The DOI matches its Crossref record; 50 of the 51 references it cites were found in a registry or an index, and 1 are not checked yet.
Basal Serum Diamine Oxidase Levels as a Biomarker of Histamine Intolerance: A Retrospective Cohort Study
Open accessAbstract
Background: Histamine Intolerance (HIT) is a multifaceted pseudoallergic disorder possibly due to defective histamine metabolism. Diamine oxidase (DAO) contributes to histamine degradation and can be measured in the serum. The role of DAO measurement in the diagnostic work-up of HIT still remains unclear, and conflicting results have been reported in the literature. Therefore, we aimed to evaluate the possible clinical usefulness and consistency of DAO value ranges as provided by the assay manufacturer and verify whether they could predict the response to treatment. Methods: We retrospectively analyzed 192 outpatients with HIT symptoms and measured serum DAO values at baseline. Patients were prescribed either with low-histamine diet and/or enzymatic supplementation according to symptom severity and re-evaluated six to eight months later. Patients were stratified into three groups according to DAO levels: <3 U/mL, 3–10 U/mL, and >10 U/mL. HIT severity was assessed on a scale of 1 to 5 before and after treatment. Results: A total of 146 patients completed the study. Gastrointestinal and cutaneous symptoms, often associated with headache, were more frequent in subjects with DAO < 10 U/mL. Symptom severity and DAO ranges were correlated. Patients with intermediate DAO levels (3–10 U/mL) showed a more complex clinical phenotype but also a more significant improvement in symptom severity (score reduction 50%, interquartile range (IQR) = 33–60%) when compared to patients with low DAO (40%, IQR = 20–60%; p = 0.045) or high DAO (33%, IQR = 0–50%; p < 0.001). Complex clinical phenotypes were also more frequent in patients with intermediate DAO levels. Conclusions: HIT is characterized by typical symptoms and low levels of DAO activity. Symptom severity was associated with the degree of DAO deficiency. Patients with DAO values between 3 and 10 U/mL show the best response to treatment (low-histamine diet and/or DAO supplementation). DAO value could arguably be considered as a predictor of clinical response to treatment. Prospective studies are needed to confirm these data.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Most patients with a high probability of HIT had DAO concentrations below 10 U/mL.
“Most patients with a “high probability of HIT” had DAO concentrations below 10 U/mL, similar to those reported previously [ 16 ].”
From Evaluation of Serum Diamine Oxidase as a Diagnostic Test for Histamine Intolerance (2023) · cites this paper as [16]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
FRANCIS, C. Y., MORRIS, J., & WHORWELL, P. J. (1997) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1997.142318000.x · Cited by 1,708
The epidemiology of irritable bowel syndrome
Card, T., Canavan, C., & West, J. (2014) · Clinical Epidemiology · doi:10.2147/clep.s40245 · Cited by 889
Histamine and histamine intolerance
Maintz, L., & Novak, N. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.5.1185 · Cited by 874
Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors
Jutel, M., Watanabe, T., Klunker, S., Akdiş, M., Thomet, O. A. R., Małolepszy, J., Zak-Nejmark, T., Koga, R., Kobayashi, T., Blaser, K., et al. (2001) · Nature · doi:10.1038/35096564 · Cited by 583
Review article: the diagnosis and management of food allergy and food intolerances
Turnbull, J., Adams, H. N., & Gorard, S. A. C. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12984 · Cited by 309
Histamine Intolerance: The Current State of the Art
