The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Biomarkers of Aging: From Function to Molecular Biology
Open accessAbstract
Aging is a major risk factor for most chronic diseases and functional impairments. Within a homogeneous age sample there is a considerable variation in the extent of disease and functional impairment risk, revealing a need for valid biomarkers to aid in characterizing the complex aging processes. The identification of biomarkers is further complicated by the diversity of biological living situations, lifestyle activities and medical treatments. Thus, there has been no identification of a single biomarker or gold standard tool that can monitor successful or healthy aging. Within this short review the current knowledge of putative biomarkers is presented, focusing on their application to the major physiological mechanisms affected by the aging process including physical capability, nutritional status, body composition, endocrine and immune function. This review emphasizes molecular and DNA-based biomarkers, as well as recent advances in other biomarkers such as microRNAs, bilirubin or advanced glycation end products.
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Citations
Cites
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Cited by
Biomarkers of aging for the identification and evaluation of longevity interventions
Moqri, M., Herzog, C., Poganik, J. R., Justice, J., Belsky, D. W., Higgins-Chen, A., Moskalev, A., Fuellen, G., Cohen, A. A., Bautmans, I., et al. (2023) · Cell · doi:10.1016/j.cell.2023.08.003 · Cited by 736
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Justice, J. N., Ferrucci, L., Newman, A. B., Aroda, V. R., Bahnson, J. L., Divers, J., Espeland, M. A., Marcovina, S., Pollak, M. N., Kritchevsky, S. B., et al. (2018) · GeroScience · doi:10.1007/s11357-018-0042-y · Cited by 359
Circulating Exosomal miRNA as Diagnostic Biomarkers of Neurodegenerative Diseases
Wang, L., & Zhang, L. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00053 · Cited by 164
Obas, V., & Vasan, R. S. (2018) · Clinical Science · doi:10.1042/cs20171156 · Cited by 148
Metadata
- Authors
- Wagner, K.-H., Cameron-Smith, D., Wessner, B., & Franzke, B.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2016-06-02
- Volume
- 8
- Issue
- 6
- Pages
- 338
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2410374774
- Cited by
- 304
- References
- 19
- FWCI
- 8.18
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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