The DOI matches its Crossref record; 97 of the 100 references it cites were found in a registry or an index.
Vitamin B12 in Health and Disease
Open accessAbstract
Vitamin B(12) is essential for DNA synthesis and for cellular energy production.This review aims to outline the metabolism of vitamin B(12), and to evaluate the causes and consequences of sub-clinical vitamin B(12) deficiency. Vitamin B(12) deficiency is common, mainly due to limited dietary intake of animal foods or malabsorption of the vitamin. Vegetarians are at risk of vitamin B(12) deficiency as are other groups with low intakes of animal foods or those with restrictive dietary patterns. Malabsorption of vitamin B(12) is most commonly seen in the elderly, secondary to gastric achlorhydria. The symptoms of sub-clinical deficiency are subtle and often not recognized. The long-term consequences of sub-clinical deficiency are not fully known but may include adverse effects on pregnancy outcomes, vascular, cognitive, bone and eye health.
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“Cobalamin (vitamin B12) deficiency induces neurological dysfunction, including myelopathy, neuropathy and neuropsychiatric abnormalities. Such neurological damage has been reported in 20–30% of cases of vitamin B12 deficiency [147], and can even occur before serum vitamin B12 concentrations reach a level that would be considered deficient by standard criteria.”
From Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence (2020) · cites this paper as [147]
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3 of the 100 references couldn’t be matched to a known paper.
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Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas
Hu, Y., Wu, Q., Ma, S., Ma, T., Shan, L., Wang, X., Nie, Y., Ning, Z., Li, Y., Xiu, Y., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1613870114 · Cited by 263
Metadata
- Authors
- O’Leary, F., & Samman, S.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Samman, Samir
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2010-03-05
- Volume
- 2
- Issue
- 3
- Pages
- 299-316
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC3257642
- OpenAlex
- W2165998744
- Cited by
- 524
- References
- 100
- Citations by year
- 2026: 91 · 2025: 71 · 2024: 56 · 2023: 61 · 2022: 45 · 2021: 42 · 2020: 26 · 2019: 33 · 2018: 20 · 2017: 16 · 2016: 16 · 2015: 10 · 2014: 14 · 2013: 11 · 2012: 6
- FWCI
- 0.85
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Porphyrin Metabolism and Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- vitamin B12, vitamin B12 metabolism, dietary intake, malabsorption, achlorhydria, vegetarians, restrictive diets, pregnancy outcomes, cognitive health, bone health, eye health, vascular health
- MeSH terms
- Absorption, Cardiovascular Diseases, Cognition Disorders, Female, Food, Humans, Male, Neural Tube Defects, Nutritional Requirements, Osteoporosis, Pregnancy, Pregnancy Complications, Vitamin B 12, Vitamin B 12 Deficiency, Biomarkers
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