Comas-Basté, O., Sánchez-Pérez, S., Veciana-Nogués, M. T., Latorre-Moratalla, M., & Vidal-Carou, M. D. C. (2020) · Biomolecules · doi:10.3390/biom10081181 · Cited by 246
Irritable bowel syndrome, the microbiota and the gut-brain axis
Raskov, H., Burcharth, J., Pommergaard, H.-C., & Rosenberg, J. (2016) · Gut Microbes · doi:10.1080/19490976.2016.1218585 · Cited by 243
Histamine, histamine intoxication and intolerance
Kováčová, E., Buday, T., Gavliakova, S., & Plevková, J. (2015) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2015.05.001 · Cited by 181
Epidemiology of Irritable Bowel Syndrome
Choung, R. S., & Saito, Y. A. (2014) · Wiley eBooks · doi:10.1002/9781118727072.ch20 · Cited by 163
Tuck, C. J., Biesiekierski, J. R., Schmid‐Grendelmeier, P., & Pohl, D. (2019) · Nutrients · doi:10.3390/nu11071684 · Cited by 156
Sattler, J., Häfner, D., Klotter, H. J., Lorenz, W., & Wagner, P. K. (1988) · Inflammation Research · doi:10.1007/bf02142588 · Cited by 132
Wantke, F., Götz, M., & Jarisch, R. (1993) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1993.tb00287.x · Cited by 122
Histamine Intolerance—The More We Know the Less We Know. A Review
Hrubiško, M., Danis, R., Huorka, M., & Wawruch, M. (2021) · Nutrients · doi:10.3390/nu13072228 · Cited by 120
Beneduce, L., Romano, A., Capozzi, V., Lucas, P., Barnavon, L., Bach, B., Vuchot, P., Grieco, F., & Spano, G. (2010) · Annals of Microbiology · doi:10.1007/s13213-010-0094-4 · Cited by 106
Wöhrl, S., Hemmer, W., Focke, M., Rappersberger, K., & Jarisch, R. (2004) · PubMed · Cited by 100
Serum diamine oxidase activity in patients with histamine intolerance.
Manzotti, G., Breda, D., Di Gioacchino, M., & Burastero, S. (2016) · International Journal of Immunopathology and Pharmacology · doi:10.1177/0394632015617170 · Cited by 98
Self-citationEvaluation of symptoms and symptom combinations in histamine intolerance
Schnedl, W. J., Lackner, S., Enko, D., Schenk, M., Holasek, S. J., & Mangge, H. (2019) · Intestinal Research · doi:10.5217/ir.2018.00152 · Cited by 95
Histamine Intolerance Originates in the Gut
Schnedl, W. J., & Enko, D. (2021) · Nutrients · doi:10.3390/nu13041262 · Cited by 95
Food Intolerance: The Role of Histamine
Shulpekova, Y. O., Nechaev, V. M., Popova, I. R., Deeva, Т. A., Kopylov, A. T., Malsagova, K. A., Kaysheva, A. L., & Ivashkin, V. T. (2021) · Nutrients · doi:10.3390/nu13093207 · Cited by 88
Diamine oxidase supplementation improves symptoms in patients with histamine intolerance
Schnedl, W. J., Schenk, M., Lackner, S., Enko, D., Mangge, H., & Forster, F. (2019) · Food Science and Biotechnology · doi:10.1007/s10068-019-00627-3 · Cited by 86
Maintz, L., Yu, C., Rodríguez, E., Baurecht, H., Bieber, T. R. M., Illig, T., Weidinger, S., & Novak, N. (2011) · Allergy · doi:10.1111/j.1398-9995.2011.02548.x · Cited by 84
Serum diamine oxidase activity as a diagnostic test for histamine intolerance
Mušič, E., Korošec, P., Šilar, M., Adamič, K., Košnik, M., & Rijavec, M. (2013) · Wiener klinische Wochenschrift · doi:10.1007/s00508-013-0354-y · Cited by 84
The Role of Bacteria, Probiotics and Diet in Irritable Bowel Syndrome
Harper, A. J., Naghibi, M., & Garcha, D. S. (2018) · Foods · doi:10.3390/foods7020013 · Cited by 82
Komericki, P., Klein, G., Reider, N., Hawranek, T., Strimitzer, T., Lang, R., Kranzelbinder, B., & Aberer, W. (2010) · Wiener klinische Wochenschrift · doi:10.1007/s00508-010-1506-y · Cited by 79
Evidence for a reduced histamine degradation capacity in a subgroup of patients with atopic eczema
Maintz, L., Benfadal, S., Allam, J., Hagemann, T., Fimmers, R., & Novak, N. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.11.041 · Cited by 79
Sattler, J., & Lorenz, W. (1990) · Springer eBooks · doi:10.1007/978-3-7091-9113-2_39 · Cited by 70
Microbial patterns in patients with histamine intolerance.
