The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Extracts, Anthocyanins and Procyanidins from Aronia melanocarpa as Radical Scavengers and Enzyme Inhibitors
Open accessAbstract
Extracts, subfractions, isolated anthocyanins and isolated procyanidins B2, B5 and C1 from the berries and bark of Aronia melanocarpa were investigated for their antioxidant and enzyme inhibitory activities. Four different bioassays were used, namely scavenging of the diphenylpicrylhydrazyl (DPPH) radical, inhibition of 15-lipoxygenase (15-LO), inhibition of xanthine oxidase (XO) and inhibition of α-glucosidase. Among the anthocyanins, cyanidin 3-arabinoside possessed the strongest and cyanidin 3-xyloside the weakest radical scavenging and enzyme inhibitory activity. These effects seem to be influenced by the sugar units linked to the anthocyanidin. Subfractions enriched in procyanidins were found to be potent α-glucosidase inhibitors; they possessed high radical scavenging properties, strong inhibitory activity towards 15-LO and moderate inhibitory activity towards XO. Trimeric procyanidin C1 showed higher activity in the biological assays compared to the dimeric procyanidins B2 and B5. This study suggests that different polyphenolic compounds of A. melanocarpa can have beneficial effects in reducing blood glucose levels due to inhibition of α-glucosidase and may have a potential to alleviate oxidative stress.
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Cites
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
Manach, C., Williamson, G., Morand, C., Scalbert, A., & Rémésy, C. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.230s · Cited by 4,219
Oxidative Stress and Vascular Disease
Madamanchi, N. R., Vendrov, A., & Runge, M. S. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000150649.39934.13 · Cited by 1,618 · cited 1×
“Reactive oxygen species can be generated by the prooxidative enzyme, XO, and the peroxidative enzyme, 15-LO, in vascular cells [31].”
BackgroundPacher, P., Nivorozhkin, A., & Szabó, C. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.1.6 · Cited by 1,218
Cited by
The Immunomodulatory and Anti-Inflammatory Role of Polyphenols
Yahfoufi, N., Alsadi, N., Jambi, M., & Matar, C. (2018) · Nutrients · doi:10.3390/nu10111618 · Cited by 1,737
Podsędek, A., Majewska, I., Redzynia, M., Sosnowska, D., & Koziołkiewicz, M. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf5008264 · Cited by 266
Composition and physicochemical properties of dried berry pomace
Reißner, A., Al‐Hamimi, S., Quiles, A., Schmidt, C., Struck, S., Hernando, I., Turner, C., & Rohm, H. (2019) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.9302 · Cited by 121
Metadata
- Authors
- Bräunlich, M., Slimestad, R., Wangensteen, H., Brede, C., Malterud, K., & Barsett, H.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2013-03-04
- Volume
- 5
- Issue
- 3
- Pages
- 663-678
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2082856983
- Cited by
- 187
- References
- 3
- FWCI
- 7.76
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bräunlich, M., Slimestad, R., Wangensteen, H., Brede, C., Malterud, K., & Barsett, H. (2013). Extracts, Anthocyanins and Procyanidins from Aronia melanocarpa as Radical Scavengers and Enzyme Inhibitors. Nutrients. https://doi.org/10.3390/nu5030663
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