The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Flavonoid Bioavailability and Attempts for Bioavailability Enhancement
Open accessAbstract
Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid classes, flavonols are distributed ubiquitously among different plant foods whereas appreciable amounts of isoflavones are found in leguminous plant-based foods. Flavonoids have shown promising health promoting effects in human cell culture, experimental animal and human clinical studies. They have shown antioxidant, hypocholesterolemic, anti-inflammatory effects as well as ability to modulate cell signaling and gene expression related disease development. Low bioavailability of flavonoids has been a concern as it can limit or even hinder their health effects. Therefore, attempts to improve their bioavailability in order to improve the efficacy of flavonoids are being studied. Further investigations on bioavailability are warranted as it is a determining factor for flavonoid biological activity.
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Cites
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“Phase 2 metabolism is known to affect the bioavailability of flavonoids in humans [12].”
BackgroundThe Effect of Fruit and Vegetable Intake on Risk for Coronary Heart Disease
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“Flavonols Sugars and their position affects bioavailability [44].”
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Important Flavonoids and Their Role as a Therapeutic Agent
Ullah, A., Munir, S., Badshah, S. L., Khan, N., Ghani, L., Poulson, B. G., Emwas, A.-H., & Jaremko, M. (2020) · Molecules · doi:10.3390/molecules25225243 · Cited by 1,696
Flavonoids as Potential Anti-Inflammatory Molecules: A Review
Al-Khayri, J. M., Sahana, G. R., Nagella, P., Joseph, B. V., Alessa, F. M., & Al-Mssallem, M. Q. (2022) · Molecules · doi:10.3390/molecules27092901 · Cited by 1,100
Chandrakala, V., Aruna, V., & Angajala, G. (2022) · Emergent Materials · doi:10.1007/s42247-021-00335-x · Cited by 768
The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging
Yu, C., & Xiao, J.-H. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/6635460 · Cited by 537
Repairing mitochondrial dysfunction in disease
Sorrentino, V., Menzies, K. J., & Auwerx, J. (2018) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010716-104908 · Cited by 337
Metadata
- Authors
- Thilakarathna, S., & Rupasinghe, H.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2013-08-28
- Volume
- 5
- Issue
- 9
- Pages
- 3367-3387
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W1981930609
- Cited by
- 787
- References
- 5
- FWCI
- 17.20
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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