Schink, M., Konturek, P. C., Tietz, E., Dieterich, W., Pinzer, T. C., Wirtz, S. J., Neurath, M. F., & Zopf, Y. (2018) · PubMed · doi:10.26402/jpp.2018.4.09 · Cited by 70
A Histamine-Free Diet Is Helpful for Treatment of Adult Patients with Chronic Spontaneous Urticaria
Son, J. H., Chung, B. Y., Kim, H. O., & Park, C. W. (2018) · Annals of Dermatology · doi:10.5021/ad.2018.30.2.164 · Cited by 60
Vidal‐Carou, M. C., Codony-Salcedo, R., & Mariné‐Font, A. (1990) · Food Chemistry · doi:10.1016/0308-8146(90)90035-3 · Cited by 56
Esposito, F., Montuori, P., Schettino, M., Velotto, S., Stasi, T., Romano, R., & Cirillo, T. (2019) · Molecules · doi:10.3390/molecules24193629 · Cited by 53
Yacoub, M., Ramirez, G. A., Berti, A., Mercurio, G., Breda, D., Saporiti, N., Burastero, S. E., Dagna, L., & Colombo, G. (2018) · International Archives of Allergy and Immunology · doi:10.1159/000488142 · Cited by 49
Self-citationLackner, S., Malcher, V., Enko, D., Mangge, H., Holasek, S. J., & Schnedl, W. J. (2018) · European Journal of Clinical Nutrition · doi:10.1038/s41430-018-0260-5 · Cited by 48
Considering histamine in functional gastrointestinal disorders
Schnedl, W. J., & Enko, D. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1791049 · Cited by 47
Pinzer, T. C., Tietz, E., Waldmann, E., Schink, M., Neurath, M. F., & Zopf, Y. (2017) · Allergy · doi:10.1111/all.13361 · Cited by 45
Schirmer, B., & Neumann, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116116 · Cited by 39
Evaluation of porcine diamine oxidase for the conversion of histamine in food‐relevant amounts
Kettner, L., Seitl, I., & Fischer, L. (2020) · Journal of Food Science · doi:10.1111/1750-3841.15069 · Cited by 38
Reese, I., Ballmer-Weber, B. K., Beyer, K., Dölle-Bierke, S., Kleine‐Tebbe, J., Klimek, L., Lämmel, S., Lepp, U. S., Saloga, J., Schäfer, C., et al. (2021) · Allergologie select · doi:10.5414/alx02269e · Cited by 38
Diet and Chronic Urticaria: Dietary Modification as a Treatment Strategy
Jaros, J., Shi, V. Y., & Katta, R. (2019) · Dermatology Practical & Conceptual · doi:10.5826/dpc.1001a04 · Cited by 36
Living with Gluten and Other Food Intolerances: Self-Reported Diagnoses and Management
Araya, M., Bascuñán, K. A., Alarcón-Sajarópulos, D., Cabrera‐Chávez, F., Amaya Oyarzún, A., Fernández, A., & Ontiveros, N. (2020) · Nutrients · doi:10.3390/nu12061892 · Cited by 34
Schnedl, W. J., Lackner, S., Enko, D., Schenk, M., Mangge, H., & Holasek, S. J. (2017) · Inflammation Research · doi:10.1007/s00011-017-1117-4 · Cited by 30
Alonso, N., Fernández, N., Notcovich, C., Monczor, F., Simaan, M., Baldi, A., Gutkind, J. S., Davio, C. A., & Shayo, C. (2013) · Molecular Pharmacology · doi:10.1124/mol.112.083394 · Cited by 29
Diaminoxidase keine diagnostische Hilfe bei Histaminintoleranz
Kofler, H., Aberer, W., Deibl, M., Hawranek, T., Klein, G., Reider, N., & Fellner, N. (2009) · Allergologie · doi:10.5414/alp32105 · Cited by 27
Treatment of irritable bowel syndrome
Basnayake, C. (2018) · Australian Prescriber · doi:10.18773/austprescr.2018.044 · Cited by 25
Griauzdaitė, K., Maselis, K., Žvirblienė, A., Vaitkus, A., Jančiauskas, D., Baleišienė, I. B. , Kupčinskas, L., & Rastenytė, D. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.109738 · Cited by 25
The implications of histamine metabolism and signaling in renal function
Sudarikova, A. V., Fomin, M. V., Yankelevich, I. A., & Ilatovskaya, D. V. (2021) · Physiological Reports · doi:10.14814/phy2.14845 · Cited by 23
Serum diamine oxidase activity is associated with lactose malabsorption phenotypic variation
