The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.
Effects and Mechanisms of Probiotics, Prebiotics, Synbiotics, and Postbiotics on Metabolic Diseases Targeting Gut Microbiota: A Narrative Review
Open accessAbstract
Metabolic diseases are serious threats to public health and related to gut microbiota. Probiotics, prebiotics, synbiotics, and postbiotics (PPSP) are powerful regulators of gut microbiota, thus possessing prospects for preventing metabolic diseases. Therefore, the effects and mechanisms of PPSP on metabolic diseases targeting gut microbiota are worth discussing and clarifying. Generally, PPSP benefit metabolic diseases management, especially obesity and type 2 diabetes mellitus. The underlying gut microbial-related mechanisms are mainly the modulation of gut microbiota composition, regulation of gut microbial metabolites, and improvement of intestinal barrier function. Moreover, clinical trials showed the benefits of PPSP on patients with metabolic diseases, while the clinical strategies for gestational diabetes mellitus, optimal formula of synbiotics and health benefits of postbiotics need further study. This review fully summarizes the relationship between probiotics, prebiotics, synbiotics, postbiotics, and metabolic diseases, presents promising results and the one in dispute, and especially attention is paid to illustrates potential mechanisms and clinical effects, which could contribute to the next research and development of PPSP.
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1 retracted
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Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes
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Self-citationRoy, S., & Dhaneshwar, S. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i14.2078 · Cited by 334
Guo, M., Liu, H., Yu, Y., Zhu, X., Xie, H., Wei, C., Mei, C., Shi, Y., Zhou, N., Qin, K., et al. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2190304 · Cited by 269
Probiotic Functions in Fermented Foods: Anti-Viral, Immunomodulatory, and Anti-Cancer Benefits
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Metadata
- Authors
- Li, H.-Y., Zhou, D.-D., Gan, R.-Y., Huang, S.-Y., Zhao, C.-N., Shang, A., Xu, X.-Y., & Li, H.-B.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2021-09-15
- Volume
- 13
- Issue
- 9
- Pages
- 3211
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W3200907339
- Cited by
- 490
- References
- 143
- FWCI
- 8.86
- Type
- journal article
- Language
- en
- Open access
- gold
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- Li, H.-Y., Zhou, D.-D., Gan, R.-Y., Huang, S.-Y., Zhao, C.-N., Shang, A., Xu, X.-Y., & Li, H.-B. (2021). Effects and Mechanisms of Probiotics, Prebiotics, Synbiotics, and Postbiotics on Metabolic Diseases Targeting Gut Microbiota: A Narrative Review. Nutrients. https://doi.org/10.3390/nu13093211
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