
Language
en
Open access
Licence
Locations
  • Metabolism (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • OSF Preprints (OSF Preprints) (submittedVersion, public-domain)
  • OSF Preprints (OSF Preprints) (submittedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords
continuous glucose monitoring, postprandial glycemic response, postprandial hyperglycemia, non-diabetic individuals, lifestyle factors, metabolic health, healthy population
MeSH terms
Blood Glucose, Diabetes Mellitus, Diabetes Mellitus, Type 1, Humans, Hyperglycemia, Blood Glucose Self-Monitoring, Postprandial Period

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