Enko, D., Kriegshäuser, G., Halwachs‐Baumann, G., Mangge, H., & Schnedl, W. J. (2016) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.08.019 · Cited by 22
Schnedl, W. J., Mangge, H., Schenk, M., & Enko, D. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110404 · Cited by 22
Gastrointestinal Food Allergies and Intolerances
Hon, E. C., & Gupta, S. K. (2021) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2020.10.006 · Cited by 20
Intolérance à l’histamine ou fausses allergies alimentaires de mécanisme histaminique
Lefèvre, S., Astier, C., & Kanny, G. (2016) · Revue française d'allergologie · doi:10.1016/j.reval.2016.10.004 · Cited by 19
Mayer, I., Mißbichler, A., Wantke, F., Focke, M., Reichl, H., Winter, M., & Jarisch, R. (2005) · Allergologie · doi:10.5414/alp28001 · Cited by 14
Diamine oxidase determination in serum
Schnoor, H. J., Mosbech, H., Skov, P. S., Poulsen, L. K., & Jensen, B. M. (2013) · Allergo Journal · doi:10.1007/s15007-013-0063-x · Cited by 8
Flagged first, then by citations
Research works printed but not linked: 1
- Astier, 2017, Histamine intolerance or false food allergy with histamine mechanism, Rev. Fr. D’allergologie, 57, 24
Cited by
Sorted by citations
Obianwuna, U. E., Chang, X., Oleforuh-Okoleh, V. U., Onu, P. N., Zhang, H., Qiu, K., & Wu, S. (2024) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-024-01101-9 · Cited by 213
Advances in the Clinical Application of Histamine and Diamine Oxidase (DAO) Activity: A Review
Tan, Z., Ou, Y., Cai, W., Zheng, Y., Li, H., Mao, Y., Zhou, S., & Tu, J. (2022) · Catalysts · doi:10.3390/catal13010048 · Cited by 40
van Odijk, J., Weisheit, A., Arvidsson, M., Miron, N., Nwaru, B. I., & Ekerljung, L. (2023) · Nutrients · doi:10.3390/nu15132887 · Cited by 27
Evaluation of Serum Diamine Oxidase as a Diagnostic Test for Histamine Intolerance
Arih, K., Đorđević, N., Košnik, M., & Rijavec, M. (2023) · Nutrients · doi:10.3390/nu15194246 · Cited by 20
Rentzos, G., Weisheit, A., Ekerljung, L., & van Odijk, J. (2024) · European Journal of Clinical Nutrition · doi:10.1038/s41430-024-01448-2 · Cited by 17
Duelo, A., Comas-Basté, O., Sánchez-Pérez, S., Veciana-Nogués, M. T., Ruiz-Casares, E., Vidal‐Carou, M. C., & Latorre‐Moratalla, M. L. (2024) · Nutrients · doi:10.3390/nu16081142 · Cited by 12
Mechanisms and implications of histamine-induced reactions and complications
Al‐Maamari, A., Sultan, M., Ding, S., Yuxin, D., Wang, M.-Y., & Su, S. (2025) · Allergologia et Immunopathologia · doi:10.15586/aei.v53i3.1272 · Cited by 11
Costa-Catala, J., Pellicer-Roca, S., Iduriaga-Platero, I., Sánchez-Pérez, S., Veciana-Nogués, M. T., Latorre‐Moratalla, M. L., Vidal‐Carou, M. C., & Comas-Basté, O. (2024) · Applied Food Research · doi:10.1016/j.afres.2024.100592 · Cited by 10
A personalized management approach in disorders of the irritable bowel syndrome spectrum
Schnedl, W. J., Michaelis, S., Mangge, H., & Enko, D. (2023) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2023.06.028 · Cited by 11
Marin, E. F., Marcolin, L. C., Melero, L. M., Tintoré, M., & Porres, M. B. (2025) · Genes · doi:10.3390/genes16020141 · Cited by 8
Tobajas, Y., Alemany-Fornés, M., Samarra, I., Romero‐Giménez, J., Tintoré, M., del Pino, A., Canela-Canela, N., Bas-Prior, J. M. D., Ortega-Olivé, N., de Lecea, C., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12237502 · Cited by 8
Costa-Catala, J., Kettner, L., Latorre‐Moratalla, M. L., Vidal‐Carou, M. C., Comas-Basté, O., & Fischer, L. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107771 · Cited by 7
Diamine Oxidase Activity Deficit and Idiopathic Rhinitis: A New Subgroup of Non-Allergic Rhinitis?
Mayo‐Yáñez, M., Díaz-Díaz, A., Calvo‐Henríquez, C., Lechien, J. R., Vaira, L. A., & Figueroa, A. (2023) · Life · doi:10.3390/life13010240 · Cited by 7
Alemany-Fornés, M., Bori, J., Muguerza, B., & Suárez, M. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147130 · Cited by 6
Cooke, Z., Lynam, K., Tuck, C. J., & Trakman, G. (2024) · Clinical & Experimental Allergy · doi:10.1111/cea.14561 · Cited by 6
Matysiak, J. (2022) · Journal of Medical Science · doi:10.20883/medical.e727 · Cited by 5
Schnedl, W. J., Schenk, M., Michaelis, S., Enko, D., & Mangge, H. (2023) · Children · doi:10.3390/children10091444 · Cited by 4
Duelo, A., Sánchez-Pérez, S., Ruiz-León, A. M., Casanovas-Garriga, F., Pellicer-Roca, S., Iduriaga-Platero, I., Costa-Catala, J., Veciana-Nogués, M. T., Fernández‐Solà, J., Muñoz‐Cano, R., et al. (2024) · Nutrients · doi:10.3390/nu17010029 · Cited by 4
Guidelines for the diagnosis and management of histamine intolerance
Buczyłko, K., Bartnicka, A., Kruszewski, J., Plata‐Nazar, K., Piwowarek, K. Ł., Kupczyk, M., Gawlik, R., Lebensztejn, D. M., Bartuzi, Z., Mazela, J. L., et al. (2023) · Alergologia Polska - Polish Journal of Allergology · doi:10.5114/pja.2023.131553 · Cited by 4
Histamine intolerance and irritable bowel syndrome
Golubeva, Y. A., Sheptulina, A. F., & Drapkina, O. M. (2023) · Russian Journal of Preventive Medicine · doi:10.17116/profmed202326061130 · Cited by 3
Usefulness of DAO biomarker in difficult allergy. Consideration based on own typical cases
Buczyłko, K. (2022) · Alergologia Polska - Polish Journal of Allergology · doi:10.5114/pja.2022.122003 · Cited by 3
Cui, Y., Zhang, M., Wang, H., Yu, T., Zhang, A., Lin, G., Guo, Y., & Wu, Y. (2024) · Metabolites · doi:10.3390/metabo14090494 · Cited by 3
Costa-Catala, J., Iduriaga-Platero, I., Bori, J., Vidal‐Carou, M. C., Latorre‐Moratalla, M. L., & Comas-Basté, O. (2025) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2025.102104 · Cited by 3
Duelo, A., Sánchez-Pérez, S., Pellicer-Roca, S., Sánchez-Buxens, S., Comas-Basté, O., Latorre‐Moratalla, M. L., & Vidal‐Carou, M. C. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14134573 · Cited by 2
Serum Immunometabolic Biomarkers Reveal Distinct Phenotypes in Chronic Urticaria
Duman, N., Müftüoğlu, C., Tahhan, B., Coşkun, T., Ece, D., Mert, U., Özkal, S., & Caner, A. (2026) · Diagnostics · doi:10.3390/diagnostics16081148 · Cited by 3
Cooke, Z., Lynam, K., Barrett, J. S., Biesiekierski, J. R., Trakman, G., & Tuck, C. J. (2025) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.70134 · Cited by 2
Safety Considerations for Natural Products Commonly Used By Patients with Allergic Disease
Soffer, G. K., Shroff, P., & Horwitz, R. (2022) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2022.09.025 · Cited by 2
Is DAO in serum affected by food challenge with a histamine-rich meal?
van Odijk, J., & Rentzos, G. (2023) · Journal of Allergy and Clinical Immunology Global · doi:10.1016/j.jacig.2023.100097 · Cited by 2
Tobajas, Y., Alemany-Fornés, M., Samarra, I., Romero‐Giménez, J., Castellana, J. C., Tintoré, M., del Pino, A., Canela-Canela, N., Bas-Prior, J. M. D., Ortega-Olivé, N., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13030792 · Cited by 2
Fuchs, M. (2024) · Medicína pro praxi · doi:10.36290/med.2024.002 · Cited by 1
Histamin İntoleransına Güncel Bakış
Öztekin, Y. (2024) · İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi · doi:10.38079/igusabder.1377431 · Cited by 1
Gharote, H. P., Panchbhai, A. S., & Joshi, D. (2025) · BMC Oral Health · doi:10.1186/s12903-025-05772-2 · Cited by 1
Effects of Germination Parts of Seed Legumes on Histamine Levels in Rats
Ibrahim, I. M. A., El-Dreny, E. G., & Shaheen, M. M. (2022) · Food science and quality management · doi:10.7176/fsqm/116-05
van Odijk, J., Weisheit, A., Ekerljung, L., & Rentzos, G. (2023) · Research Square · doi:10.21203/rs.3.rs-3419643/v1
Validation of New Micro-spectrophotometric Method to Determine Diamine Oxidase Activity in Serum
Sözmen, E. Y., & Sözmen, A. B. (2024) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-024-01253-5
Moran, J., & Moles, G. (2026) · World Journal of Food Science and Technology · doi:10.11648/j.wjfst.20261001.13
Nahrungsmittelunverträglichkeiten
Theobald, S. (2026) · Springer eBooks · doi:10.1007/978-3-662-69828-0_24
Sai, H., Ren, J., Ma, X., Yang, K., Bai, C., Liu, M., Zhao, F., Chen, H., & Li, X. (2026) · BMC Geriatrics · doi:10.1186/s12877-026-07607-3
Histaminergic modulation as a hidden determinant of psychopharmacological clinical response
Alaili, M. K. A. (2026) · Medical Hypotheses · doi:10.1016/j.mehy.2026.111984
Diamine Oxidase and Gastrointestinal Diseases
Żybul, P., Przybyłkowski, A. M., Wojas, O., & Samolinski, B. K. (2026) · Biomolecules · doi:10.3390/biom16081136 · Cited by 1
Garrido, H. G., Dileone, M., Conty, J. L. M., Lopez, B. P., Cano, A. M., Jimenez, J. J. B., Pinedo, F. C., Fernández, M. Z., Sanchez, L. D. D., Pizarro, S. S. J., et al. (2026) · Neurological Sciences and Neurophysiology · doi:10.4103/nsn.nsn_15_26
Metadata
- Authors
- Cucca, V., Ramirez, G. A., Pignatti, P., Asperti, C., Russo, M., Della-Torre, E., Breda, D., Burastero, S. E., Dagna, L., & Yacoub, M.-R.
- Affiliations
- Vita-Salute San Raffaele University (IT)
- Istituti Clinici Scientifici Maugeri (IT)
- Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, 20132 Milan, Italy
- IRCCS Ospedale San Raffaele (IT)
- Corresponding author
- Yacoub, Mona-Rita
- ORCID
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2022-04-05
- Volume
- 14
- Issue
- 7
- Pages
- 1513
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC9003468
- OpenAlex
- W4223477378
- Cited by
- 41
- References
- 50
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 11 · 2023: 10 · 2022: 5
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion, cc-by)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Mast cells and histamine
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- histamine intolerance, diamine oxidase, biomarkers, histamine metabolism, low-histamine diet, treatment response prediction, symptom severity, clinical phenotype, headache, gastrointestinal symptoms, cutaneous manifestations
- MeSH terms
- Headache, Amine Oxidase (Copper-Containing), Histamine, Humans, Retrospective Studies, Biomarkers
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
